anti-Souris LHB anticorps pour Enzyme Immunoassay

Recommended LHB Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Luteinizing Hormone beta Polypeptide (LHB) Anticorps
  • cgb4
  • hlhb
  • xlhb
  • lhb-A
  • lsh-b
  • LH
  • LH-B
  • LSH-B
  • LSH-beta
  • CGB4
  • hLHB
  • luteinizing hormone beta polypeptide
  • luteinizing hormone beta
  • lhb
  • Lhb
  • LHB
Épitope
AA 21-40, N-Term
4
4
3
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
133
12
9
7
1
1
1
1
1
1
1
1
1
1
Hôte
Lapin
107
40
3
1
Clonalité
Polyclonal
Conjugué
Cet anticorp LHB est non-conjugé
10
8
7
5
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
Application
Dot Blot (DB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
58
49
40
28
15
14
11
8
7
3
2
2
2
1
1
1
1
1
1
1
1
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N° du produit ABIN493089
462,00 €
Plus frais de livraison 40,00 € et TVA
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
1 ABIN493091 DB EIA IHC (fro) Rabbit AA 115-134, C-Term Connectez-vous pour afficher Polyclonal 1

anti-LHB anticorps pour Enzyme Immunoassay mieux référencés

anti-LHB Anticorps

Application / Reactivité Rat (Rattus) Souris Humain
Dot Blot (DB) 2 Anticorps 2 Anticorps 2 Anticorps
ELISA 6 Anticorps 3 Anticorps
Enzyme Immunoassay (EIA) 2 Anticorps 2 Anticorps
Immunocytochemistry (ICC) 2 Anticorps
Immunofluorescence (fixed cells) (IF/ICC) 1 Anticorps
Immunohistochemistry (IHC) 3 Anticorps 2 Anticorps
Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Anticorps 2 Anticorps
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 1 Anticorps
Immunoprecipitation (IP) 1 Anticorps
Western Blotting (WB) 7 Anticorps 5 Anticorps
Cytometry by Time of Flight (CyTOF) 2 Anticorps
Detection (D) 1 Anticorps

General

Antigène Luteinizing Hormone beta Polypeptide (LHB) Anticorps
Épitope AA 21-40, N-Term
(4), (4), (3), (1), (1), (1), (1)
Reactivité Humain, Souris, Rat (Rattus)
(133), (12), (9), (7), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Hôte Lapin
(107), (40), (3), (1)
Clonalité
Polyclonal
Conjugué Cet anticorp LHB est non-conjugé
(10), (8), (7), (5), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Dot Blot (DB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
(58), (49), (40), (28), (15), (14), (11), (8), (7), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 1 référence disponible
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Détail du produit anti-LHB anticorps

Détail du antigène LHB Information d'application Stockage ProductDetails: References for anti-LHB antibody (ABIN493089) Images
Séquence RPW CHP INA ILA VEK EGC PV
Specificité This antibody labels gonadotrophs in pituitary sections. It does not react to other cellular proteins that are tested during characterization of this antibody.
Réactivité croisée (Details) Species reactivity (tested):Human, Mouse, Rat.
Purification Affinity Chromatography.
Immunogène Synthetic peptide corresponding to 21-40 amino acids of Human LH

Détail du antigène LHB

Détail du produit anti-LHB anticorps Information d'application Stockage ProductDetails: References for anti-LHB antibody (ABIN493089) Images Haut de la page
Antigène
Autre désignation Luteinizing Hormone beta (LSH-Beta) (LHB Antibody Extrait)
Sujet The pituitary hormones, luteinizing hormone (lutropin, LH) and follicle stimulating hormone (follitropin, FSH) as well as related placental hormones, chorionic gonadotropin and CG, are referred to as gonadotropic hormones because of their action on gonad cells. These three hormones are structurally related to each other as well as to thyroid stimulating hormone (TSH). Because of their similar structure and composition and glycoprotein nature, LH, TSH, GC and FSH, these hormones are referred to as glycoprotein hormones. All these hormones are heterodimeric in nature composed of two un-identical subunits, alpha and beta which are non-covalently associated, Among humans and other species, the Alpha subunit is identical for all these hormones and is coded by a single gene, where is beta subunits are distinct but homologous and arise from separate genes. The individual hormone subunits and peptides derived from them have shown some binding activities to their respective receptors, the association of alpha and beta subunits clearly is required for optimal activation and physiological responses elicited by these hormones. Within the heterodimeric hormones, the beta subunit confors the binding activity to its respective receptor. The LH and CG beta subunits have 85 % sequence identity in their first 114 amino acids, the LH/CG receptors can recognize either of the pituitary LH or placental CG hormones. The alpha and beta subunits of LH, CG and FSH are highly glycosylated (1). The alpha subunit has two N-linked oligosdaccharide chain at position 52 and 78 and beta subunits have one in LH and TSH and two in CG and FSH. The CG beta subunit also has an extension of serine O-linked carbohydrates at carboxyl end which help is plasma half like of CG compared to other glycohormone beta subunits. The N-linked oligosaccharides on FSH are sialylated whereas LH and TSH are sialylated and sulfated. There are 10-12 cysteins forming 3 disulfide bonds referred to as Synonyms: LH-B, LHB, LSH-beta, Luteinizing hormone subunit beta, Lutropin beta chain, Lutropin subunit beta
ID gène 3972
NCBI Accession NP_000885
UniProt P01229
Pathways Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, C21-Steroid Hormone Metabolic Process

Information d'application

Détail du produit anti-LHB anticorps Détail du antigène LHB Stockage ProductDetails: References for anti-LHB antibody (ABIN493089) Images Haut de la page
Indications d'application Dot blot. ELISA: 1/50,000 in dilution buffer. Immunohistochemistry on Frozen Sections: 1/250.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Stockage

Détail du produit anti-LHB anticorps Détail du antigène LHB Information d'application ProductDetails: References for anti-LHB antibody (ABIN493089) Images Haut de la page
Concentration 0.59-0.72 mg/mL
Buffer Stabilization buffer with 0.02 % Sodium Azide as preservative.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

ProductDetails: References for anti-LHB antibody (ABIN493089)

Détail du produit anti-LHB anticorps Détail du antigène LHB Information d'application Stockage Images Haut de la page
Background publications

Sairam: "Role of carbohydrates in glycoprotein hormone signal transduction." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 3, Issue 8, pp. 1915-26, 1989