anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) Anticorps

The protein encoded by ABCC4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. De plus, nous expédions ABCC4 Kits (12) et ABCC4 Protéines (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ABCC4 10257 O15439
ABCC4 239273  
ABCC4 170924  
Comment commander chez anticorps-enligne
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Commandez enligne
  • orders@anticorps-enligne.fr

Top anti-ABCC4 Anticorps sur anticorps-enligne.fr

Showing 10 out of 133 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Chèvre Inconjugué ELISA, IHC ABIN185302 staining (0.5µg/ml) of rat renal cortex membranes (20µg total protein per lane). Detected by western blot using chemiluminescence. Data kindly provided by Dr. Antje Steinbach, Ernst-Moritz-Arndt University of Greifswald. ABIN185302 (2.5µg/ml) staining of paraffin embedded Human Prostate. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 100 μg Connectez-vous pour afficher 6 to 7 Days
$429.62
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-ABCC4 Antibody Titration: 1.0 ug/ml Positive Control: 721_B Whole Cell ABCC4 is supported by BioGPS gene expression data to be expressed in 721_B 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Souris Inconjugué ELISA, IHC, WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.73 KDa) . Dilution: 1:500~1000 100 μg Connectez-vous pour afficher 8 to 11 Days
$461.00
Détails
Humain Chèvre Inconjugué ICC, IF, IHC (p), IHC, ELISA, WB Immunohistochemistry: MRP4 Antibody [ABIN250309] - NB100-1478 (2.5ug/ml) staining of paraffin embedded Human Prostate. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. ABIN250309 staining (0.5µg/ml) of Rat renal cortex membranes (20µg total protein per lane). Detected by western blot using chemiluminescence. Data kindly provided by Dr. Antje Steinbach, Ernst-Moritz-Arndt University of Greifswald 0.1 mg Connectez-vous pour afficher 7 to 9 Days
$485.88
Détails
Humain Souris Inconjugué FACS, IHC, ELISA, WB 100 μg Connectez-vous pour afficher 11 to 16 Days
$426.40
Détails
Humain Lapin Inconjugué IHC (p), WB Anti-MRP4 Picoband antibody,  IHC(P): Rat Intestine Tissue Anti-MRP4 Picoband antibody,  IHC(P): Mouse Intestine Tissue 100 μg Connectez-vous pour afficher 4 to 6 Days
$280.00
Détails
Humain Lapin Inconjugué WB Western blot analysis of MRP4 expression in COLO320 whole cell lysates. MRP4 at 190KD was detected using rabbit anti- MRP4 Antigen Affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002). 100 μg Connectez-vous pour afficher 4 to 6 Days
$240.00
Détails
Humain Lapin Inconjugué WB Western blot analysis of anti-ABCC4 Antibody (C-term) (ABIN391639) in CEM cell line lysates (35 µg/lane). ABCC4 (arrow) was detected using the purified polyclonal antibody. 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Chèvre Inconjugué ELISA, WB   100 μg Connectez-vous pour afficher 6 to 7 Days
$429.62
Détails
Humain Lapin Inconjugué EIA, WB Western blot analysis of anti-ABCC4 Antibody (C-term) in CEM cell line lysates (35ug/lane). ABCC4 (arrow) was detected using the purified Pab. 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails

anti-ABCC4 Anticorps mieux référencés

  1. Human Polyclonal ABCC4 Primary Antibody pour ICC, IF - ABIN250309 : Cheng, Ren, Jackson: Multidrug resistance protein 4 mediates cAMP efflux from rat preglomerular vascular smooth muscle cells. dans Clinical and experimental pharmacology & physiology 2010 (PubMed)
    Show all 8 Pubmed References

  2. Human Polyclonal ABCC4 Primary Antibody pour ELISA, IHC - ABIN185302 : Schuetz, Connelly, Sun, Paibir, Flynn, Srinivas, Kumar, Fridland: MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs. dans Nature medicine 1999 (PubMed)
    Show all 6 Pubmed References

  3. Human Monoclonal ABCC4 Primary Antibody pour FACS, IHC - ABIN1724860 : Bebes, Kis, Nagy, Kurunczi, Polyánka, Bata-Csörgo, Kemény, Dobozy, Széll: The expressions of ABCC4 and ABCG2 xenobiotic transporters in human keratinocytes are proliferation-related. dans Archives of dermatological research 2012 (PubMed)

Plus d’anticorps contre ABCC4 partenaires d’interaction

Human ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) interaction partners

  1. MRP4 is mainly responsible for the efflux of lamivudine and entecavir in hepatocyte cultures.

  2. Data suggest that targeting the ATP binding cassette subfamily C (Montrer CYP Anticorps) member 4 (ABCC4)-membrane palmitoylated protein 1 (MPP1 (Montrer MPP1 Anticorps)) protein complex can lead to new therapies to improve treatment outcome of acute myeloid leukemia (Montrer BCL11A Anticorps) (AML (Montrer RUNX1 Anticorps)).

  3. A functional polymorphism in the ABCC4 promoter, -1508A>G, may increase extracellular 15-hydroxyeicosatetraenoic acid, sphingosine-1-phosphate, and periostin (Montrer POSTN Anticorps) levels, contributing to airway inflammation in asthmatics.

  4. MRP4 localisation and function are regulated by interactions with SNX27 (Montrer SNX27 Anticorps), PSD95 (Montrer DLG4 Anticorps), and AP3B1 (Montrer AP3B1 Anticorps).

  5. MRP4 exports prostaglandin E2 PGE2 and contributes to cell migration/metastasis in basal/triple negative breast cancer cells.

  6. This study provides direct evidence that ganciclovir (GCV) is a substrate of the efflux transporter MRP4 and suggests that the intracellular fate of GCV is significantly influenced by ABCC4 rs11568658 variant in renal transplant recipients receiving GCV

  7. Multidrug resistance protein 4 (MRP4) is a critical protein associated with the antiviral efficacy of nucleos(t)ide analogue (NA)s, and combination therapy of NA and MRP inhibitors could reduce the dosage for long-term NA use. MRP4 expression is an important factor predicting treatment failure in chronic hepatitis B patients and will provide a potential therapeutic target against hepatitis B virus.

  8. All patients with both NUDT15 (Montrer NUDT15 Anticorps) rs116855232 heterozygous variants and ABCC4 rs3765534 variants suffered from severe leukopenia and required 6-mercaptopurine dose reduction to less than 35 mg/m(2)/da

  9. ABCC4 variant (rs4148500) was significantly associated with hyperuricemia and gout. The gout risk allele was associated with fractional excretion of uric acid in male individuals.

  10. ABCC4 functional SNP in the 3' splice acceptor site of exon 8 (G912T) is associated with unfavorable clinical outcome in children with acute lymphoblastic leukemia

Mouse (Murine) ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) interaction partners

  1. The diversity at N-termini in these protein isoforms explains the diverse function of ABCC4 in mouse.

  2. ABCC4 plays a protective role against cytarabine-mediated insults in leukemic and host myeloid cells.

  3. P-gp, Bcrp, Mrp1 and Mrp4 are differentially expressed at the outer and inner blood retinal barrier, resulting in an altered ability to limit substrate distribution at the retina as compared with the blood brain barrier

  4. These findings have important clinical implications because they directly highlight an important relationship between ABCC4 transporter function and phosphodiesterases in accounting for the cAMP-directed activity of antithrombotic agents.

  5. A novel cAMP-dependent mechanism for MRP4-mediated regulation of fibroblast migration and indicated that PKA and actin play important roles as downstream effectors.

  6. Loss of MRP4 is associated with impaired platelet activation and cAMP homeostasis

  7. Upregulation of COX-2 in lung cancer promotes overexpression of MRP4 via PGE2-dependent pathway

  8. role of MRP4 in thrombus formation

  9. NHERF3 is a key regulator of organic transport in the kidney, particularly MRP4-mediated clearance of drug molecules.

  10. Abcc4 in the stomach facilitates the oral absorption of dasatinib, and it possibly plays a similar role for other orally administered substrates, such as acetylsalicylic acid.

ABCC4 profil antigène

Profil protéine

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined\; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms.

Gene names and symbols associated with ABCC4

  • ATP binding cassette subfamily C member 4 (ABCC4) anticorps
  • multidrug resistance-associated protein 4 (LOC515333) anticorps
  • multidrug resistance-associated protein 4 (LOC616707) anticorps
  • multidrug resistance-associated protein 4 (LOC695407) anticorps
  • ATP binding cassette subfamily C member 4 (abcc4) anticorps
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (Abcc4) anticorps
  • ATP binding cassette subfamily C member 4 (Abcc4) anticorps
  • D630049P08Rik anticorps
  • EST170205 anticorps
  • MOAT-B anticorps
  • MOATB anticorps
  • Mrp4 anticorps

Protein level used designations for ABCC4

multidrug resistance-associated protein 4 , ATP-binding cassette, sub-family C (CFTR/MRP), member 4 , ATP-binding cassette protein C4-like , multidrug resistance-associated protein 4-like , ATP-binding cassette sub-family C member 4 , MRP/cMOAT-related ABC transporter , bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4) , canalicular multispecific organic anion transporter (ABC superfamily) , multi-specific organic anion transporter B , multispecific organic anion transporter B , ABC-tranporter , ATP-binding cassette protein C4

GENE ID SPECIES
485523 Canis lupus familiaris
515333 Bos taurus
616707 Bos taurus
695407 Macaca mulatta
100027089 Monodelphis domestica
100050431 Equus caballus
100081616 Ornithorhynchus anatinus
100391624 Callithrix jacchus
100466405 Ailuropoda melanoleuca
100491006 Xenopus (Silurana) tropicalis
10257 Homo sapiens
239273 Mus musculus
170924 Rattus norvegicus
Fournisseurs de qualité sélectionnés pour anti-ABCC4 (ABCC4) Anticorps
Avez-vous cherché autre chose?