anti-Adherens Junctions Associated Protein 1 (AJAP1) Anticorps

Plays a role in cell adhesion and cell migration (By similarity).. De plus, nous expédions AJAP1 Protéines (8) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
AJAP1 230959 A2ALI5
AJAP1 687031 Q4W8E7
AJAP1 55966 Q9UKB5
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Top anti-AJAP1 Anticorps sur

Showing 10 out of 24 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Lapin Inconjugué ELISA, IHC, IHC (p), WB Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE) 0.05 mg 11 to 14 Days
Humain Lapin Inconjugué ELISA, ICC, WB   0.1 mg 2 to 3 Days
Humain Lapin Inconjugué IHC (p), ELISA, WB   50 μg 12 to 14 Days
Souris Mouton Inconjugué ELISA, WB   100 μg 11 to 16 Days
Humain Lapin Alexa Fluor 350 IF (p)   100 μL 3 to 7 Days
Humain Lapin Alexa Fluor 488 IF (p)   100 μL 3 to 7 Days
Humain Lapin Alexa Fluor 555 IF (p)   100 μL 3 to 7 Days
Humain Lapin Alexa Fluor 647 IF (p)   100 μL 3 to 7 Days
Humain Lapin Cy7 IF (p)   100 μL 3 to 7 Days
Humain Lapin Cy3 IF (p)   100 μL 3 to 7 Days

Plus d’anticorps contre AJAP1 partenaires d’interaction

Human Adherens Junctions Associated Protein 1 (AJAP1) interaction partners

  1. This study demonstrated that AJAP1 acted as a putative tumor suppressor while beta-catenin nuclear localization positively fed back on EGF/EGFR-attenuated AJAP1 expression in breast cancer, which might be beneficial to develop new therapeutic targets for decreasing nuclear beta-catenin-mediated malignancy in breast cancer.

  2. Stable overexpression of AJAP1 promotes adherence, decreases invasion of glioma cells through an extracellular-like matrix, and slows migration in the presence of laminin. These observations are reversed by gene knockdown using multiple siRNAs. Additionally, overexpression of AJAP1 decreases colony formation in glioma cells.

  3. AJAP1 blocked epithelial-to-mesenchymal transition by interacting with beta-catenin and inhibiting its nuclear translocation, which suppressed zinc finger E-box binding homeobox 1 (ZEB1) transcription.

  4. EGFR/EGFRvIII remodels the cytoskeleton via epigenetic silencing of AJAP1 in glioma cells.

  5. Reduced Expression of Adherens Junctions Associated Protein 1 is associated with Recurrence of Hepatocellular Carcinoma After Curative Hepatectomy.

  6. These findings indicate that downregulated AJAP1 transcription may serve as a novel tumor biomarker to predict recurrence of ESCC after esophagectomy.

  7. Article summarizes and discusses current knowledge that may identify AJAP1 as a tumor suppressor in gliomas. [Review]

  8. Results show that AJAP1 is dysregulated at an early stage of gliomagenesis and may suppress glioma cell invasion and proliferation, which suggests that AJAP1 may be a potential diagnostic and prognostic marker for gliomas

  9. AJAP1 suppressed the expression of MAGEA2 and inhibited the transcriptional activity of MAGEA2 in glioma cells.

  10. We also identified a significant genetic association between caries of the mid- dentition tooth surfaces and AJAP1 (p value = 2e-8), a gene possibly involved in tooth development.

  11. This work shows the significant loss of expression of AJAP1 in glioblastoma and provides evidence of its role in the highly migratory characteristic of these tumors.

  12. Both genetic (gene deletion) and epigenetic alterations (promoter methylation) are likely mechanisms that inactivate the putative tumor suppressor AJAP1 in gliomas, which contributes to poor prognosis.

  13. Data show that overexpression of shrew-1 leads to preformation of an E-cadherin/EGF receptor/HER2/src-kinase/shrew-1 signaling complex and accelerated E-cadherin internalization.

  14. While a mutation was not detected in the coding region of the SHREW1 gene in oligodendrogliomas, SHREW1 expression restoration resulted in suppression of cell adhesion and migration, thus, SHREW1 inactivation may lead to oligodendroglial tumorigenesis.

  15. Adaptor protein complex AP-1B is involved in retaining shrew-1 at the basolateral membrane by postendocytic sorting mechanisms.

  16. shrew-1 has a function in the regulation of cellular invasion, which may involve its interaction with CD147

  17. synergism between a signal peptide and a transmembrane segment to mediate plasma membrane localization is essential for structural and/or functional integrity of shrew-1

AJAP1 profil antigène

Profil protéine

Plays a role in cell adhesion and cell migration (By similarity).

Gene names and symbols associated with AJAP1

  • adherens junction associated protein 1 (Ajap1) anticorps
  • adherens junctions associated protein 1 (Ajap1) anticorps
  • adherens junctions associated protein 1 (AJAP1) anticorps
  • Gm573 anticorps
  • MOT8 anticorps
  • neumo48 anticorps
  • RP3-426F10.1 anticorps
  • SHREW-1 anticorps
  • SHREW1 anticorps

Protein level used designations for AJAP1

adherens junction-associated protein 1 , likely ortholog of H. sapiens transmembrane protein SHREW1 , Neumo48 , adherens junction associated protein 1 , membrane protein shrew-1 , transmembrane protein SHREW1

230959 Mus musculus
687031 Rattus norvegicus
55966 Homo sapiens
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