Adrenergic Receptor, alpha 1d Protéines (ADRA1D)

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. De plus, nous expédions Adrenergic Receptor, alpha 1d Anticorps (38) et Adrenergic Receptor, alpha 1d Kits (7) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
ADRA1D 11550  
Rat ADRA1D ADRA1D 29413 P23944
ADRA1D 146 P25100
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Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Souris rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Connectez-vous pour afficher 50 to 55 Days
$5,355.45
Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,869.04
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ADRA1D Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Mouse (Murine)
,
Human
,

Plus protéines pour Adrenergic Receptor, alpha 1d (ADRA1D) partenaires d'interaction

Mouse (Murine) Adrenergic Receptor, alpha 1d (ADRA1D) interaction partners

  1. Our results suggest that stimulation of alpha1-ARs (Montrer SLURP1 Protéines) results in a favorable metabolic profile of increased glucose tolerance, cardiac glucose uptake, leptin (Montrer LEP Protéines) secretion and increased whole body lipid metabolism that may contribute to its previously recognized cardioprotective and neuroprotective benefits.

  2. Erythropoietin (Montrer EPO Protéines) seems to reverse sepsis-induced vasoplegia to NE through the preservation of alpha1D adrenoceptor mRNA/protein expression, inhibition of GRK2 (Montrer ADRBK1 Protéines)-mediated desensitization, and attenuation of NO overproduction in the mouse aorta.

  3. in mouse ureters: the mRNA for the alpha1A-adrenoceptor was more prevalent than those for the alpha1B- and alpha1D-adrenoceptors

  4. The right ventricle inotropic response to alpha(1)-adrenergic receptors is switched from negative to positive in heart failure, through a pathway involving increased myofilament Ca(2 (Montrer CA2 Protéines)+) sensitivity.

  5. mouse hearts lacking alpha(1A)- and alpha(1B (Montrer CACNA1B Protéines))-adrenergic receptors retain functional alpha(1)-adrenergic receptor responses involving decreases of coronary flow and ventricular pressure that reflect alpha(1D)-adrenergic receptor-mediated vasoconstriction

  6. alpha1D-adrenergic receptors are regulated by syntrophins through a PDZ domain-mediated interaction

  7. Couplings of 5-HT2B (Montrer HTR2B Protéines) and adrenergic alpha1D autoreceptors to reactive oxygen species and TNF-alpha (Montrer TNF Protéines) signaling control neurotransmitter metabolism in 1C11-derived neuronal cells.

  8. These results demonstrate that alpha(1)-adrenoceptors, particularly alpha(1A)-adrenoceptors, are required for normal contractility of the vas (Montrer AVP Protéines) deferens and consequent sperm ejaculation as well as having a function in fertility

  9. Norepinephrine acts through both alpha1- and beta-adrenergic receptors located on the soma/dendrites of GnRH neurons to directly suppress their excitability throughout the estrous cycle and after ovariectomy.

Human Adrenergic Receptor, alpha 1d (ADRA1D) interaction partners

  1. Hetero-oligomerization of a1B (Montrer A1BG Protéines)/D-adrenergic receptor with the chemokine (C-X-C motif) receptor 4 (Montrer CXCR4 Protéines):atypical chemokine receptor 3 heteromeric complex is required for a1B (Montrer A1BG Protéines)/Dadrenergic receptor function.

  2. expression of carboxyl terminus-truncated alpha1D-adrenoceptors alters ERK (Montrer EPHB2 Protéines) and p38 (Montrer CRK Protéines) phosphorylation state.

  3. alpha1A-adrenergic receptors are stably expressed and stimulate cell migration and TGF-beta1 (Montrer TGFB1 Protéines), IGF-1 (Montrer IGF1 Protéines), hyaluronan and PIP (Montrer PIP Protéines) production in human skin fibroblasts.

  4. Data show that alpha-dystrobrevin (Montrer DTNA Protéines)-1 recruits alpha-catulin (Montrer CTNNAL1 Protéines), which supersensitizes alpha(1D)-AR functional responses by recruiting effector molecules to the signalosome.

  5. Genetic characteristics associated with response to domperidone therapy included polymorphisms in the drug transporter gene ABCB1 (Montrer ABCB1 Protéines), the potassium channel (Montrer KCNAB2 Protéines) KCNH2 (Montrer KCNH2 Protéines) gene, and alpha1D--adrenoceptor ADRA1D gene.

  6. Data show thah activation of alpha(1)A- or alpha(1)B-adrenergic receptors inhibits serum-promoted cell proliferation, whereas alpha(1)D-AR activation does not show such an inhibitory effect.

  7. These studies suggest that gC1qR (Montrer C1QBP Protéines) interacts specifically with alpha1B- and alpha1D-, but not alpha1A-ARs (Montrer SLURP1 Protéines), and this interaction depends on the presence of an intact C-tail.

  8. Human ureter was endowed with each alpha1 AR subtype, although alpha1D and alpha1A ARs (Montrer SLURP1 Protéines) were prevalent over alpha1B ARs (Montrer SLURP1 Protéines).

  9. alpha1D-adrenergic receptors are regulated by syntrophins through a PDZ domain-mediated interaction

  10. Differential methylation of proximal GC boxes in the ADRA1D promoter disrupts Sp1 (Montrer PSG1 Protéines) binding in a cell-specific manner resulting in repression of basal alpha1dAR expression.

Profil protéine Adrenergic Receptor, alpha 1d (ADRA1D)

Profil protéine

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1D-adrenergic receptor. Similar to alpha-1B-adrenergic receptor gene, this gene comprises 2 exons and a single intron that interrupts the coding region.

Gene names and symbols associated with ADRA1D

  • adrenergic receptor, alpha 1d (Adra1d)
  • adrenoceptor alpha 1D (Adra1d)
  • adrenoceptor alpha 1D (ADRA1D)
  • Adra-1 Protéine
  • ADRA1 Protéine
  • ADRA1A Protéine
  • ADRA1R Protéine
  • Adrd1 Protéine
  • ALPHA1 Protéine
  • alpha1D-AR Protéine
  • DAR Protéine
  • dJ779E11.2 Protéine
  • Gpcr8 Protéine
  • Spr8 Protéine
  • [a]1d Protéine

Protein level used designations for ADRA1D

alpha-1A adrenergic receptor , alpha-1D adrenergic receptor , alpha-1D adrenoceptor , alpha-1D adrenoreceptor , RA42 , adrenergic receptor delta1 , adrenergic receptor, alpha 1d , adrenergic, alpha-1D-, receptor , alpha 1D-adrenoceptor , alpha 1D-adrenoreceptor , adrenergic, alpha -1D-, receptor , adrenergic, alpha-1A-, receptor , alpha-1D-adrenergic receptor , alpha-adrenergic receptor 1a , alpha 1d adrenoceptor

GENE ID SPECIES
11550 Mus musculus
29413 Rattus norvegicus
146 Homo sapiens
552898 Sus scrofa
100009398 Oryctolagus cuniculus
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