Amylase, alpha 1A (Salivary) (AMY1A) Kits ELISA

Human Amylase, alpha 1A (Salivary) (AMY1A) interaction partners

1. High amylase expression is associated with diabetes.

2. A significant link between serum amylase activity and ABO blood type in Chinese subjects.

3. High-AMY1-gene copy number subjects had higher levels of salivary Porphyromonas; their gut microbiota had increased abundance of resistant starch-degrading microbes, produced higher levels of short-chain fatty acids, and drove higher adiposity when transferred to germ-free mice. This study establishes AMY1-gene copy number as a genetic factor associated with microbiome composition and function.

4. Diurnal patterns of salivary alpha amylase and salivary IgA exist in healthy young children and are not affected by their nutrient intake, sex, Asian ethnicity, and body mass index.

5. 66 proteins that interact with amylase in whole saliva were identified.

6. AMY1 copy number was significantly correlated with the variation observed in salivary amylase production and enzyme activity but did not explain the majority of observed variation between individuals. AMY1-odd and AMY1-even haplotypes showed a different relationship between copy number and expression levels, but the difference was not statistically significant.

7. Alcohol dependent patients showed significantly lower stress-related salivary alpha-amylase activity than healthy controls.

8. Results from 2 case-control cohorts of Chinese and Malays, show no previously reported association between AMY1 and obesity or body mass index.

9. It was concluded that the genetic variant determining starch metabolism influences the response to weight-loss dietary intervention. Overweight and obese individuals carrying the AMY1-AMY2 rs11185098 genotype associated with higher amylase activity may have greater loss of adiposity during low-calorie diet interventions.

10. higher levels of sAA in EHS participants

11. Serum amylase levels in the normal range are positively associated with integrated islet beta cell function in patients with early type 2 diabetes.

12. Our findings suggest an effect of the interaction between starch intake and AMY1 copy number on obesity. Individuals with high starch intake but low genetic capacity to digest starch had the lowest BMI, potentially because larger amounts of undigested starch are transported through the gastrointestinal tract, contributing to fewer calories extracted from ingested starch.

13. Data show that carcinoembryonic antigen (CEA) modestly differentiated between mucinous and nonmucinous lesions, and amylase did not distinguish intraductal papillary mucinous neoplasms (IPMNs) from mucinous cystadenomas (MCAs).

14. genetic association studies in a population of men in Republic of Korea: Data suggest that low AMY1A gene copy number is associated with high insulin resistance and thus with genetic predisposition to diabetes type 2 and metabolic syndrome.

15. The purpose of this study was to a) determine the heart rate variability (HRV) and saliva markers of immunity (salivary immunoglobulin A; sIgA) and stress (salivary alpha-amylase; sAA) responses to chronic training in elite swimmers with a disability.

16. Alpha-amylase in blood increases after pharmacological activation of the adrenergic pathways suggesting that sympathetic receptors are responsible for these changes. Psychological stress, however, does not seem to have an impact on alpha-amylase in blood

17. low serum amylase level is significantly associated with increased risk of gestational diabetes mellitus

18. Diurnal and stress-response salivary alpha amylase patterns were related to child adiposity: decreased morning alpha amylase was associated with increased BMI.

19. Our current study suggests putative benefits of high number of AMY1 copies (and related production of salivary amylase) on energy metabolism in Mexican children.

20. Splenic asthenia children had positive correlations between AMY1 copy number and sAA activity before or after citric acid stimulation.