C-Type Lectin Domain Family 4, Member E (CLEC4E) Kits ELISA

Human C-Type Lectin Domain Family 4, Member E (CLEC4E) interaction partners

1. Mincle has the ability to survey mycolate-derived glycolipids from actinomycetes, distinguishing non-pathogenic (e.g. Rhodococcus spp.) and pathogenic (e.g. Mycobacterium tuberculosis) species on the basis of alpha-chain (Montrer FCGRT Kits ELISA) length.

2. combination adjuvant systems demonstrate markedly different immune activation with age, with combined DC activation via Macrophage-inducible C-type lectin and TLR7 (Montrer TLR7 Kits ELISA)/8 representing a novel approach to enhance the efficacy of early-life vaccines.

3. We here show that Mincle gene expression was induced in alveolar macrophages and neutrophils in bronchoalveolar lavage fluids of mice and patients with pneumococcal pneumonia

4. a nonredundant role for Clec4e in coordinating major biological pathways involved in atherosclerosis

5. CLEC4E expression is significantly upregulated in human masticatory mucosa during wound healing

6. The expression of Mincle increases significantly during the early period of Aspergillus fumigatus infection, while expression of eight corresponding cytokines changes. Mincle, as a pattern recognition receptor, may play a role in the early innate immune response of the corneal resistance against fungus.

7. Induction of Mincle by Helicobacter pylori and consequent anti-inflammatory signaling denote a bacterial survival strategy.

8. our findings identify mincle as a contributor to the inflammatory response after traumatic brain injury

9. Data indicate that MINCLE receptor is able to mediate the response to trehalose-6,6-dimycolate (TDM) dependent on SYK (Montrer SYK Kits ELISA) kinase and CARD9 (Montrer CARD9 Kits ELISA) protein.

10. mincle is a fungal receptor that can suppress antifungal immunity and, as such, is a potential therapeutic target.

Mouse (Murine) C-Type Lectin Domain Family 4, Member E (CLEC4E) interaction partners

1. this study shows that mincle inhibits neutrophils and macrophages apoptosis in Aspergillus fumigatus keratitis

2. Mincle is induced specifically on M1 macrophages, where Mincle-Syk (Montrer SYK Kits ELISA) signaling promotes and maintains inflammatory phenotypes of M1 macrophages in acute renal inflammation.

3. work implicates a novel innate immune driver of Con (Montrer KITLG Kits ELISA) A hepatitis and, more broadly, suggests a potential role for Mincle in diseases governed by sterile inflammation.

4. Mincle deletion results in TLR4 (Montrer TLR4 Kits ELISA)-mediated inflammation.

5. Priming by Mincle-deficient dendritic cells (DCs).

6. Thus, macrophage activation by the corynebacterial cell wall relies on TLR2-driven robust Mincle expression and the cooperative action of both receptors.

7. this study shows that immune activation in vitro and in vivo by trehalose esters of simple fatty acids requires two acyl chains of length and involves Mincle

8. Attenuated neutrophil extracellular trap formation in Mincle-/- neutrophils correlates with impaired autophagy activation in vitro and in vivo, whereas reactive oxygen species formation in these neutrophils remained intact.

9. We here show that Mincle gene expression was induced in alveolar macrophages and neutrophils in bronchoalveolar lavage fluids of mice and patients with pneumococcal pneumonia

10. this study shows a significant role for Mincle in Pneumocystis modulating host defense during infection

Cow (Bovine) C-Type Lectin Domain Family 4, Member E (CLEC4E) interaction partners

1. The structure of an extended portion of the extracellular domain of mincle, beyond the minimal C-type carbohydrate recognition domain, also constrains the way the binding domains may interact on the surface of macrophages.

2. The data demonstrate how mincle bridges between the surfaces of the macrophage and the mycobacterium.

Guinea Pig C-Type Lectin Domain Family 4, Member E (CLEC4E) interaction partners

1. the function of the guinea pig homologue of Mincle (gpMincle) and MCL (Montrer CLEC4D Kits ELISA) (gpMCL). gpMincle directly bound to trehalose-6,6'-dimycolate