C-Type Lectin Domain Family 5, Member A (CLEC5A) Kits ELISA

CLEC5A encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. De plus, nous expédions CLEC5A Anticorps (41) et CLEC5A Protéines (12) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
CLEC5A 23601 Q9NY25
CLEC5A 23845 Q9R007
Anti-Rat CLEC5A CLEC5A 679787  
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Top CLEC5A Kits ELISA sur anticorps-enligne.fr

Showing 3 out of 5 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain 7 pg/mL 28-1800 pg/mL Typical standard curve 96 Tests 15 to 18 Days
$910.56
Détails
Souris 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests 15 to 18 Days
$910.56
Détails
Humain
  96 Tests 26 to 36 Days
$899.80
Détails

Plus Kits ELISA pour CLEC5A partenaires d'interaction

Human C-Type Lectin Domain Family 5, Member A (CLEC5A) interaction partners

  1. CLEC5A was highly upregulated in glioblastoma compared to normal brain tissues, which had an opposite relation with the overall patient survival. Downregulation of CLEC5A could inhibit cell proliferation, migration and invasion via promoting apoptosis and G1 arrest.

  2. MDL-1 is mainly expressed in atherosclerotic lesional macrophages and increased macrophage MDL-1 expression is associated with early plaque progression and promotes macrophage survival.

  3. this study shows association of rs1285933 single nucleotide polymorphism in CLEC5A gene with dengue severity

  4. CLEC5A is critical for dengue virus-induced osteoclast activation and bone homeostasis

  5. Mannose Receptor and CLEC5A on Macrophage first attracts the Dengue Virus with high avidity, and the virus concurrently interacts with CLEC5A in close proximity to form a multivalent hetero-complex and facilitate CLEC5A-mediated signal transduction. Dengue Virus Infection Is through a Cooperative Interaction between a Mannose Receptor and CLEC5A on Macrophage as a Multivalent Hetero-Complex.

  6. The results suggest that CLEC5A-mediated enhancement of the inflammatory response in myeloid cells contributes to influenza pathogenicity in vivo and may be considered a therapeutic target in combination with effective antivirals.

  7. Concordant overexpression of MDL-1 and DAP12 were correlated with increased production of proinflammatory cytokines in rheumatoid arthritis patients.

  8. Blockade of CLEC5A inhibits NLRP3 inflammasome activation and pyrotopsis in dengue-virus-infected inflammatory macrophages. Thus, DV can activate NLRP3 inflammasome via CLEC5A.

  9. No significant associations were noted between the genotypes and allele frequency of the 4 CLEC5A tSNPs between controls and Kawasaki disease patients.

  10. CLEC5A is homodimeric at the cell surface and binds to dengue virus serotypes 1-4.

  11. CLEC5A expression in monocyte/macrophage and granulocytes is regulated by PU.1.

  12. The crystal volume per unit weight (VM) was calculated to be 2.34 A3 Da-1, with nine molecules per asymmetric unit and a solvent content of 47.38%. CLEC5A plays an important role in the pathophysiology of dengue-virus-induced disease.

  13. blockade of CLEC5A-mediated signalling attenuates the production of proinflammatory cytokines by macrophages infected with Dengue virus (either alone or complexed with an enhancing antibody)

Mouse (Murine) C-Type Lectin Domain Family 5, Member A (CLEC5A) interaction partners

  1. MDL-1 is mainly expressed in atherosclerotic lesional macrophages and increased macrophage MDL-1 expression is associated with early plaque progression and promotes macrophage survival.

  2. CLEC5A is critical for dengue virus-induced osteoclast activation and bone homeostasis

  3. Data show that C-type lectin member 5A (CLEC5A) is needed for optimal reactive oxygen species (ROS) production, neutrophil extracellular traps (NETs) formation and other immune responses to Listeria monocytogenes in mice.

  4. The results suggest that CLEC5A-mediated enhancement of the inflammatory response in myeloid cells contributes to influenza pathogenicity in vivo and may be considered a therapeutic target in combination with effective antivirals.

  5. cigarette smoke-induced macrophage responsiveness is mediated by CLEC5A, and CLEC5A is required for the development of inflammation, proinflammatory cytokine expression, and airspace enlargement.

  6. Japanese encephalitis virus (JEV) directly interacts with CLEC5A and induces DAP12 phosphorylation in macrophages.

  7. triggering of MDL-1 on immature myeloid cells and production of NO and TNF-alpha may play a critical role in the pathogenesis of shock

  8. This is the first report that shows the involvement of monocyte and macrophage receptor CLEC5A in severe inflammatory response in Japanese encephalitis virus (JEV) infection of brain.

  9. Activation of MDL-1 leads to enhanced recruitment of inflammatory macrophages and neutrophils to the joint and promotes bone erosion.

  10. MDL-1 plays an important role in immune defense as a result of an innate immunity, which involves neutrophils and macrophages

  11. binding of Dengue virus to macrophages expressing Clec5 initiates cytokine storm pathology

  12. MDL-1 associates with both DAP12 and DAP10 in osteoclasts and bone marrow-derived macrophages, where DAP10 association depends almost entirely on DAP12, suggesting a formation of MDL-1-DAP12/DAP10 trimolecular complexes.

CLEC5A profil antigène

Antigen Summary

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein interacts with dnax-activation protein 12 and may play a role in cell activation. Alternative splice variants have been described but their full-length sequence has not been determined.

Gene names and symbols associated with CLEC5A

  • C-type lectin domain containing 5A (CLEC5A) anticorps
  • C-type lectin domain family 5, member a (Clec5a) anticorps
  • C-type lectin domain containing 5A (Clec5a) anticorps
  • Clecsf5 anticorps
  • Ly100 anticorps
  • MDL-1 anticorps
  • Mdl1 anticorps

Protein level used designations for CLEC5A

C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5 , C-type lectin domain family 5 member A , C-type lectin superfamily member 5 , myeloid DAP12-associating lectin 1 , myeloid DAP12-associating lectin-1 , MDL-1 , myeloid DAP12-associating lectin long form , type II transmembrane protein MDL-1

GENE ID SPECIES
23601 Homo sapiens
397050 Sus scrofa
615201 Bos taurus
23845 Mus musculus
679787 Rattus norvegicus
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