Cell Division Cycle Associated 7-Like (CDCA7L) Kits ELISA

Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. De plus, nous expédions Cell Division Cycle Associated 7-Like Anticorps (50) et Cell Division Cycle Associated 7-Like Protéines (4) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
CDCA7L 217946 Q922M5
CDCA7L 619566 Q4G059
CDCA7L 55536 Q96GN5
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Top Cell Division Cycle Associated 7-Like Kits ELISA sur anticorps-enligne.fr

Showing 3 out of 6 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Souris < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests 11 to 18 Days
$838.60
Détails
Humain < 0.188 ng/mL 0.313 ng/mL - 20 ng/mL   96 Tests 11 to 18 Days
$838.60
Détails
Rat < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests 11 to 18 Days
$838.60
Détails

Plus Kits ELISA pour Cell Division Cycle Associated 7-Like partenaires d'interaction

Mouse (Murine) Cell Division Cycle Associated 7-Like (CDCA7L) interaction partners

  1. Mouse JPO2/RAM2 (Cdca7l) interacts with cMyc.

Human Cell Division Cycle Associated 7-Like (CDCA7L) interaction partners

  1. CDCA7L is highly expressed in human glioma tissues and a high CDCA7L expression level predicts the dismal prognosis for glioma patients

  2. Suppression of CDCA7L limits multiple myeloma proliferation through apoptosis.

  3. We identify the Myc-interacting protein JPO2 and its partner binding protein LEDGF/p75 as critical modulators of PI3K/AKT signaling and metastasis in medulloblastoma

  4. common LEDGF/p75 interaction interface shared by JPO2, PogZ, MLL1, IWS1 and HIV IN

  5. The data are consistent with the rs4487645-CDCA7L loci being responsible for the chromosome 7p11.2 association with multiple myeloma risk, probably exerting its effects through an extended pathway involving IRF4 and MYC.

  6. Data indicate that JPO2 and LEDGF/p75 interact directly and specifically in vivo through the specific interaction domain of JPO2 and the C-terminal domain of LEDGF/p75.

  7. CDCA7L was able to activate the extracellular signal-regulated kinase 1/2 (ERK1/2) signaling pathway and regulate the cell cycle, thus promoting HCC progression.

  8. Reduction in R1 repressor protein correlates significantly with an increase (approximately 40%) in monoamine oxidase A protein levels within the major depressive disorder groups compared with controls.

  9. monoamine oxidase A activation of glucocorticoids and androgens is regulated differently by R1 and Sp1

  10. demonstrates the functions of MAO A and its repressor R1(RAM2/CDCA7L/JPO2) in apoptotic signaling pathways

  11. Over-expression of JPO2 resulted in a modest but reproducible inhibition of HIV-1 replication, consistent with competition between integrase and JPO2 for binding to LEDGF/p75

Cell Division Cycle Associated 7-Like (CDCA7L) profil antigène

Antigen Summary

Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Play an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways\; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1 (By similarity).

Gene names and symbols associated with CDCA7L

  • cell division cycle associated 7 like (CDCA7L) anticorps
  • cell division cycle associated 7 like L homeolog (cdca7l.L) anticorps
  • cell division cycle-associated 7-like protein (LOC100454683) anticorps
  • cell division cycle associated 7 like (Cdca7l) anticorps
  • BC006933 anticorps
  • JPO2 anticorps
  • MGC154777 anticorps
  • R1 anticorps
  • RAM2 anticorps
  • RAPGEF5 anticorps

Protein level used designations for CDCA7L

cell division cycle associated 7-like , transcription factor RAM2 , cell division cycle-associated 7-like protein-like , cell division cycle-associated 7-like protein , Rap guanine nucleotide exchange factor (GEF) 5

GENE ID SPECIES
100067524 Equus caballus
472306 Pan troglodytes
711948 Macaca mulatta
779344 Xenopus laevis
100348574 Oryctolagus cuniculus
100394869 Callithrix jacchus
100454683 Pongo abelii
100472794 Ailuropoda melanoleuca
100585065 Nomascus leucogenys
217946 Mus musculus
619566 Rattus norvegicus
55536 Homo sapiens
420608 Gallus gallus
482347 Canis lupus familiaris
100518624 Sus scrofa
514631 Bos taurus
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