anti-Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) Anticorps

CYP2E1 encodes a member of the cytochrome P450 superfamily of enzymes.

afficher tous les anticorps Gène GeneID UniProt
Anti-Humain CYP2E1 CYP2E1 1571 P05181
Anti-Souris CYP2E1 CYP2E1 13106 Q05421
Anti-Rat CYP2E1 CYP2E1 25086 P05182
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Top anti-Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 199 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB Host:  Rabbit  Target Name:  CYP2E1  Sample Tissue:  Human Fetal Lung  Antibody Dilution:  1.0ug/ml 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 4 to 6 Days
$240.00
Détails
Souris Lapin Inconjugué IHC (p), WB Anti-Cytochrome P450 2E1 antibody, Western blotting Lane 1: Rat Liver Tissue Lysate Lane 2: Mouse Liver Tissue Lysate Anti-Cytochrome P450 2E1 antibody, IHC(P) IHC(P): Rat Liver Tissue 100 μg Connectez-vous pour afficher 4 to 6 Days
$280.00
Détails
Humain Lapin Inconjugué IHC (p), WB Anti- CYP2E1 antibody, IHC(P) IHC(P): Rat Liver Tissue 100 μg Connectez-vous pour afficher 4 to 6 Days
$280.00
Détails
Humain Lapin Inconjugué IHC (p), WB   100 μg Connectez-vous pour afficher 4 to 6 Days
$240.00
Détails
Chien Lapin Inconjugué IC, IF, WB Immunofluorescent analysis of Cytochrome P450 2E1 staining in NIH3T3 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of Cytochrome P450 2E1 expression in HEK293T (A), NIH3T3 (B), H9C2 (C), Human Liver (D) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Cytochrome P450 2E1 Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of HepG2 cells, using Cytochrome P450 2E1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB Western Blot: Cytochrome P450 2E1 Antibody [NBP1-85367] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted) Western Blot: Cytochrome P450 2E1 Antibody [NBP1-85367] - Lane 1: Mouse liver tissue lysate.Lane 2: Rat liver tissue lysate 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB Immunohistochemistry-Paraffin: Cytochrome P450 2E1 Antibody [NBP1-85366] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes. Western Blot: Cytochrome P450 2E1 Antibody [NBP1-85366] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted).Lane 5: Human liver tissue 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Rat Lapin Inconjugué ICC, IHC, WB Western Blot; Sample: Rat Liver lysate; Primary Ab: 3µg/ml Rabbit Anti-Rat CYP2E1 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Connectez-vous pour afficher 15 to 18 Days
$342.00
Détails

anti-Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 Anticorps mieux référencés

  1. Human Polyclonal CYP2E1 Primary Antibody pour IHC (p), WB - ABIN3043821 : Fan, Jiang, Wang, Tan, Zeng, Wang, Chen, Qu, Gonzalez, Huang, Bi: Wuzhi tablet (Schisandra Sphenanthera extract) protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of NRF2-ARE and p53/p21 pathways. dans Drug metabolism and disposition: the biological fate of chemicals 2014 (PubMed)
    Show all 3 Pubmed References

  2. Mouse (Murine) Polyclonal CYP2E1 Primary Antibody pour IHC (p), WB - ABIN3044118 : Jiang, Fan, Wang, Chen, Zeng, Tan, Gonzalez, Huang, Bi: Schisandrol B protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of liver regeneration. dans Toxicological sciences : an official journal of the Society of Toxicology 2014 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal CYP2E1 Primary Antibody pour WB - ABIN3043000 : Chen, Sun, Han, Peng, Li, Liu, Lv, Liu, Zhou, Sun: Protective effect of tea polyphenols against paracetamol-induced hepatotoxicity in mice is significantly correlated with cytochrome P450 suppression. dans World journal of gastroenterology 2009 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal CYP2E1 Primary Antibody pour WB - ABIN514837 : De Bock, Colin, Boussery, Van Bocxlaer: Quantification of cytochrome 2E1 in human liver microsomes using a validated indirect ELISA. dans Journal of pharmaceutical and biomedical analysis 2013 (PubMed)

  5. Human Polyclonal CYP2E1 Primary Antibody pour IF (p), IHC (p) - ABIN707141 : Iwao, Ojima, Kobayashi, Kishi, Nara, Esaki, Shimada, Hiraoka, Tanabe, Kanai: Liver atrophy after percutaneous transhepatic portal embolization occurs in two histological phases: Hepatocellular atrophy followed by apoptosis. dans World journal of hepatology 2017 (PubMed)

  6. Human Polyclonal CYP2E1 Primary Antibody pour IHC, IHC (p) - ABIN4302106 : Hou, Bukong, Kodys, Szabo: Alcohol facilitates HCV RNA replication via up-regulation of miR-122 expression and inhibition of cyclin G1 in human hepatoma cells. dans Alcoholism, clinical and experimental research 2013 (PubMed)

  7. Human Polyclonal CYP2E1 Primary Antibody pour IHC, IHC (p) - ABIN4302104 : Fagerberg, Hallström, Oksvold, Kampf, Djureinovic, Odeberg, Habuka, Tahmasebpoor, Danielsson, Edlund, Asplund, Sjöstedt, Lundberg, Szigyarto, Skogs, Takanen, Berling, Tegel, Mulder, Nilsson, Schwenk et al.: Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics. ... dans Molecular & cellular proteomics : MCP 2014 (PubMed)

  8. Human Polyclonal CYP2E1 Primary Antibody pour ELISA, IHC - ABIN4302103 : Niu, Yuan, Leng, Pang, Gu, Chen: CYP2E1 Rsa I/Pst I polymorphism and esophageal cancer risk: a meta-analysis based on 1,088 cases and 2,238 controls. dans Medical oncology (Northwood, London, England) 2011 (PubMed)

Plus d’anticorps contre Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 partenaires d’interaction

Rabbit Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) interaction partners

  1. The localization of CYP1A2 (Montrer CYP1A2 Anticorps), CYP2B4 and CYP2E1 within the ER was determined by partial membrane solubilization with Brij 98

Guinea Pig Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) interaction partners

  1. Cytochrome P450 2E1 takes part in the pathogenesis of experimental metabolic syndrome in guinea pigs.

Human Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) interaction partners

  1. Report CYP2E1 inhibitory capacity of diallyl sulfide (Montrer SQRDL Anticorps) analogs and roles in reducing ethanol- and acetaminophen-induced toxicity in hepatocytes.

  2. CYP2E1 role in actiavation of the polychlorinated biphenyls mutagens

  3. Case-control study found a significant difference was observed between large artery atherosclerotic ischemic stroke patients and controls with respect to the CYP2E1*5B genotype and allele distribution. NQO1 (Montrer NQO1 Anticorps)*2 polymorphism genotype distribution was significantly different between patients and controls and heterozygote *1*2 genotype was found to be a protective factor against large artery atherosclerotic ischemic stroke.

  4. The observations of the present study give rise to useful information on CYP2E1 polymorphisms in Chinese Uygur individuals.

  5. results provide new information regarding CYP2E1 genetic polymorphisms in Chinese Tibetan population. These findings in this study would be value for further study in assessing the susceptibility of different populations to diseases related to CYP2E1 polymorphisms and determining whether it is necessary to design different therapeutics and toxicological protocols to reduce the risk of population, including pharmacogenetic

  6. Clomethiazole is a direct inhibitor of human CYP2E1 when coincubated with the probe substrate chlorzoxazone.

  7. Methodology to assay CYP2E1 mixed function oxidase catalytic activity and its induction.

  8. Polymorphisms in the promoter region of the CYP2E1 gene were associated with DNA damage in alcoholics.

  9. We identified an exposure-associated differentially methylated region (DMR (Montrer WDR20 Anticorps)) spanning nine sequential CpG sites in the promoter-regulatory region of the cytochrome P450 2E1 gene (CYP2E1) on chromosome 10 (corrected P=2.98 x 10(-5)). Elevated DNA methylation (Montrer HELLS Anticorps) across this region was also associated with deprivation-related clinical markers of impaired social cognition.

  10. A significant increase in the risk of non-small cell lung cancer was observed for the following combinations: TP53 (Montrer TP53 Anticorps) codon72 variant with GSTM1 (Montrer GSTM1 Anticorps) null (OR 2.22, 95 % CI 1.23-4.04; p=0.009), GSTT1 (Montrer GSTT1 Anticorps) null (OR 2.98, 95 % CI 1.49-5.94; p=0.002), and GSTP1 (Montrer GSTP1 Anticorps) (Ala114Val) variant genotypes (OR 3.38, 95 % CI 1.54-7.41; p=0.002).

Mouse (Murine) Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) interaction partners

  1. BI-1 protects against obesity-induced hepatic insulin (Montrer INS Anticorps) resistance by regulating CYP2E1 activity and reactive oxygen species production.

  2. Baicalin inhibited ethanol-induced expression of reactive oxygen species (ROS (Montrer ROS1 Anticorps)) generating enzymes NOX2 (Montrer CYBB Anticorps), p67phox (Montrer NCF2 Anticorps), xanthine oxidase (Montrer XDH Anticorps), and iNOS (Montrer NOS2 Anticorps) in addition to CYP2E1 activities.

  3. Methodology to assay CYP2E1 mixed function oxidase catalytic activity and its induction/

  4. we show that TRPV4 (Montrer TRPV4 Anticorps) is activated both by damage associated molecular pattern HMGB1 (Montrer HMGB1 Anticorps) and collagen in diseased Kupffer cells that in turn activate the endothelial NOS (NOS3 (Montrer NOS3 Anticorps)) to release nitric oxide (NO). The diffusible NO acts in a paracrine fashion in neighboring hepatocytes to deactivate the redox toxicity induced by CYP2E1

  5. Data, including data from studies in knockout mice, suggest that the oxidative metabolism of 1,2-dichloropropane, a carcinogenic solvent/insecticide, is exclusively catalyzed by Cyp2e1; this biotransformation step is indispensable for manifestation of hepatotoxic effect of the solvent.

  6. Taken together, these results suggested that 1,2-dichloroethane (1,2-DCE (Montrer DHCR24 Anticorps)) could enhance CYP2E1 protein expression and enzymatic activity, which could cause oxidative damage in liver, serving as an important mechanism underlying 1,2-DCE (Montrer DHCR24 Anticorps)-induced liver damage

  7. CYP2E1 is important in causing aging-dependent hepatic steatosis, apoptosis and fibrosis possibly through increasing nitroxidative stress.

  8. Our results support a significant role for CYP2E1 as a novel 4-Aminobiphenyl N-oxidizing enzyme in adult mice

  9. Schisandrol B protects against APAP-induced liver injury, potentially through inhibition of CYP2E1/3A11-mediated APAP bioactivation and regulation of the p53 (Montrer TP53 Anticorps), p21 (Montrer D4S234E Anticorps), CCND1 (Montrer CCND1 Anticorps), PCNA (Montrer PCNA Anticorps), and BCL-2 (Montrer BCL2 Anticorps) to promote liver regeneration.

  10. Studied hepatic stellate cell cytoglobin (Montrer CYGB Anticorps) involvement in acetaminophen induced hepatotoxicity through the regulation of CYP2E1.

Pig (Porcine) Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) interaction partners

  1. A highly significant association was found between variation in skatole levels and SNPs within the CYP2E1 gene on chromosome 14.

  2. The relationship between a single nucleotide polymorphism of CYP2E1 and boar taint in pork from Belgian swine is reported.

Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) profil antigène

Profil protéine

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.

Gene names and symbols associated with CYP2E1

  • cytochrome P450, family 2, subfamily E, polypeptide 1 (CYP2E1) anticorps
  • cytochrome P450 2E1 (CYP2E1) anticorps
  • cytochrome P450 2E1 (PTRG_07411) anticorps
  • cytochrome P450 2E1 (LOC100342572) anticorps
  • cytochrome P450 2E1 (LOC100727914) anticorps
  • cytochrome P450 2E1-like (LOC101843716) anticorps
  • cytochrome P450 family 2 subfamily E member 1 (CYP2E1) anticorps
  • cytochrome P450, family 2, subfamily e, polypeptide 1 (Cyp2e1) anticorps
  • CPE1 anticorps
  • Cyp2e anticorps
  • CYP2E1 anticorps
  • CYPIIE1 anticorps
  • P450-J anticorps
  • P450C2E anticorps

Protein level used designations for CYP2E1

cytochrome P450 2E1 , 4-nitrophenol 2-hydroxylase , Cytochrome P450 2E1 , Cytochrome P450 LM3A , Cytochrome P450 isozyme 3A , Cytochrome P450-ALC , Cytochrome P450-J , cytochrome P-450j , CYPIIE1 , cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1 , cytochrome P450-J , flavoprotein-linked monooxygenase , microsomal monooxygenase , xenobiotic monooxygenase , cytochrome P450, 2e1, ethanol inducible , cytochrome P450-ALC , P450-J , P450RLM6 , cytochrome P450 subfamily 2e1 (ethanol-inducible) , cytochrome P450, subfamily 2E, polypeptide 1 , cytochrome P450RLM6 , cytochrome P-450-J , cytochrome P450 CYP2E1

GENE ID SPECIES
100066422 Equus caballus
554344 Felis catus
6345684 Pyrenophora tritici-repentis Pt-1C-BFP
100342572 Oryctolagus cuniculus
100727914 Cavia porcellus
101843716 Mesocricetus auratus
1571 Homo sapiens
415128 Canis lupus familiaris
13106 Mus musculus
25086 Rattus norvegicus
403216 Sus scrofa
282213 Bos taurus
100568285 Ovis aries
678688 Macaca mulatta
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