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Translation factor necessary for the incorporation of selenocysteine into proteins. De plus, nous expédions Eukaryotic Elongation Factor, Selenocysteine-tRNA-Specific Protéines (2) et beaucoup plus de produits pour cette protéine.
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eEFSec employs a non-canonical mechanism involving the distinct C-terminal domain 4 for the release of the selenocysteinyl-tRNA during decoding on the ribosome
In this genomewide association study, we found that variants at the EBF1, EEFSEC, AGTR2, WNT4, ADCY5, and RAP2C loci were associated with gestational duration and variants at the EBF1, EEFSEC, and AGTR2 loci with preterm birth.
SECIS binding induces a conformational change in SBP2 that recruits eEFSec, which in concert with the Sec incorporation domain gains access to the ribosomal A site
This study examined the subcellular localization of eEFSec in the context of altered Selenocysteine incorporation to demonstrate that reduced selenoprotein production does not correlate with changes in the nuclear localization of eEFSec.
SBP2/SECIS complex activates eEFSec by directing functional interactions between Domain IV and the ribosome to promote Sec-tRNA(Sec) binding and accommodation into the ribosomal A-site
Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.
selenocysteine-specific elongation factor
, elongation factor for selenoprotein translation
, elongation factor sec
, MJ0495-like protein SelB