anti-Fat Mass and Obesity-Associated (FTO) Anticorps

FTO is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of FTO is not known. De plus, nous expédions FTO Protéines (10) et FTO Kits (9) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
FTO 79068 Q9C0B1
FTO 26383 Q8BGW1
FTO 291905 Q2A121
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Top anti-FTO Anticorps sur anticorps-enligne.fr

Showing 10 out of 144 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Chien Lapin Inconjugué WB <b>WB Suggested Anti-FTO Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>PANC1 cell lysate WB Suggested Anti-FTO <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500 <br /> Positive Control: PANC1 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-Fto Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Mouse Brain WB Suggested Anti-Fto <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: Mouse Brain 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB Western blot analysis of FTO expression in HepG2 (A), Caco2 (B), SHSY5Y (C) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Chèvre Inconjugué ELISA, WB ABIN308414 (0.03µg/ml) staining of Human Pancreas lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Connectez-vous pour afficher 6 to 7 Days
$358.02
Détails
Humain Lapin Inconjugué FACS, IHC, WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$245.00
Détails
Humain Lapin Inconjugué EIA, WB Western blot analysis of FTO Antibody (N-term) in NCI-H460 cell line lysates (35 µg/lane). FTO (arrow) was detected using the purified Pab. 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Humain Lapin Inconjugué WB Detection of FTO in human brain lysate using ABIN258809. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$444.19
Détails
Humain Chèvre Inconjugué ELISA, WB 100 μg Connectez-vous pour afficher 7 to 9 Days
$610.50
Détails
Boeuf (Vache) Lapin Inconjugué IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 7 to 9 Days
$727.83
Détails
Humain Lapin Inconjugué FACS, IHC (p), WB Western blot analysis of FTO Antibody (N-term) (ABIN390964) in NCI-H460 cell line lysates (35 µg/lane). FTO (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with FTO Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails

FTO Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-FTO Anticorps mieux référencés

  1. Human Polyclonal FTO Primary Antibody pour ELISA, WB - ABIN316349 : Gerken, Girard, Tung, Webby, Saudek, Hewitson, Yeo, McDonough, Cunliffe, McNeill, Galvanovskis, Rorsman, Robins, Prieur, Coll, Ma, Jovanovic, Farooqi, Sedgwick, Barroso, Lindahl, Ponting, Ashcroft et al.: The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. ... dans Science (New York, N.Y.) 2007 (PubMed)

  2. Human Polyclonal FTO Primary Antibody pour WB - ABIN258809 : Walters, Mercaldo, Gillon, Yip, Neve, Boyce, Frankland, Josselyn: The Role of The RNA Demethylase FTO (Fat Mass and Obesity-Associated) and mRNA Methylation in Hippocampal Memory Formation. dans Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2017 (PubMed)

Plus d’anticorps contre FTO partenaires d’interaction

Human Fat Mass and Obesity-Associated (FTO) interaction partners

  1. The aggregation analysis revealed a higher correlation between siblings than between parent-offspring pairs representing the role of genetic factors in metabolic syndrome (MetS (Montrer ETV3 Anticorps)). In addition, the conditional logistic model with covariates showed that the linkage results between HDL_C and three markers, FTO (rs1558902 and rs7202116) and CETP (Montrer CETP Anticorps)(rs1864163) were significant.

  2. genetic association studies in population of adolescents in the United States: Data suggest that an SNP in FTO (rs9939609) is associated with adolescent overweight/obesity and obesogenic appetitive traits (decreased satiety responsiveness and increased food responsiveness) in the population studied.

  3. This meta-analysis provides additional support for a significant interaction between FTO, depression and BMI, indicating that depression increases the effect of FTO on BMI.

  4. children at risk for obesity possessing the obesity risk polymorphism (FTO rs9939609) exhibited stronger responses to food commercials in the nucleus accumbens (NAcc) than children not at risk. Similarly, children at a higher genetic risk for obesity possessing the obesity risk polymorphism (FTO rs9939609) demonstrated larger NAcc volumes.

  5. Variations within FTO may be predictors of fatty liver disease in HIV-infected patients independently of metabolic factors.

  6. N(6)-Methyladenosine itself serves as a 'conformational marker', which induces different conformational outcomes in RNAs depending on sequence context. This critically impacts its interactions with several m6A (Montrer GPM6A Anticorps)-recognising proteins, including FTO and ALKBH5 (Montrer ALKBH5 Anticorps).

  7. Studied weight loss in obese patients with Perilipin 4 (PLIN4 (Montrer PLIN4 Anticorps)), Fat mass and obesity-associated (FTO), and beta- adrenergic receptor 3 (ADRB3 (Montrer ADRB3 Anticorps)) polymorphisms treated with Garcinia cambogia/Glucomannan. Results suggest weight loss was attenuated in carriers of PLIN4 (Montrer PLIN4 Anticorps), FTO, ADRB3 (Montrer ADRB3 Anticorps) polymorphisms.

  8. Fat mass and obesity associated (FTO) was the first gene found to be associated with obesity in three independent genome-wide association studies.

  9. It has been shown, that presence of one mutant allele of rs9939609 (gene FTO) and rs4994 (gene ADRB3 (Montrer ADRB3 Anticorps)) leads to statistically significant association with obesity.

  10. Food advertisement exposure was associated with greater caloric consumption of a recently advertised food, and this effect was modified by an FTO genotype. Future research is needed to understand the neurological mechanism underlying these associations.

Mouse (Murine) Fat Mass and Obesity-Associated (FTO) interaction partners

  1. FTO demethylase (Montrer MBD2 Anticorps) activity is essential for normal bone development and mineralization, a previously unreported FTO function.

  2. FTO is critically involved in insulin (Montrer INS Anticorps) defects-related Alzheimer's disease.

  3. This is the first study revealing the presence of a parallel increase in expressions of FTO and HNRNPK (Montrer HNRNPK Anticorps) proteins. This increase may codictate the metabolic changes occurring in the cell and may attribute a significance to HNRNPK (Montrer HNRNPK Anticorps) in FTO-associated transformations.

  4. Contextual fear conditioning decreased FTO levels in neurons from the hippocampus.

  5. The involvement of mTOR (Montrer FRAP1 Anticorps)-PGC-1alpha pathway in the connection between FTO and muscle differentiation is displayed.

  6. In vivo experiments revealed that Fto(-/-) and Fto(+/-) mice were more susceptible to thiopurine-induced myelosuppression than wild-type mice.

  7. propose that PKCbeta acts to suppress the degradation of FTO protein and reveals the associated role of PKCbeta and FTO in adipogenesis, suggesting a new pathway that affects the development of obesity and metabolic diseases

  8. the results of this study indicate that the effects of FTO-associated SNPs on energy homeostasis are due in part to the effects of these genetic variations on hypothalamic FTO, RPGRIP1L (Montrer RPGRIP1L Anticorps), and possibly other genes.

  9. FTO may have a deleterious role in hepatic cells during lipotoxic conditions, and up-regulation of FTO may contribute to the increased liver damage in non-alcoholic steatohepatitis

  10. Fto deficiency affects the gene and miR130/miR378 expression involved in brown adipogenesis and browning of white adipose tissue in mice.

Pig (Porcine) Fat Mass and Obesity-Associated (FTO) interaction partners

  1. In this study, the authors characterise the nucleotide variability and haplotype diversity of the porcine fat mass and obesity-associated (FTO) gene in breeds having different predispositions to fat deposition traits.

  2. In pig, the FTO gene influences back fat depth in the commercial populations.

  3. This study will provide clues for obtaining a better understanding of the porcine FTO gene function.

  4. The results of the association analyses confirmed the effect of the FTO mutation on obesity-related traits in the Italian Duroc pigs (P < 0.01) and in the commercial pigs.

  5. The porcine fat mass and obesity associated (FTO) gene is associated with fat deposition in Italian Duroc pigs.

Cow (Bovine) Fat Mass and Obesity-Associated (FTO) interaction partners

  1. 34 FTO polymorphisms revealed significant association of FTO variants with lean meat percentage in Simmental and Brown cattle breeds.

  2. association signals not only provided evidence for at least two causative mutations in the FTO locus with a functional effect on milk but also milk protein (Montrer CSN2 Anticorps) yield

  3. Haplotype frequencies and linkage disequilibrium (LD) coefficients of FTO single nucleotide polymorphisms in three Chinese indigenous cattle breeds were analyzed.

FTO profil antigène

Profil protéine

This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

Gene names and symbols associated with FTO

  • FTO, alpha-ketoglutarate dependent dioxygenase (FTO) anticorps
  • fat mass and obesity associated (Fto) anticorps
  • FTO, alpha-ketoglutarate dependent dioxygenase (Fto) anticorps
  • fat mass and obesity associated L homeolog (fto.L) anticorps
  • AW743446 anticorps
  • mKIAA1752 anticorps
  • RGD1305121 anticorps

Protein level used designations for FTO

alpha-ketoglutarate-dependent dioxygenase FTO , fat mass and obesity-associated protein , protein fto , protein fatso , fat mass and obesity associated protein , Protein fatso

GENE ID SPECIES
79068 Homo sapiens
26383 Mus musculus
478125 Canis lupus familiaris
100127165 Sus scrofa
291905 Rattus norvegicus
100060565 Equus caballus
618622 Bos taurus
100125353 Ovis aries
447305 Xenopus laevis
100173222 Pongo abelii
Fournisseurs de qualité sélectionnés pour anti-FTO (FTO) Anticorps
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