anti-Granzyme K (Granzyme 3, Tryptase II) (GZMK) Anticorps

GZMK product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. De plus, nous expédions Granzyme K (Granzyme 3, Tryptase II) Kits (31) et Granzyme K (Granzyme 3, Tryptase II) Protéines (14) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
GZMK 14945 O35205
GZMK 29165 P49864
GZMK 3003 P49863
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Top anti-Granzyme K (Granzyme 3, Tryptase II) Anticorps sur anticorps-enligne.fr

Showing 10 out of 84 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Cheval Lapin Inconjugué WB WB Suggested Anti-GZMK Antibody Titration:  0.2-1 ug/ml  Positive Control:  HepG2 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué WB WB Suggested Anti-GZMK Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Human Spleen 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué ELISA, IF, IHC, WB 100 μL Connectez-vous pour afficher Disponible
$363.46
Détails
Humain Lapin Inconjugué IC, IF, WB   200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Souris Inconjugué cELISA, FACS, ELISA Specificity testing of GM24C3, GM26E7 andGM6C3. BOSC cells weretransiently transfected withexpression vectors for gran-zyme A, B, K and M as well as an irrelevant protein. Ex-pression of the constructs wastested with an anti-tag mono-clonal antibody (B) Intracellular detection of granzyme K in humanPBMC. Mononuclear cells from peripheral blood (PBMC)were seperated by Ficoll-Hypaque, fixed andpermeabilised. Cells were incubated with hybridomasupernatant of GM24C3, GM26E7 or GM6C3for 30minutes. Bound anti 100 μg Connectez-vous pour afficher 6 to 7 Days
$466.13
Détails
Humain Lapin Inconjugué IHC, IHC (p) Immunohistochemistry: Granzyme K Antibody [NBP2-49387] - Staining of human tonsil shows strong positivity in a subset of non-germinal center cells. Immunohistochemistry-Paraffin: Granzyme K Antibody  - Staining of human tonsil shows strong positivity in a subset of non-germinal center cells. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$494.38
Détails
Humain Lapin Inconjugué ELISA, IF, IHC, IHC (p), WB 100 μL Connectez-vous pour afficher 11 to 14 Days
$493.17
Détails
Humain Lapin Inconjugué ICC, IHC, WB Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μg Connectez-vous pour afficher 15 to 18 Days
$332.00
Détails
Souris Lapin Inconjugué ICC, IHC, WB Western Blot; Sample: Mouse Lung lysate; Primary Ab: 2µg/ml Rabbit Anti-Mouse GZMK Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Connectez-vous pour afficher 13 to 16 Days
$342.00
Détails
Humain Souris Inconjugué ICC, IHC (fro), IHC (p), ELISA, WB 200 μg Connectez-vous pour afficher 13 to 16 Days
$352.00
Détails

anti-Granzyme K (Granzyme 3, Tryptase II) Anticorps mieux référencés

  1. Human Monoclonal GZMK Primary Antibody pour EIA, FACS - ABIN5541917 : Bratke, Kuepper, Bade, Virchow, Luttmann: Differential expression of human granzymes A, B, and K in natural killer cells and during CD8+ T cell differentiation in peripheral blood. dans European journal of immunology 2005 (PubMed)

Plus d’anticorps contre Granzyme K (Granzyme 3, Tryptase II) partenaires d’interaction

Mouse (Murine) Granzyme K (Granzyme 3, Tryptase II) (GZMK) interaction partners

  1. these data suggest that granzyme K does not play an essential role in viral immunity or cytotoxicity

  2. Data indicate N-terminomics on the human and mouse granzymes A and K by combined fractional diagonal chromatography (COFRADIC).

  3. The data suggest that T-killer cells control lymphocytic choriomeningitis virus through non-cytotoxic processes that involve gzmK.

  4. It was suggested that a high predisposition to catalepsy in mice can be defined by the Map3k1, Il6st, Gzmk, and Hspb3 genes' coexpression network.

  5. GzmK-induced caspase-independent death occurs through Bid-dependent mitochondrial damage that is different from GzmA

  6. grzK plays an important role in CD8(+) T-cell cytotoxicity both in the presence and absence of grzA and B.

Human Granzyme K (Granzyme 3, Tryptase II) (GZMK) interaction partners

  1. Extracellular granzyme K mediates endothelial activation through the cleavage of PAR-1.

  2. Carbamate pesticides significantly reduced the intracellular levels of perforin, GrA, GrB, Gr3/K, and GRN in NK-92CI cells.

  3. Data indicate N-terminomics on the human and mouse granzymes A and K by combined fractional diagonal chromatography (COFRADIC).

  4. Extracellular GrK is an unexpected direct modulator of lipopolysaccharide-TLR4 signaling during the antimicrobial innate immune response.

  5. Granzyme K plays an important physiological role in immunoregulation of adaptive immunity underlying the cytotoxicity of CD56(bright) natural killer (NK) cells toward activated T cells.

  6. Gr3 proenzymes is activated by cathepsin C which concomitantly decreased the molecular weight to that of active Gr3.

  7. The 2.2-A crystal structure reveals a rigid zymogen with unusual features

  8. The present findings thus introduce the possibility that human beta-tryptase, after mast cell degranulation and exposure to neutral pH in the tissue, may dissociate into active monomers with properties that are distinct from the tetrameric counterpart.

  9. We found human GzmK triggers rapid cell death independently of caspase activation. The features of death are characterized by rapid externalization of phosphatidylserine, nuclear morphological changes and single-stranded DNA nicks.

  10. GzmK-induced caspase-independent death occurs through Bid-dependent mitochondrial damage that is different from GzmA

  11. Rsults indicate that plasma levels of Granzyme K could serve as a useful diagnostic marker to stage sepsis, permitting better classification, specific treatments of patients, and may play a functional role in the development of sepsis.

  12. GrK not only constitutes a redundant functional backup mechanism that assists GrA-induced cell death but that it also displays a unique function by cleaving its own specific substrates.

  13. p53 is as a cytotoxic bomb that can be triggered by granzyme K, leading to potentiating killing efficacy.

Rabbit Granzyme K (Granzyme 3, Tryptase II) (GZMK) interaction partners

  1. Data show that the serum levels of mast cell tryptase, monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8) decreased significantly in Dachengqi decoction treatment group.

Granzyme K (Granzyme 3, Tryptase II) (GZMK) profil antigène

Profil protéine

This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.

Gene names and symbols associated with GZMK

  • granzyme K (GZMK) anticorps
  • granzyme K (Gzmk) anticorps
  • TRYP2 anticorps

Protein level used designations for GZMK

NK-Tryp-2 , NK-tryptase-2 , RNK-Tryp-2 , fragmentin-3 , granzyme 3 , granzyme K , granzyme K (serine protease, granzyme 3; tryptase II) , granzyme-3 , tryptase II

GENE ID SPECIES
100052126 Equus caballus
14945 Mus musculus
29165 Rattus norvegicus
3003 Homo sapiens
100233185 Sus scrofa
426168 Gallus gallus
100727863 Cavia porcellus
100345938 Oryctolagus cuniculus
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