anti-HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1) Anticorps

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. De plus, nous expédions et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
HECW1 23072 Q76N89
Anti-Souris HECW1 HECW1 94253 Q8K4P8
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Top anti-HECW1 Anticorps sur anticorps-enligne.fr

Showing 5 out of 8 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of HECW1 using K562 whole cell lysates 100 μL Connectez-vous pour afficher 11 to 12 Days
$390.77
Détails
Humain Lapin Inconjugué IHC (p) Immunohistochemical staining of human cerebral cortex with HECW1 polyclonal antibody  shows strong nuclear and cytoplasmic positivity in neuronal cells at 1:10-1:20 dilution. 100 μL Connectez-vous pour afficher 11 to 12 Days
$577.33
Détails
Humain Lapin Inconjugué WB Western blot analysis HECW1 using K562 whole cell lysates. 100 μg Connectez-vous pour afficher 11 to 18 Days
$440.62
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p) Immunofluorescence: HECW1 Antibody [NBP1-93645] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli & cytoplasm. Immunohistochemistry-Paraffin: HECW1 Antibody [NBP1-93645] - Immunohistochemical staining of human pancreas shows strong nuclear and cytoplasmic positivity in exocrine glandular cells and islet cells. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$494.38
Détails
Humain Lapin Inconjugué ICC, IF Immunocytochemistry/Immunofluorescence: HECW1 Antibody  - Staining of human cell line A549 shows localization to cytosol. 100 μL Connectez-vous pour afficher 10 to 13 Days
$494.38
Détails

Plus d’anticorps contre HECW1 partenaires d’interaction

Human HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1) interaction partners

  1. Ndel1 acts as a novel upstream regulator of the trichoplein-Aurora A pathway to inhibit primary cilia assembly.

  2. Ndel1 regulates Dyn2 GTPase activity and impacts GluR1-containing membranes distribution in a manner reminiscent of Dyn2.

  3. These findings suggest that the human NEDL1 transgenic mice might develop Amyotrophic lateral sclerosis-like symptoms, showing signs of motor abnormalities, accompanied with significant reduction in muscle strength.

  4. These findings suggest that RNF43 is associated with p53-mediated apoptosis in collaboration with NEDL1 in colorectal carcinogenesis.

  5. interaction among misfolded SOD1, NEDL1, translocon-associated protein-delta, and Dishevelled-1 forms a ubiquitinated protein complex that is included in potentially cytotoxic protein aggregates

  6. functional interaction of NEDL1 with p53 might contribute to the induction of apoptosis in cancerous cells bearing wild-type p53.

Mouse (Murine) HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1) interaction partners

  1. Ndel1 acts as a novel upstream regulator of the trichoplein-Aurora A pathway to inhibit primary cilia assembly.

HECW1 profil antigène

Profil protéine

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.

Gene names and symbols associated with HECW1

  • HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 (HECW1) anticorps
  • HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 (Hecw1) anticorps
  • 9330116H24Rik anticorps
  • AV273951 anticorps
  • E130207I19Rik anticorps
  • Nedl1 anticorps

Protein level used designations for HECW1

E3 ubiquitin-protein ligase HECW1 , HECT type E3 ubiquitin ligase , HECT, C2 and WW domain-containing protein 1 , NEDD4-like E3 ubiquitin-protein ligase 1 , NEDD4-like ubiquitin-protein ligase 1 , mNEDL1

GENE ID SPECIES
23072 Homo sapiens
94253 Mus musculus
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