anti-Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6) Anticorps

In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. De plus, nous expédions HSPA6 Protéines (8) et HSPA6 Kits (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
HSPA6 3310 P17066
HSPA6    
HSPA6    
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Top anti-HSPA6 Anticorps sur anticorps-enligne.fr

Showing 10 out of 69 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué WB WB Suggested Anti-HSPA6 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Transfected 293T 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué ELISA, IHC, WB Western blot analysis of HSPA6 using mouse liver lysates ABIN6278411 at 1/100 staining Human lymph node tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Connectez-vous pour afficher 11 to 12 Days
$390.77
Détails
Humain Souris Inconjugué IF, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HSPA6 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-HSPA6. 0.1 mL Connectez-vous pour afficher 2 to 3 Days
$462.00
Détails
Humain Lapin Inconjugué ICC, IF, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: H1299 7.5% SDS PAGE antibody diluted at 1:1000 IHC-P Image Immunohistochemical analysis of paraffin-embedded SG xenograft, using HSPA6, antibody at 1:500 dilution. 100 μL Connectez-vous pour afficher 3 to 4 Days
$466.18
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Western Blot: HspA6 Antibody [NBP1-85949] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp Immunocytochemistry/Immunofluorescence: HspA6 Antibody [NBP1-85949] - Immunofluorescent staining of human cell line U-251MG shows positivity in nucleus but not nucleoli, cytoplasm & golgi apparatus. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$494.38
Détails
Humain Lapin Inconjugué IHC, WB Western blot analysis of extracts of various cell lines, using HSPA6 antibody. Immunohistochemistry of paraffin-embedded rat brain using HSPA6 antibody at dilution of 1:100 (x40 lens). 100 μL Connectez-vous pour afficher 11 to 13 Days
$366.77
Détails
Humain Lapin Inconjugué FACS, IHC (p), WB Western blot analysis of lysate from Jurkat cell line,using HSPA6 Antibody .AP8708b was diluted at 1:1000 at each lane Formalin-fixed and paraffin-embedded human lung carcinoma reacted with HSPA6 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Connectez-vous pour afficher 2 to 3 Days
$515.63
Détails
Humain Lapin Inconjugué FACS, IHC, WB Western blot analysis of extracts of Jurkat cells, using HSPA6 antibody (ABIN5972099). 100 μL Connectez-vous pour afficher 11 to 16 Days
$412.19
Détails
Humain Souris Inconjugué FACS, IF, WB Anti-HSPA6 mouse monoclonal antibody (ABIN2453153) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY HSPA6 (RC207795). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HSPA6 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-HSPA6. 0.1 mL Connectez-vous pour afficher 2 to 3 Days
$462.00
Détails
Humain Souris Inconjugué FACS, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HSPA6 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-HSPA6. 0.1 mL Connectez-vous pour afficher 2 to 3 Days
$462.00
Détails

anti-HSPA6 Anticorps mieux référencés

  1. Human Polyclonal HSPA6 Primary Antibody pour FACS, IHC (p) - ABIN1881440 : Leung, Hall, Rajendran, Spurr, Lim: The human heat-shock genes HSPA6 and HSPA7 are both expressed and localize to chromosome 1. dans Genomics 1992 (PubMed)

  2. Human Monoclonal HSPA6 Primary Antibody pour IF, WB - ABIN2723106 : Kuballa, Baumann, Mayer, Bär, Burtscher, Brinkmann: Induction of heat shock protein HSPA6 (HSP70B') upon HSP90 inhibition in cancer cell lines. dans FEBS letters 2015 (PubMed)

Plus d’anticorps contre HSPA6 partenaires d’interaction

Pig (Porcine) Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6) interaction partners

  1. HSP70 indirectly interacted with Smad3.

  2. There was a significant decrease in the systemic HSP70 levels of trauma groups (moderate and severe hemorrhage) when compared to the sham trauma group, which was significantly decreased compared to baseline values in severe hemorrhage over the entire time course.

  3. Host HSP70 and Classical swine fever virus NS5A protein complex formation is confirmed by coimmunoprecipitation and GST-pulldown studies.

  4. This study evaluated the expression of 70kDa heat shock proteins and the concentration of thiobarbituric acid reactive substances and nitric oxide ions as markers of oxidative stress in swine.

  5. This study revealed that HSP70 is an essential host factor required for the replication of porcine reproductive and respiratory syndrome virus.

  6. A specific interaction between Hsp70 and porcine circovirus type 2 Cap (capsid protein) was confirmed by colocalization by confocal microscopy and co-immunoprecipitation.

  7. This work investigated the expression of heat shock protein 70 by Western blot in swine liver. Animals in an intensive/indoor confinement system showed significantly higher HSP70 values compared with those in an extensive/outdoor system.

  8. The results indicate that Heat shock protein 70 (Hsp70) mediates distinct stress-related functions in different tissues during transportation. Heat shock factor-1 (HSF-1) levels were reduced at 1 and 4 h only in the hearts of transported pigs.

  9. These results indicated that the expression of Hsp70 in the intestinal piglets was upregulated by IUGR, and different intestinal sites had different responses to stress.

  10. Induction of tolerance to heat shock correlated with the induced expression of heat shock protein 70. HSP70 and compatible osmolytes have distinct roles in cellular adaptation to these stresses.

  11. a parameter of early mRNA expression during intestinal ischemia reperfusion injury

  12. HSP-70 is an endogenous protectant of which its actions may be unmasked and/or potentiated with exogenous administration before brain injury

  13. Data demonstrate that lipopolysaccharides evoke a heat shock response, with an increase heat shock proteins 70 and Hsp32) and of VEGF, a specific endothelial cell growth factor.

  14. Extremely low frequency magnetic field exposure induced an increase in the mRNA levels which was statistically significant for Hsp70.

Human Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6) interaction partners

  1. HSPA6 is a cigarette smoke-induced ulcerative colitis (UC)-susceptibility gene. The HSPA6 risk locus is associated with decreased HSPA6 expression. HSPA6 provides epithelial protection by stabilizing anti-apoptotic Bcl-XL, thereby contributing to the beneficial effect of cigarette smoking in UC.

  2. that HSPA6 and HSPA1A contribute to protection of differentiated human neuronal cells from cellular stress

  3. during recovery from neuronal stress, HSPA6 localized with perispeckles that have been characterized as transcription sites; the stress-induced association of HSPA6 with perispeckles displayed the greatest dynamism compared to the interaction of HSPA6 or HSPA1A with other stress-sensitive cytoplasmic and nuclear structures; this suggests involvement of HSPA6 in recovery of neurons from cellular stress

  4. In vivo efficacy experiments with HSPA6 siRNA and MFH were performed using the A2780cp20 and HeyA8 ovarian cancer mouse models. A significantly reduction in tumor growth rate was observed with combination therapy. PES and MFH efficacy were also evaluated in the HeyA8 intraperitoneal tumor model, and resulted in robust antitumor effects.

  5. measurable HSP70B' was not associated with graft versus host disease following allogeneic hematopoietic cell transplantation

  6. We found that HSF1 activation mediated by 1,4-NQ upregulated downstream genes, such as HSPA6. The results suggest that activation of the HSP90-HSF1 signal transduction pathway mediated by 1,4-NQ protects cells against 1,4-NQ and that per/polysulfides can diminish the reactivity of 1,4-NQ by forming sulfur adducts.

  7. mRNA levels of HSP family members (HSP70B', HSP72, HSP40/DNAJ, and HSP20/CRYAB) are upregulated by the intracellular MMP3 overload.

  8. endothelial nitric oxide synthase induces heat shock protein HSPA6 (HSP70B') in human arterial smooth muscle cells

  9. High BCLC staging scores, advanced cirrhosis and the overexpression of HSPA12A and HSP90B1 might be associated with poor survival from HCC, whereas high levels of HSPA4, HSPA5 and HSPA6 might be associated with earlier recurrence of HCC

  10. Data indicate that heat shock protein 90kD(HSP90) inhibition induces heat shock 70kD protein 6 (HSP70B') expression.

  11. Potential stress-sensitive sites were identified in differentiated human SH-SY5Y cells by the localization of HSPA6 (HSP70B') and HSPA1A (HSP70-1) to nuclear components following heat shock

  12. HSPA6 regulation by TNIP1 occurs in promoter regions lacking binding sites for known TNIP1-repressed transcription factors

  13. Following a brief period of thermal stress, YFP-tagged HSPA6 and HSPA1A rapidly appeared at centrioles in the cytoplasm of human neuronal cells.

  14. Hsp70B' also formed complexes with Hsp40 suggesting a common co-chaperone for HSP70 family members.

  15. Heat shock protein 70B' (HSP70B') expression and release in response to human oxidized low density lipoprotein immune complexes in macrophages.

  16. These findings are likely to be important in pathological conditions in which Hsp70B' contributes to cell survival.

  17. Hsp70B' expressed on colon cells after proteasome inhibition was most closely related to Hsp72. They shared 100% AA identity in the peptide-binding region but differed in the lid and C-terminal domains.Hsp70B' appeared to have diverged recently.

  18. higher expression of HSPA6 & HSPA1A was exhibited in placental vascular disease (PVD)subjects compared to normal pregnancy; significant upregulation of HSP70 mRNA & protein in placental tissue & microvascular endothelial cells of PVD subjects was observed

  19. Hsp70B' and Hsp72 play cooperative roles in cell survival of proteotoxic stress.

HSPA6 profil antigène

Profil protéine

In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage (By similarity).

Gene names and symbols associated with HSPA6

  • heat shock protein family A (Hsp70) member 6 (HSPA6) anticorps
  • HSP70B' anticorps
  • HSPA6 anticorps

Protein level used designations for HSPA6

Heat shock 70 kDa protein 6 , heat shock 70 kDa protein , heat shock 70 kDa protein B' , heat shock 70 kDa protein 6 , heat shock 70kD protein 6 (HSP70B')

GENE ID SPECIES
748740 Pan troglodytes
539835 Bos taurus
396906 Sus scrofa
3310 Homo sapiens
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