anti-Heat Shock 70kDa Protein 8 (HSPA8) Anticorps

HSPA8 encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. De plus, nous expédions HSPA8 Kits (32) et HSPA8 Protéines (26) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
HSPA8 3312 P11142
Anti-Rat HSPA8 HSPA8 24468 P63018
HSPA8 15481 P63017
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Top anti-HSPA8 Anticorps sur anticorps-enligne.fr

Showing 10 out of 370 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-HSPA8 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  293T cell lysate <b>Sample type:</b> rat brain lysate<br><b>Primary Dilution: </b>1:1000<br><b>Image Submitted By:</b> Jennifer Morgan, PhD &, David Busch<br>University of Texas in Austin 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Chévre Lapin Inconjugué IHC, WB WB Suggested Anti-HSPA8 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  COLO205 cell lysate <b>Sample Type:</b> 1. Lamprey CNS (20ug)<br>2. Rat Brain Lysate (20ug) <br><b>Primary Dilution: </b>1:1000<br><b>Secondary Antibody: </b>Goat anti-Rabbit HRP<br><b>Secondary Dilution:</b> 1:4000<br><b>Image Submitted by: </b>Jennifer Morgan, PhD &, David Busch<br>University of Texas in Austin 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Chèvre Inconjugué ELISA, IF, WB ABIN185659 (2µg/ml) staining of A431 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Connectez-vous pour afficher 6 to 7 Days
$358.02
Détails
Hamster Lapin Inconjugué BI, ICC, IF, IP, IHC, WB Hsc70 human Cell line mix 10ug 1 in 1000 Western Blotting. 100 μL Connectez-vous pour afficher 2 to 3 Days
$350.90
Détails
Humain Souris Inconjugué AA, Bind, ELISA, ICC, IF, IHC, IP, PLA, WB Hsc70 (1F2 H5) human cell line mix copy. 50 μg Connectez-vous pour afficher 2 to 3 Days
$220.00
Détails
Humain Lapin Inconjugué ICC, IF, IHC (p), WB WB Image Sample (50 ug of whole cell lysate) A: Mouse brain 7.5% SDS PAGE antibody diluted at 1:5000 IHC-P Image HSC70 antibody detects HSC70 protein at nucleolus on mouse prostate by immunohistochemical analysis. Sample: Paraffin-embedded mouse prostate. HSC70 antibody , dilution: 1:500. 100 μL Connectez-vous pour afficher 1 to 2 Days
$358.60
Détails
Hamster Lapin HRP BI, ICC, IF, IP, IHC, WB Immunohistochemistry analysis using Rabbit Anti-HSC70 Polyclonal Antibody . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative Solution. Primary Antibody: Rabbit Anti-HSC70 Polyclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Rabbit (green) at 1:50 for 1 hour at RT. Localization: Cytoplasm. Immunohistochemistry analysis using Rabbit Anti-HSC70 Polyclonal Antibody . Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Rabbit Anti-HSC70 Polyclonal Antibody  at 1:10000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Rabbit at 1:2000 for 1 hour at RT. Counterstain: Methyl Green at 200uL for 2 min at RT. 100 μL Connectez-vous pour afficher 2 to 3 Days
$389.40
Détails
Hamster Lapin FITC BI, ICC, IF, IP, IHC, WB Immunohistochemistry analysis using Rabbit Anti-HSC70 Polyclonal Antibody . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative Solution. Primary Antibody: Rabbit Anti-HSC70 Polyclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Rabbit (green) at 1:50 for 1 hour at RT. Localization: Cytoplasm. Immunohistochemistry analysis using Rabbit Anti-HSC70 Polyclonal Antibody . Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Rabbit Anti-HSC70 Polyclonal Antibody  at 1:10000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Rabbit at 1:2000 for 1 hour at RT. Counterstain: Methyl Green at 200uL for 2 min at RT. 100 μL Connectez-vous pour afficher 2 to 3 Days
$393.80
Détails
Hamster Lapin Alkaline Phosphatase (AP) BI, ICC, IF, IP, IHC, WB Immunohistochemistry analysis using Rabbit Anti-HSC70 Polyclonal Antibody . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative Solution. Primary Antibody: Rabbit Anti-HSC70 Polyclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Rabbit (green) at 1:50 for 1 hour at RT. Localization: Cytoplasm. Immunohistochemistry analysis using Rabbit Anti-HSC70 Polyclonal Antibody . Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Rabbit Anti-HSC70 Polyclonal Antibody  at 1:10000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Rabbit at 1:2000 for 1 hour at RT. Counterstain: Methyl Green at 200uL for 2 min at RT. 100 μL Connectez-vous pour afficher 2 to 3 Days
$396.00
Détails
Hamster Lapin Biotin BI, ICC, IF, IP, IHC, WB Immunohistochemistry analysis using Rabbit Anti-HSC70 Polyclonal Antibody . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative Solution. Primary Antibody: Rabbit Anti-HSC70 Polyclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Rabbit (green) at 1:50 for 1 hour at RT. Localization: Cytoplasm. Immunohistochemistry analysis using Rabbit Anti-HSC70 Polyclonal Antibody . Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Rabbit Anti-HSC70 Polyclonal Antibody  at 1:10000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Rabbit at 1:2000 for 1 hour at RT. Counterstain: Methyl Green at 200uL for 2 min at RT. 100 μL Connectez-vous pour afficher 2 to 3 Days
$398.20
Détails

anti-HSPA8 Anticorps mieux référencés

  1. Hamster Polyclonal HSPA8 Primary Antibody pour BI, ICC - ABIN361819 : Boorstein, Ziegelhoffer, Craig: Molecular evolution of the HSP70 multigene family. dans Journal of molecular evolution 1994 (PubMed)
    Show all 13 Pubmed References

  2. Human Monoclonal HSPA8 Primary Antibody pour AA, Bind - ABIN361800 : Bork, Sander, Valencia: An ATPase domain common to prokaryotic cell cycle proteins, sugar kinases, actin, and hsp70 heat shock proteins. dans Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)
    Show all 10 Pubmed References

  3. Human Polyclonal HSPA8 Primary Antibody pour FACS, IF - ABIN1944844 : Tsukahara, Yoshioka, Muraki: Molecular and functional characterization of HSC54, a novel variant of human heat-shock cognate protein 70. dans Molecular pharmacology 2000 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal HSPA8 Primary Antibody pour FACS, IF - ABIN650754 : Egerton, Moritz, Druker, Kelso, Simpson: Identification of the 70kD heat shock cognate protein (Hsc70) and alpha-actinin-1 as novel phosphotyrosine-containing proteins in T lymphocytes. dans Biochemical and biophysical research communications 1996 (PubMed)
    Show all 3 Pubmed References

  5. Human Polyclonal HSPA8 Primary Antibody pour IF (p), IHC (p) - ABIN709931 : Almiñana, Corbin, Tsikis, Alcântara-Neto, Labas, Reynaud, Galio, Uzbekov, Garanina, Druart, Mermillod: Oviduct extracellular vesicles protein content and their role during oviduct-embryo cross-talk. dans Reproduction (Cambridge, England) 2017 (PubMed)

  6. Fish Polyclonal HSPA8 Primary Antibody pour WB - ABIN361860 : Brown, Hong-Brown, Doxsey, Welch: Molecular chaperones and the centrosome. A role for HSP 73 in centrosomal repair following heat shock treatment. dans The Journal of biological chemistry 1996 (PubMed)
    Show all 6 Pubmed References

  7. Human Polyclonal HSPA8 Primary Antibody pour ELISA, WB - ABIN188549 : Zhang, Fan, Becker, Graff, Lee, Francomano: Comparison of gene expression profile between human chondrons and chondrocytes: a cDNA microarray study. dans Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2006 (PubMed)

  8. Human Polyclonal HSPA8 Primary Antibody pour ELISA, ICC - ABIN6262373 : Shan, Wang, Xu, Wang, Cao, Liu, Zhu: Aging as a Precipitating Factor in Chronic Restraint Stress-Induced Tau Aggregation Pathology, and the Protective Effects of Rosmarinic Acid. dans Journal of Alzheimer's disease : JAD 2016 (PubMed)

  9. Human Polyclonal HSPA8 Primary Antibody pour IHC, IHC (p) - ABIN4320595 : Yun-Hong, Chih-Fan, Chia-Wei, Yen-Chung: A study of the spatial protein organization of the postsynaptic density isolated from porcine cerebral cortex and cerebellum. dans Molecular & cellular proteomics : MCP 2011 (PubMed)

Plus d’anticorps contre HSPA8 partenaires d’interaction

Xenopus laevis Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. hsp72 (Montrer HSPA1A Anticorps) was more potent than hsc73 in generating protective immune responses against the class Ia-negative 15/0 tumors.

Human Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. Hsp70participated in PINK1 (Montrer PINK1 Anticorps)-mediated mitophagy by stabilizing PINK1 (Montrer PINK1 Anticorps).

  2. These results demonstrate not only an important mechanism of Hsc70 in facilitating EV-A71 replication, but also a target for antiviral drug development.

  3. Post-transcriptional inhibition of HSPA8 expression leads to synaptic vesicle cycling defects in multiple models of amyotrophic lateral sclerosis.

  4. Taken together, these data suggest hat (Montrer MGEA5 Anticorps) the altered hydrogen bonding observed in the Hsc70 C17W mutant (where the connectivity between Mg2 (Montrer MUC7 Anticorps)+.nucleotide and E175 is also disrupted) could bring about changes to Hsc70 domain communication, affecting peptide association while also limiting ATP hydrolysis.

  5. The roles of the E3 ubiquitin ligase (Montrer MUL1 Anticorps), carboxy-terminus Hsc70 interacting protein (Montrer ST13 Anticorps) (CHIP) in various types of cancers.

  6. Hsc70/Hsp90 (Montrer HSP90 Anticorps) chaperones contribute to the conformational and functional maintenance of DeltaF508-CFTR (Montrer CFTR Anticorps) at 37 degrees C.

  7. Engagement of the oligomer by LAP1 (Montrer ANPEP Anticorps) triggers ATP hydrolysis and rapid complex disassembly. Thus the Torsin complex is a highly dynamic assembly whose oligomeric state is tightly controlled by distinctively localized cellular cofactors.

  8. Downregulation of Hsc70, Hsp70 (Montrer HSP70 Anticorps), and IL-15 (Montrer IL15 Anticorps) expression at gene and/or protein levels might support the retention of fertilization products in cases of missed abortion and blighted ovum.

  9. STRO-1 binds to immune-precipitated HSC70 and siRNA-mediated knock down of HSPA8 reduced STRO-1 binding.

  10. Synapsin is part of a multiprotein complex enriched in chaperones/cochaperones including Hsc70. Hsc70 chaperone activity is required for the cytosolic slow axonal transport of synapsin.

Cow (Bovine) Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. Single-particle fluorescence imaging tracks the dynamics of Hsc70 and its clathrin substrate in real time.

  2. The interaction of the molecular chaperone (Montrer HSP90AA1 Anticorps) Hsc70 (HSPA8) with recombinant PrP (Montrer PRNP Anticorps) was investigated.

  3. Structure of clathrin coat with bound Hsc70 and auxilin (Montrer DNAJC6 Anticorps).

  4. specific association between HSP73 and gentamicin may reduce the chaperone activity of HSP73 in vitro and/or in vivo

  5. report role of HSC70 in the regulation of NMT

  6. studied the process of disassembly by using cryo-electron microscopy to identify the initial binding site of Hsc70 on clathrin-C58J baskets at pH 6, under which conditions disassembly does not proceed further. Hsc70 interactions involve two sites

  7. Coats assembled from recombinant clathrin are good substrates for ATP- and auxilin (Montrer DNAJC6 Anticorps)-dependent, Hsc70-catalyzed uncoating.

  8. The structure of an Hsp110 (Montrer HSPH1 Anticorps):Hsc70 nucleotide exchange complex, is reported.

  9. analysis of the formation of a stable complex between chaperonin-containing TCP-1 (Montrer CCT6A Anticorps) (CCT (Montrer TCP1 Anticorps)) and Hsc70

  10. Elevated expression of bovine heat shock cognate (hsc)70 protein increases diabetes and inflammation following islet beta cell damage in a transgenic mouse model.

Mouse (Murine) Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. Post-transcriptional inhibition of HSPA8 expression leads to synaptic vesicle cycling defects in multiple models of amyotrophic lateral sclerosis.

  2. Synapsin is part of a multiprotein complex enriched in chaperones/cochaperones including Hsc70. Hsc70 chaperone activity is required for the cytosolic slow axonal transport of synapsin.

  3. Hsc70 interacts with FILIP (Montrer FILIP1 Anticorps) to mediate its effects on non-muscle myosin IIb (Montrer MYH10 Anticorps) and to regulate spine morphology

  4. HSPA1A (Montrer HSPA1A Anticorps) and HSPA8 have roles in parturition through stimulating immune inflammatory and estrogen response

  5. intracellular Salmonella recruit the host proteins LAMP-2A and Hsc73, key components of the host protein turnover pathway known as chaperone-mediated autophagy involved in transport of cytosolic proteins to the lysosome for degradation.

  6. these data demonstrate a novel interaction between Hsc70 and TH that regulates the activity and localization of the enzyme to synaptic vesicles, suggesting an important role for Hsc70 in dopamine homeostasis.

  7. C terminus of the hsc-70 LID domain as the structural interface interacting with endosomal Phosphatidylserine

  8. the association of MNSFbeta (Montrer FAU Anticorps) with HSPA8 may promote RANKL (Montrer TNFSF11 Anticorps)-induced osteoclastogenesis.

  9. Hspa8 plays a vital role in genetic differences in responses to stress and ethanol and their interactions

  10. PTEN-like domains of GAK and auxilin are not essential for Hsc70-dependent chaperoning and uncoating of clathrin, but depending on the tissue, these domains appear to increase the efficiency of these co-chaperones.

HSPA8 profil antigène

Profil protéine

This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with HSPA8

  • heat shock protein family A (Hsp70) member 8 L homeolog (hspa8.L) anticorps
  • heat shock protein family A (Hsp70) member 8 (HSPA8) anticorps
  • heat shock protein family A (Hsp70) member 8 (Hspa8) anticorps
  • heat shock 70kDa protein 8 (HSPA8) anticorps
  • heat shock protein 8 (Hspa8) anticorps
  • heat shock protein 8 (hspa8) anticorps
  • 2410008N15Rik anticorps
  • HSC54 anticorps
  • Hsc70 anticorps
  • Hsc71 anticorps
  • Hsc73 anticorps
  • HSP71 anticorps
  • Hsp73 anticorps
  • Hspa10 anticorps
  • LAP1 anticorps
  • NIP71 anticorps
  • wu:fb01g06 anticorps
  • wu:fi48b06 anticorps

Protein level used designations for HSPA8

LPS-associated protein 1 , N-myristoyltransferase inhibitor protein 71 , constitutive heat shock protein 70 , heat shock 70kd protein 10 , heat shock cognate 71 kDa protein , heat shock cognate protein 54 , lipopolysaccharide-associated protein 1 , Hsc70 ATPase , heat shock 70 kDa protein 8 , heat shock 70kd protein 10 (HSC71) , heat shock cognate 71 kD protein , Heat shock cognate protein 70 , heat shock 70kD protein 8 , heat shock protein 8 , heat shock protein A8 , heat shock cognate 70 , heat shock cognate 71 kDa protein-like protein , heat shock protein 70 cognate , heat shock cognate hsc73 , heat shock protein cognate 70 , heat shock 70kDa protein 8 , heat shock cognate 71-kd protein

GENE ID SPECIES
379319 Xenopus laevis
3312 Homo sapiens
281831 Bos taurus
24468 Rattus norvegicus
395853 Gallus gallus
479406 Canis lupus familiaris
100009679 Equus caballus
100172711 Pongo abelii
15481 Mus musculus
573376 Danio rerio
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