anti-Heat Shock 70kDa Protein 8 (HSPA8) Anticorps

HSPA8 encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. De plus, nous expédions HSPA8 Kits (32) et HSPA8 Protéines (26) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
HSPA8 3312 P11142
Anti-Rat HSPA8 HSPA8 24468 P63018
HSPA8 15481 P63017
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Top anti-HSPA8 Anticorps sur anticorps-enligne.fr

Showing 10 out of 376 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué ICC, IHC (fro), IHC (p), WB Anti-Hsc70 antibody, ICC ICC: HELA Cell Anti-Hsc70 antibody, IHC(F) IHC(F): Rat Intestine Tissue 100 μg Connectez-vous pour afficher 4 to 6 Days
$280.00
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-HSPA8 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  293T cell lysate Sample type: rat brain lysatePrimary Dilution: 1:1000Image Submitted By: Jennifer Morgan, PhD &, David BuschUniversity of Texas in Austin 100 μL Connectez-vous pour afficher 2 to 3 Days
$319.00
Détails
Chévre Lapin Inconjugué IHC, WB WB Suggested Anti-HSPA8 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  COLO205 cell lysate Sample Type: 1. Lamprey CNS (20ug)2. Rat Brain Lysate (20ug) Primary Dilution: 1:1000Secondary Antibody: Goat anti-Rabbit HRPSecondary Dilution: 1:4000Image Submitted by: Jennifer Morgan, PhD &, David BuschUniversity of Texas in Austin 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Chèvre Inconjugué ELISA, IF, WB ABIN185659 (2µg/ml) staining of A431 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN185659 (0.03µg/ml) staining of HepG2 (A) and NIH3T3 (B) cell lysate (35µg protein in RIPA buffer). Detected by chemiluminescence. 100 μg Connectez-vous pour afficher 6 to 7 Days
$429.84
Détails
Hamster Lapin Inconjugué BI, ICC, IF, IP, IHC, WB Hsc70 human Cell line mix 10ug 1 in 1000 Western Blotting. 100 μL Connectez-vous pour afficher 3 to 4 Days
$414.70
Détails
Humain Souris Inconjugué AA, Bind, ELISA, ICC, IF, IHC, IP, PLA, WB Hsc70 (1F2 H5) human cell line mix copy. 50 μg Connectez-vous pour afficher 3 to 4 Days
$260.00
Détails
Hamster Lapin FITC BI, ICC, IF, IP, IHC, WB Immunohistochemistry analysis using Rabbit Anti-HSC70 Polyclonal Antibody . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative Solution. Primary Antibody: Rabbit Anti-HSC70 Polyclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Rabbit (green) at 1:50 for 1 hour at RT. Localization: Cytoplasm. Immunohistochemistry analysis using Rabbit Anti-HSC70 Polyclonal Antibody . Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Rabbit Anti-HSC70 Polyclonal Antibody  at 1:10000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Rabbit at 1:2000 for 1 hour at RT. Counterstain: Methyl Green at 200uL for 2 min at RT. 100 μL Connectez-vous pour afficher 3 to 4 Days
$465.40
Détails
Hamster Lapin PerCP BI, ICC, IF, IP, IHC, WB Immunohistochemistry analysis using Rabbit Anti-HSC70 Polyclonal Antibody . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative Solution. Primary Antibody: Rabbit Anti-HSC70 Polyclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Rabbit (green) at 1:50 for 1 hour at RT. Localization: Cytoplasm. Immunohistochemistry analysis using Rabbit Anti-HSC70 Polyclonal Antibody . Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Rabbit Anti-HSC70 Polyclonal Antibody  at 1:10000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Rabbit at 1:2000 for 1 hour at RT. Counterstain: Methyl Green at 200uL for 2 min at RT. 100 μL Connectez-vous pour afficher 3 to 4 Days
$474.50
Détails
Hamster Lapin APC BI, ICC, IF, IP, IHC, WB Immunohistochemistry analysis using Rabbit Anti-HSC70 Polyclonal Antibody . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative Solution. Primary Antibody: Rabbit Anti-HSC70 Polyclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Rabbit (green) at 1:50 for 1 hour at RT. Localization: Cytoplasm. Immunohistochemistry analysis using Rabbit Anti-HSC70 Polyclonal Antibody . Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Rabbit Anti-HSC70 Polyclonal Antibody  at 1:10000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Rabbit at 1:2000 for 1 hour at RT. Counterstain: Methyl Green at 200uL for 2 min at RT. 100 μL Connectez-vous pour afficher 3 to 4 Days
$474.50
Détails
Hamster Lapin Atto 700 BI, ICC, IF, IP, IHC, WB Immunohistochemistry analysis using Rabbit Anti-HSC70 Polyclonal Antibody . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative Solution. Primary Antibody: Rabbit Anti-HSC70 Polyclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Rabbit (green) at 1:50 for 1 hour at RT. Localization: Cytoplasm. Immunohistochemistry analysis using Rabbit Anti-HSC70 Polyclonal Antibody . Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Rabbit Anti-HSC70 Polyclonal Antibody  at 1:10000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Rabbit at 1:2000 for 1 hour at RT. Counterstain: Methyl Green at 200uL for 2 min at RT. 100 μL Connectez-vous pour afficher 3 to 4 Days
$475.80
Détails

anti-HSPA8 Anticorps mieux référencés

  1. Hamster Polyclonal HSPA8 Primary Antibody pour BI, ICC - ABIN361819 : Boorstein, Ziegelhoffer, Craig: Molecular evolution of the HSP70 multigene family. dans Journal of molecular evolution 1994 (PubMed)
    Show all 13 Pubmed References

  2. Human Polyclonal HSPA8 Primary Antibody pour ICC, IHC (fro) - ABIN3044300 : Wu, Cao, Gao, Chen, Wang, Zumbika, Qian: Down-modulation of heat shock protein 70 and up-modulation of Caspase-3 during schisandrin B-induced apoptosis in human hepatoma SMMC-7721 cells. dans World journal of gastroenterology 2004 (PubMed)
    Show all 5 Pubmed References

  3. Human Monoclonal HSPA8 Primary Antibody pour AA, Bind - ABIN361800 : Bork, Sander, Valencia: An ATPase domain common to prokaryotic cell cycle proteins, sugar kinases, actin, and hsp70 heat shock proteins. dans Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)
    Show all 10 Pubmed References

  4. Human Polyclonal HSPA8 Primary Antibody pour FACS, IF - ABIN650754 : Egerton, Moritz, Druker, Kelso, Simpson: Identification of the 70kD heat shock cognate protein (Hsc70) and alpha-actinin-1 as novel phosphotyrosine-containing proteins in T lymphocytes. dans Biochemical and biophysical research communications 1996 (PubMed)
    Show all 3 Pubmed References

  5. Human Polyclonal HSPA8 Primary Antibody pour FACS, IF - ABIN1944844 : Tsukahara, Yoshioka, Muraki: Molecular and functional characterization of HSC54, a novel variant of human heat-shock cognate protein 70. dans Molecular pharmacology 2000 (PubMed)
    Show all 2 Pubmed References

  6. Human Polyclonal HSPA8 Primary Antibody pour ELISA, WB - ABIN188549 : Zhang, Fan, Becker, Graff, Lee, Francomano: Comparison of gene expression profile between human chondrons and chondrocytes: a cDNA microarray study. dans Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2006 (PubMed)
    Show all 2 Pubmed References

  7. Human Polyclonal HSPA8 Primary Antibody pour IF (p), IHC (p) - ABIN709931 : Almiñana, Corbin, Tsikis, Alcântara-Neto, Labas, Reynaud, Galio, Uzbekov, Garanina, Druart, Mermillod: Oviduct extracellular vesicles protein content and their role during oviduct-embryo cross-talk. dans Reproduction (Cambridge, England) 2017 (PubMed)

  8. Cow (Bovine) Polyclonal HSPA8 Primary Antibody pour IHC (fro), WB - ABIN549306 : Sugita, Kongo, Shiba: Molecular dissection of the butyrate action revealed the involvement of mitogen-activated protein kinase in cystic fibrosis transmembrane conductance regulator biogenesis. dans Molecular pharmacology 2004 (PubMed)

  9. Fish Polyclonal HSPA8 Primary Antibody pour WB - ABIN361860 : Brown, Hong-Brown, Doxsey, Welch: Molecular chaperones and the centrosome. A role for HSP 73 in centrosomal repair following heat shock treatment. dans The Journal of biological chemistry 1996 (PubMed)
    Show all 6 Pubmed References

Plus d’anticorps contre HSPA8 partenaires d’interaction

Xenopus laevis Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. hsp72 was more potent than hsc73 in generating protective immune responses against the class Ia-negative 15/0 tumors.

Human Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. Data suggest that both the small heat shock protein HspB1/Hsp27 and the constitutive chaperone Hsc70/HspA8 interact with tau to prevent tau-fibril/amyloid formation. Hsc70 is highly efficient at preventing tau-fibril elongation, possibly by capping ends of tau-fibrils. (HspB1 = heat shock protein family B small member 1; Hsc70 = heat shock protein family A Hsp70)

  2. This study demonstrated that particular distribution for HSC70 and PSMC4 in the cytoplasm and accumulation within Lewy body in the dopaminergic neurons of the substantia nigra in Parkinson patients.

  3. Hsp70participated in PINK1-mediated mitophagy by stabilizing PINK1.

  4. These results demonstrate not only an important mechanism of Hsc70 in facilitating EV-A71 replication, but also a target for antiviral drug development.

  5. Post-transcriptional inhibition of HSPA8 expression leads to synaptic vesicle cycling defects in multiple models of amyotrophic lateral sclerosis.

  6. Taken together, these data suggest hat the altered hydrogen bonding observed in the Hsc70 C17W mutant (where the connectivity between Mg2+.nucleotide and E175 is also disrupted) could bring about changes to Hsc70 domain communication, affecting peptide association while also limiting ATP hydrolysis.

  7. The roles of the E3 ubiquitin ligase, carboxy-terminus Hsc70 interacting protein (CHIP) in various types of cancers.

  8. Hsc70/Hsp90 chaperones contribute to the conformational and functional maintenance of DeltaF508-CFTR at 37 degrees C.

  9. Engagement of the oligomer by LAP1 triggers ATP hydrolysis and rapid complex disassembly. Thus the Torsin complex is a highly dynamic assembly whose oligomeric state is tightly controlled by distinctively localized cellular cofactors.

  10. Downregulation of Hsc70, Hsp70, and IL-15 expression at gene and/or protein levels might support the retention of fertilization products in cases of missed abortion and blighted ovum.

  11. STRO-1 binds to immune-precipitated HSC70 and siRNA-mediated knock down of HSPA8 reduced STRO-1 binding.

  12. Synapsin is part of a multiprotein complex enriched in chaperones/cochaperones including Hsc70. Hsc70 chaperone activity is required for the cytosolic slow axonal transport of synapsin.

  13. study demonstrates a critical role of Hsc70 in SV40 endoplasmic reticulum-to-cytosol penetration and reveal how SGTA controls Hsc70 to impact this process

  14. In fact, DnaJC5 overexpression induced tau release in cells, neurons, and brain tissue, but only when activity of the chaperone Hsc70 was intact and when tau was able to associate with this chaperone.

  15. HSPA1A and HSPA8 have roles in parturition through stimulating immune inflammatory and estrogen response

  16. These results suggest that Bag1 and Bag3 control the stability of the Hsc70-client complex using at least two distinct protein-protein contacts, providing a previously under-appreciated layer of molecular regulation in the human Hsc70 system.

  17. While cerebrospinal fluid Nrf2 and HSPA8 do not appear to offer diagnostic biomarkers for Parkinson's disease (PD), the associations between Nrf2 levels and UPDRS scores in LRRK2 + PD patients merit further investigation

  18. HSPA8 maintains pluripotency of human pluripotent stem cells by binding to the master pluripotency regulator OCT4 and facilitating its DNA-binding activity.

  19. heat shock cognate 70 (HSC70) is an essential component of Aes foci in colorectal cancer cells.

  20. Cx43-Hsc70 interaction regulates cell cycle G1/S progression through a novel mechanism by which Cx43-Hsc70 interaction prevents the nuclear accumulation of p27 through controlling the nuclear translocation of cyclin D1-CDK4-p27 complex.

Cow (Bovine) Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. Single-particle fluorescence imaging tracks the dynamics of Hsc70 and its clathrin substrate in real time.

  2. The interaction of the molecular chaperone Hsc70 (HSPA8) with recombinant PrP was investigated.

  3. Structure of clathrin coat with bound Hsc70 and auxilin.

  4. specific association between HSP73 and gentamicin may reduce the chaperone activity of HSP73 in vitro and/or in vivo

  5. report role of HSC70 in the regulation of NMT

  6. studied the process of disassembly by using cryo-electron microscopy to identify the initial binding site of Hsc70 on clathrin-C58J baskets at pH 6, under which conditions disassembly does not proceed further. Hsc70 interactions involve two sites

  7. Coats assembled from recombinant clathrin are good substrates for ATP- and auxilin-dependent, Hsc70-catalyzed uncoating.

  8. The structure of an Hsp110:Hsc70 nucleotide exchange complex, is reported.

  9. analysis of the formation of a stable complex between chaperonin-containing TCP-1 (CCT) and Hsc70

  10. Elevated expression of bovine heat shock cognate (hsc)70 protein increases diabetes and inflammation following islet beta cell damage in a transgenic mouse model.

Mouse (Murine) Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. Post-transcriptional inhibition of HSPA8 expression leads to synaptic vesicle cycling defects in multiple models of amyotrophic lateral sclerosis.

  2. Synapsin is part of a multiprotein complex enriched in chaperones/cochaperones including Hsc70. Hsc70 chaperone activity is required for the cytosolic slow axonal transport of synapsin.

  3. Hsc70 interacts with FILIP to mediate its effects on non-muscle myosin IIb and to regulate spine morphology

  4. HSPA1A and HSPA8 have roles in parturition through stimulating immune inflammatory and estrogen response

  5. intracellular Salmonella recruit the host proteins LAMP-2A and Hsc73, key components of the host protein turnover pathway known as chaperone-mediated autophagy involved in transport of cytosolic proteins to the lysosome for degradation.

  6. these data demonstrate a novel interaction between Hsc70 and TH that regulates the activity and localization of the enzyme to synaptic vesicles, suggesting an important role for Hsc70 in dopamine homeostasis.

  7. C terminus of the hsc-70 LID domain as the structural interface interacting with endosomal Phosphatidylserine

  8. the association of MNSFbeta with HSPA8 may promote RANKL-induced osteoclastogenesis.

  9. Hspa8 plays a vital role in genetic differences in responses to stress and ethanol and their interactions

  10. PTEN-like domains of GAK and auxilin are not essential for Hsc70-dependent chaperoning and uncoating of clathrin, but depending on the tissue, these domains appear to increase the efficiency of these co-chaperones.

  11. mass spectrometry-based proteomic analysis identified heat shock cognate 70 (HSC70) as a novel binding protein of FSP27

  12. These findings indicate that wild type ILK and the non-oncogenic ILK(R211A) mutation comprise a cardioprotective module with Hsp/c70.

  13. these data provide evidence for Hsc70 as a novel neuronal interactor of NF-kappaB p65.

  14. In heat stress conditions, Hsp73 is mobilized to prevent apoptosis in the testes and epididymis, and assists Hsp72 in the repair of stress-altered protein conformations.

  15. 70-kDa heat shock cognate protein hsc70 mediates calmodulin-dependent nuclear import of the sex-determining factor SRY.

  16. Hsc70, Hdj1 and Hdj2 interact with soluble and fibrillar alpha-synuclein

  17. BAG3 and Hsc70 interact with actin capping protein CapZ to maintain myofibrillar integrity under mechanical stress.

  18. In this study, we report an identification of Hsc70 (Heat shock cognate protein 70) as a critical mediator of RGS9-2 expression that is specifically recruited to the intrinsically disordered C-terminal domain of RGS9-2 following dissociation from R7BP.

  19. data demonstrate for the first time that HSP70 overexpression with adenovirus injection prevented the lipopolysaccharide-induced increase in tumor necrosis factor-alpha and IL-6 levels in rats.

  20. Heat shock protein 70 (Hsc70) plays a significant role in vascular endothelial cells via the phosphatidylinositol 3-kinase/Akt pathway.

HSPA8 profil antigène

Profil protéine

This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with HSPA8

  • heat shock protein family A (Hsp70) member 8 L homeolog (hspa8.L) anticorps
  • heat shock protein family A (Hsp70) member 8 (HSPA8) anticorps
  • heat shock protein family A (Hsp70) member 8 (Hspa8) anticorps
  • heat shock 70kDa protein 8 (HSPA8) anticorps
  • heat shock protein 8 (Hspa8) anticorps
  • heat shock protein 8 (hspa8) anticorps
  • 2410008N15Rik anticorps
  • HSC54 anticorps
  • Hsc70 anticorps
  • Hsc71 anticorps
  • Hsc73 anticorps
  • HSP71 anticorps
  • Hsp73 anticorps
  • Hspa10 anticorps
  • LAP1 anticorps
  • NIP71 anticorps
  • wu:fb01g06 anticorps
  • wu:fi48b06 anticorps

Protein level used designations for HSPA8

LPS-associated protein 1 , N-myristoyltransferase inhibitor protein 71 , constitutive heat shock protein 70 , heat shock 70kd protein 10 , heat shock cognate 71 kDa protein , heat shock cognate protein 54 , lipopolysaccharide-associated protein 1 , Hsc70 ATPase , heat shock 70 kDa protein 8 , heat shock 70kd protein 10 (HSC71) , heat shock cognate 71 kD protein , Heat shock cognate protein 70 , heat shock 70kD protein 8 , heat shock protein 8 , heat shock protein A8 , heat shock cognate 70 , heat shock cognate 71 kDa protein-like protein , heat shock protein 70 cognate , heat shock cognate hsc73 , heat shock protein cognate 70 , heat shock 70kDa protein 8 , heat shock cognate 71-kd protein

GENE ID SPECIES
379319 Xenopus laevis
3312 Homo sapiens
281831 Bos taurus
24468 Rattus norvegicus
395853 Gallus gallus
479406 Canis lupus familiaris
100009679 Equus caballus
100172711 Pongo abelii
15481 Mus musculus
573376 Danio rerio
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