anti-Kinesin Family Member 4A (KIF4A) Anticorps

KIF4A encodes a member of the kinesin 4 subfamily of kinesin related proteins. De plus, nous expédions et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
KIF4A 24137 O95239
KIF4A 84393  
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Showing 10 out of 62 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Lapin Inconjugué IC, IF, WB Immunofluorescent analysis of KIF4A staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of KIF4A expression in MCF7 (A), SP2/0 (B) whole cell lysates. 200 μL 13 to 14 Days
Humain Chèvre Inconjugué ELISA, FACS, IF, WB ABIN184768 (2µg/ml) staining of nuclear NIH3T3 (A) and (2ug/ml) negative control Human Ovary (B) lysate. (35µg protein in RIPA buffer) Detected by chemiluminescence. ABIN184768 Immunofluorescence analysis of paraformaldehyde fixed U2OS cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (4ug/ml), showing nuclear staining. The nuclear stain is DAPI (blue) 100 μg 6 to 7 Days
Humain Lapin Inconjugué ELISA, WB Western blot analysis of extracts from HeLa cells, using KIF4A Antibody. The lane on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
Humain Lapin Inconjugué WB WB Image Sample (30 ug of whole cell lysate) A: H1299 5% SDS PAGE antibody diluted at 1:1000 100 μL 3 to 4 Days
Humain Lapin Inconjugué ELISA, WB 100 μL Disponible
Humain Lapin Inconjugué ELISA, ICC, IF, WB ABIN6275012 staining  HeLa cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibod 100 μL 11 to 12 Days
Humain Lapin Inconjugué WB Western blot analysis of extracts of various cells, using KIF4A antibody. Western blot analysis of extracts of various cell lines, using KIF4A antibody (ABIN4904155) at 1:7000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s. 100 μL 11 to 13 Days
Boeuf (Vache) Chèvre Inconjugué IF, WB   0.1 mg 6 to 8 Days
Boeuf (Vache) Chèvre Inconjugué ELISA   100 μg 11 to 14 Days
Humain Lapin Inconjugué ELISA, WB   100 μg 2 to 3 Days

anti-Kinesin Family Member 4A Anticorps mieux référencés

  1. Human Polyclonal KIF4A Primary Antibody pour ICC, IF - ABIN249557 : Sekine, Okada, Noda, Kondo, Aizawa, Takemura, Hirokawa: A novel microtubule-based motor protein (KIF4) for organelle transports, whose expression is regulated developmentally. dans The Journal of cell biology 1994 (PubMed)

  2. Human Polyclonal KIF4A Primary Antibody pour IP, WB - ABIN5665648 : Shrestha, Wilmeth, Eyer, Shuster: PRC1 controls spindle polarization and recruitment of cytokinetic factors during monopolar cytokinesis. dans Molecular biology of the cell 2012 (PubMed)

Plus d’anticorps contre Kinesin Family Member 4A partenaires d’interaction

Human Kinesin Family Member 4A (KIF4A) interaction partners

  1. Phosphorylated Kif4A (Kif4AWT) or Cdk phospho-mimetic Kif4A mutant (Kif4ATE) associated with chromosomes and condensin I (non-SMC subunit CAP-G and core subunit SMC2) to regulate chromosome condensation, spindle morphology, and chromosome congression/alignment in early mitosis.

  2. AMPK and Aurora B competitively phosphoregulate KIF4A during mitotic phase due to overlapping recognition motifs, resulting in the elaborate phosphoregulation for KIF4A-dependent central spindle length control.

  3. We found that KIF4A was dominantly regulated by FOXM1c among the four isoforms, and further identified KIF4A as a direct downstream target of FOXM1c. Inhibiting FOXM1 decreased KIF4A expression in hepatocellular carcinoma (HCC) cells, whereas its overexpression had the opposite effect.

  4. KIF4A may act as a prognostic biomarker and potential therapeutic target in human Hepatocellular carcinoma.

  5. The results revealed that circKIF4A and KIF4A could bind to miR-375 and that circKIF4A regulated the expression of KIF4A via sponging miR-375.

  6. our novel results revealed that Cdk1-dependent KIF4A phosphorylation at S1186 is a trigger for chromosomal organization during early mitosis.

  7. Here, the authors show that the collective activity of PRC1 and Kif4A results in relative microtubule sliding and concurrent end-tag formation on antiparallel microtubules.

  8. This work identified KIF4A as a potential predictive and prognostic marker for hepatocellular carcinoma.

  9. KIF4A promotes drug resistance of lung adenocarcinoma cells through transporting LRP-based vaults along microtubules towards the cell membrane

  10. High KIF4A expression is associated with lung cancer.

  11. decrease in Aurora B results in diminished binding of the chromokinesin Kif4A to chromosome arms.

  12. Neither KIF4A nor condensin I alone can sufficiently accumulate on the chromosomal axis and confer physiological properties to chromosomes, thus establishing that the functions of KIF4A and condensin I are inseparable

  13. Chromokinesin represents a kinesin superfamily regulating cell division through chromosome and spindle. (Review)

  14. Hepatitis B virus activates the KIF4A gene promoter and upregulates the mRNA and protein expression of KIF4A.

  15. KIF4A and PP2A-B56G and -B56E create a spatially restricted negative feedback loop counteracting Aurora B in anaphase.

  16. KIF4A might be a key regulator for tumoral progression in OSCCs.

  17. Genetic association of KIF4A and KIF5C mutations in intellectual disability and synaptic function.

  18. The KIF4A phosphorylation by Aurora B stimulates the maximal microtubule-dependent ATPase activity of KIF4A and promotes its interaction with PRC1.

  19. Studies reveal how interactions between the conserved nonmotor MAP, PRC1, and the motor protein, kinesin-4, generate filament length-dependent tags at microtubule plus ends. PRC1 tags ends of microtubules in dividing cells and the size of these tags increases linearly with filament length.

  20. Abeta impairs the assembly and maintenance of the mitotic spindle. Mechanistically, these defects result from Abeta's inhibition of mitotic motor kinesins, including Eg5, KIF4A and MCAK.

Kinesin Family Member 4A (KIF4A) profil antigène

Profil protéine

This gene encodes a member of the kinesin 4 subfamily of kinesin related proteins. The encoded protein is an ATP dependent microtubule-based motor protein that is involved in the intracellular transport of membranous organelles. This protein also associates with condensed chromosome arms and may be involved in maintaining chromosome integrity during mitosis. This protein may also be involved in the organization of the central spindle prior to cytokinesis. A pseudogene of this gene is found on chromosome X.

Gene names and symbols associated with KIF4A

  • kinesin family member 4A (kif4a) anticorps
  • kinesin family member 4A (KIF4A) anticorps
  • chromosome-associated kinesin KIF4A (LOC100412591) anticorps
  • kinesin family member 4A (Kif4a) anticorps
  • Kif4 anticorps
  • KIF4A anticorps
  • KIF4G1 anticorps
  • MGC89367 anticorps

Protein level used designations for KIF4A

kinesin family member 4A , chromosome-associated kinesin KIF4A-like , chromokinesin-A , chromosome-associated kinesin KIF4A , kinesin family member 4 , kinesin heavy chain member 4 , chromokinesin , chromosome-associated kinesin KIF4

448410 Xenopus (Silurana) tropicalis
100055648 Equus caballus
100220719 Taeniopygia guttata
100412591 Callithrix jacchus
100449140 Pongo abelii
100477054 Ailuropoda melanoleuca
100600625 Nomascus leucogenys
24137 Homo sapiens
100152604 Sus scrofa
537127 Bos taurus
84393 Rattus norvegicus
395823 Gallus gallus
491941 Canis lupus familiaris
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