anti-Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1) Anticorps

May play a role in regulating axonal regeneration and plasticity in the adult central nervous system (By similarity). De plus, nous expédions LINGO1 Protéines (6) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
LINGO1 84894 Q96FE5
LINGO1 235402 Q9D1T0
LINGO1 315691  
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Top anti-LINGO1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 120 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, IHC (p) Anti-LINGO1 antibody  ABIN1049009 IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11 to 14 Days
$484.00
Détails
Poulet Lapin Inconjugué IHC, IHC (p) Anti-LINGO1 antibody  ABIN1049010 IHC staining of human brain, hippocampus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-LINGO1 antibody IHC of human brain, hippocampus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11 to 14 Days
$484.00
Détails
Humain Lapin Inconjugué WB 100 μL 11 to 14 Days
$537.17
Détails
Roussette (Chauve-souris) Lapin Inconjugué IHC, IHC (p) Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with LINGO1 antibody ABIN239799 at 20 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-LINGO1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11 to 14 Days
$484.00
Détails
Humain Lapin Inconjugué IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti-Lingo-1 Polyclonal Antibody, Unconjugated (ABIN738801) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and rat brain tissue labeled with Anti-Lingo-1 Polyclonal Antibody, unconjugated  (ABIN738801)  at 1: 200 followed by incubation with conjugated secondary antibody and DAB staining 100 μL 3 to 7 Days
$317.90
Détails
Humain Lapin Inconjugué WB Western blot analysis of LINGO1 Antibody in mouse cerebellum tissue lysates (35ug/lane) 400 μL 2 to 3 Days
$515.63
Détails
Humain Lapin Inconjugué IHC (p), WB Western blot analysis of LINGO1 using rabbit polyclonal LINGO1 Antibody.293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the LINGO1 gene (Lane 2). Formalin-fixed and paraffin-embedded human brain tissue reacted with LINGO1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL 2 to 3 Days
$515.63
Détails
Humain Lapin Inconjugué WB Western blot analysis of extract of various cells, using LINGO1 antibody. 100 μL 11 to 13 Days
$366.77
Détails
Humain Lapin Inconjugué IHC (p) 50 μg 12 to 14 Days
$686.14
Détails
Humain Lapin Inconjugué IHC (p) 50 μg 12 to 14 Days
$686.14
Détails

anti-LINGO1 Anticorps mieux référencés

  1. Human Polyclonal LINGO1 Primary Antibody pour IHC (p), ELISA - ABIN543819 : Satoh, Tabunoki, Yamamura, Arima, Konno: TROY and LINGO-1 expression in astrocytes and macrophages/microglia in multiple sclerosis lesions. dans Neuropathology and applied neurobiology 2007 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal LINGO1 Primary Antibody pour CyTOF, FACS - ABIN4900323 : Meabon, De Laat, Ieguchi, Wiley, Hudson, Bothwell: LINGO-1 protein interacts with the p75 neurotrophin receptor in intracellular membrane compartments. dans The Journal of biological chemistry 2015 (PubMed)

Plus d’anticorps contre LINGO1 partenaires d’interaction

Human Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1) interaction partners

  1. LINGO1 might be a positive primary glioblastoma prognostic gene and C7orf31 and VEGFA might be negative prognosticators.

  2. We identified homozygous missense variants in LINGO1, p.(Arg290His) in family F162 and p.(Tyr288Cys) in family PKMR65. Both variants were predicted to be pathogenic, and segregated with the phenotype in the respective families. Molecular modeling of LINGO1 suggests that both variants interfere with the glycosylation of the protein.

  3. LINGO1 rs11856808 plays a protective role by decreasing the risk for PD, but not for MSA, in Chinese population.

  4. LINGO1 protein acts as a gateway protein internalizing into the tumor cells when engaged by antibody and can carry antibody conjugated with drugs to kill Ewing sarcoma cells.

  5. Data indicate that leucine-rich repeat neuronal protein 1 (LINGO-1) is intracellular and competes with Nogo-66 receptor (NgR) for binding to p75 neurotrophin receptor (p75NTR).

  6. The results of this study show Increased LINGO1 in the cerebellum of essential tremor patients.

  7. Lingo-1 signaling is altered in the schizophrenia brain.

  8. LINGO-1 can directly bind to ErbB2, block ErbB2 translocation into lipid rafts, and inhibit its phosphorylation.

  9. This review found that several gene variants in the LINGO1 gene may increase the risk of essential tremor.

  10. LINGO1 variants are associated with essential tremor in Chinese Han female patients.

  11. This study demonistrated that theLINGO1 rs9652490 and rs11856808 polymorphisms are not associated with risk for multiple sclerosis.

  12. LINGO-1 potentiates neuronal apoptosis, likely by inhibiting WNK3 kinase activity.

  13. Results of a meta-analysis suggest a relationship between LINGO1 rs11856808 polymorphism and risk of essential tremor (ET) and familial ET, while rs9652490 polymorphism is only associated with the risk for familial ET.

  14. the N-terminal region containing the leucine-rich repeats along with the transmembrane and cytoplasmic domains of LINGO-1 are not required for self-interaction or interaction with amyloid precursor protein

  15. the present meta-analysis does not support the notion that LINGO1 rs9652490 SNP is a major genetic risk factor for parkinson disease.[meta-analysis]

  16. This study showed that LINGO1 rs9652490 and rs11856808 are not associated with the risk of Parkinson's disease.

  17. LINGO-1, a transmembrane signaling protein, inhibits oligodendrocyte differentiation and myelination through intercellular self-interactions

  18. There were no significant differences in frequencies for all alleles between the essential tremor (ET) group and controls; however, an association of genotype A/G of the SNP rs9652490 with the familial ET phenotype was found.

  19. Single nucleotide polymorphism(SNP)s of LINGO1 play a role in the development of Parkinson's disease in the Italian population.

  20. LINGO1 variants are not a major risk factor for developing familial essential tremor in this population, which suggests the existence of other genetic risk factors responsible for familial essential tremor in this movement disorder clinic population.

Mouse (Murine) Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1) interaction partners

  1. Myelin loss and subsequent axon degeneration contributes to a variety of neurological diseases, such as multiple sclerosis (MS).

  2. These data provide morphometric and functional evidence of enhancement of remyelination associated with antagonism of LINGO-1

  3. LINGO-1, a transmembrane signaling protein, inhibits oligodendrocyte differentiation and myelination through intercellular self-interactions

  4. a novel role for LINGO-1 in neural stem cell differentiation to neurons

  5. inhibitory agents of LINGO-1 activity can protect dopaminergic neurons against degeneration

  6. Lingo1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis.

LINGO1 profil antigène

Profil protéine

May play a role in regulating axonal regeneration and plasticity in the adult central nervous system (By similarity).

Gene names and symbols associated with LINGO1

  • leucine rich repeat and Ig domain containing 1 (LINGO1) anticorps
  • leucine rich repeat and Ig domain containing 1 (lingo1) anticorps
  • leucine rich repeat and Ig domain containing 1 (Lingo1) anticorps
  • 4930471K13Rik anticorps
  • AV148400 anticorps
  • DKFZp459P0736 anticorps
  • LERN1 anticorps
  • LINGO-1 anticorps
  • Lrrn6a anticorps
  • UNQ201 anticorps

Protein level used designations for LINGO1

leucine rich repeat and Ig domain containing 1 , leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 , Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 , leucine rich repeat neuronal 6A , leucine-rich repeat and immunoglobilin domain-containing protein 1 , leucine-rich repeat and immunoglobulin domain-containing protein 1 , leucine-rich repeat neuronal protein 1 , leucine-rich repeat neuronal protein 6A , leucine-rich repeat neuronal 6A , cLINGO-1

GENE ID SPECIES
453764 Pan troglodytes
100061441 Equus caballus
100101739 Xenopus (Silurana) tropicalis
100171931 Pongo abelii
100228050 Taeniopygia guttata
84894 Homo sapiens
235402 Mus musculus
415344 Gallus gallus
487660 Canis lupus familiaris
100155465 Sus scrofa
520694 Bos taurus
315691 Rattus norvegicus
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