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MVP encodes the major component of the vault complex. De plus, nous expédions Major Vault Protein Kits (34) et Major Vault Protein Protéines (7) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 198 products:
Cow (Bovine) Monoclonal MVP Primary Antibody pour IF, IP - ABIN968013
Kickhoefer, Rome: The sequence of a cDNA encoding the major vault protein from Rattus norvegicus. dans Gene 1995
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Fish Polyclonal MVP Primary Antibody pour IF (p), IHC (p) - ABIN671586
Hu, Peng, Li: The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer. dans Journal of experimental & clinical cancer research : CR 2009
Show all 3 Pubmed References
Human Monoclonal MVP Primary Antibody pour IF, IHC (p) - ABIN564285
Rahimi, Wilson, Saylor, Stelow, Thomas, Reibel, Levine, Shonka, Jameson, Read: p16, Cyclin D1, and HIF-1? Predict Outcomes of Patients with Oropharyngeal Squamous Cell Carcinoma Treated with Definitive Intensity-Modulated Radiation Therapy. dans International journal of otolaryngology 2012
Major vault protein is important in the drug resistance of cancer cells, but it requires the presence of vPARP (Montrer PARP4 Anticorps) for full activity
Study found significant upregulation of MVP and BCRP whereas MRP1 (Montrer MDM4 Anticorps) and UGT1A4 (Montrer UGT1A4 Anticorps) were unaltered in drug resistant epilepsy brains. While upregulation of BCRP was significantly higher in mesial temporal lobe epilepsy (9.34+/-0.45; p<0.05), upregulation of MVP was significantly higher in focal cortical dysplasia (2.94+/-0.65; p<0.01).
Taxus chinensis var.-mediated downregulation of MRP1 (Montrer MDM4 Anticorps), MDR1 (Montrer TBC1D9 Anticorps), and LRP (Montrer RPSA Anticorps) might contribute to the reversal of drug resistance in non-small cell lung cancer stem cells.
We believe that for the first time, genetic variants at XRCC6 (Montrer XRCC6 Anticorps) and MVP genes are associated with risk of more aggressive disease, and would be taken into account when assessing the malignancy of prostate cancer
MVP genetic polymorphisms and haplotypes may not be associated with drug resistance of partial epilepsy in the Chinese Han population.
NSCLCs [ non-small cell lung cancer ] expressing P-gp (Montrer ABCB4 Anticorps) [P-glycoprotein ]/LRP (Montrer RPSA Anticorps) [ lung resistance-related protein] bear the EGFR (Montrer EGFR Anticorps) [epidermal growth factor receptor (Montrer EGFR Anticorps)] mutation in exon 19 or 21 easily.
The association of MVP amplification and PTEN deletion could be a potential biomarker in glioblastoma.
Bag3 (Montrer BAG3 Anticorps)-MVP is an important complex that regulates a potent prosurvival signaling pathway and contributes to chemotherapy resistance in breast cancer
LDL increases ABCB1 (Montrer ABCB1 Anticorps), ABCC1 (Montrer ABCC1 Anticorps), and LRP (Montrer RPSA Anticorps) expression in a human doxorubicin-resistant uterine sarcoma cell line.
Study demonstrates that vaults have a tumour-promoting potential by stabilizing EGFR (Montrer EGFR Anticorps)/PI3K (Montrer PIK3CA Anticorps)-mediated migration and survival pathways in human glioblastoma.
MVP may fine-tune SR-A (Montrer MSR1 Anticorps) activity in macrophages which contributes to the development of atherosclerosis
MVP is hijacked by L. monocytogenes in order to counteract the autophagy process, a finding that could have major implications in deciphering the cellular role of vault particles.
These results suggest that up-regulation of MVP in multi-drug resistance (MDR) may involve chromatin remodeling.
Results suggest that major vault protein functions as a novel scaffold protein (Montrer HOMER1 Anticorps) for both SHP-2 (Montrer PTPN11 Anticorps) and Erk (Montrer EPHB2 Anticorps).
results suggest that MVP makes a substantial contribution to epithelial cell-mediated resistance to infection
The crystal structure of the vault particle solved at 8 A resolution, together with the 2.1-A structure of the seven N-terminal domains (R1-R7) of MVP, provide an explanation for a reversible dissociation induced by low pH.
MVP is beneficial for functional recovery and axonal regrowth after spinal cord injury in adult zebrafish.
structure and cellular localization during embryonic development; findings indicate a dramatic relocalization of MVP from the cytoplasm to the nucleus during sea (Montrer Slc25a1 Anticorps) urchin embryogenesis
This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.
lung resistance-related protein
, major vault protein
, lung resistance-associated protein