anti-Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT2) Anticorps

The product of MGAT2 is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. De plus, nous expédions MGAT2 Kits (12) et MGAT2 Protéines (11) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
MGAT2 4247 Q10469
MGAT2 94273 Q09326
MGAT2 217664 Q921V5
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Top anti-MGAT2 Anticorps sur

Showing 10 out of 63 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-MGAT2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  293T cell lysate MGAT2 is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells 100 μL 2 to 3 Days
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-MGAT2 Antibody Titration:  1.25ug/ml  Positive Control:  Jurkat cell lysate Human kidney 100 μL 2 to 3 Days
Roussette (Chauve-souris) Lapin Inconjugué IHC, IHC (p), WB 100 μL 11 to 14 Days
Roussette (Chauve-souris) Lapin Inconjugué WB 100 μL 11 to 14 Days
Humain Lapin Inconjugué FACS, WB Western blot analysis in MCF-7?HepG2 cell line lysates (35ug/lane). Flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL 2 to 3 Days
Humain Lapin Inconjugué WB Western blot analysis of extracts of Human liver cells, using MGAT2 antibody. 100 μL 11 to 13 Days
Chien Lapin Inconjugué IHC, ELISA, WB 100 μL 2 to 3 Days
Humain Lapin APC IHC, ELISA   200 μL 11 to 14 Days
Humain Lapin Alkaline Phosphatase (AP) IHC, ELISA   200 μL 11 to 14 Days
Humain Lapin FITC IHC, ELISA   200 μL 11 to 14 Days

anti-MGAT2 Anticorps mieux référencés

  1. Human Polyclonal MGAT2 Primary Antibody pour IHC (p), ELISA - ABIN545233 : Tan, Dunn, Jaeken, Schachter: Mutations in the MGAT2 gene controlling complex N-glycan synthesis cause carbohydrate-deficient glycoprotein syndrome type II, an autosomal recessive disease with defective brain development. dans American journal of human genetics 1996 (PubMed)
    Show all 3 Pubmed References

Plus d’anticorps contre MGAT2 partenaires d’interaction

Human Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT2) interaction partners

  1. The recombinant hGnTII was purified from silkworm larval hemolymph in two steps by using tandem affinity purification tags, with a yield of approximately 120 mug from 10 mL hemolymph, and exhibited glycosyltransferase activity and strict substrate specificity. The enzyme was found to be N-glycosylated by the enzymatic cleavage of glycans, while hGnTII expressed in insect cells had not been reported to be glycosylated.

  2. These data suggest that substrate binding by MGAT2 employs both conserved and convergent catalytic subsite modules to provide substrate selectivity and catalysis. More broadly, the MGAT2 active-site architecture demonstrates how glycosyltransferases create complementary modular templates for regiospecific extension of glycan structures in mammalian cells.

  3. UDP-galactose (SLC35A2) and UDP-N-acetylglucosamine (SLC35A3) Transporters Form Glycosylation-related Complexes with Mannoside Acetylglucosaminyltransferases (Mgats).

  4. Golgi N-glycosyltransferases beta-1,2-N-acetylglucosaminyltransferase I, beta-1,2-N-acetylglucosaminyltransferase II, 1,4-galactosyltransferase I, and alpha-2,6-sialyltransferase I form both homo- and heterodimeric enzyme complexes in live cells

Mouse (Murine) Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT2) interaction partners

  1. the CD11c promoter was unexpectedly active and triggered Mgat2 deletion within multiple hematopoietic lineages, showed remarkably poor penetrance within native DC populations, and produced almost undetectable levels of green fluorescent protein signal. These findings show that the CD11c promoter is not DC-specific, and extreme care should be taken in the interpretation of data using any mouse created using the CD11c-CRE

  2. when the C-terminal cysteine (C334) was mutated, MGAT activity was actually higher than that of wild-type FL-MGAT2. Lastly, we determined that both transmembrane domains of MGAT2 are important for its ER localization, and that MGAT2 is present in mitochondrial-associated membranes.

  3. The use of 1-oleoyl-glycerol-d5 and (U13)C-TG oil followed by LC/ESI/MS/MS detection of stable-isotopic labeled DAG, TG, or glycerol provides a wide range of applications to study pathophysiological regulation of the monoacylglycerol pathway and MGAT2 activity.

  4. beneficial effects of vertical sleeve gastrectomy on body weight and glucose metabolism are independent of MGAT2 activity

  5. The results suggest that MGAT2 has a pivotal role in lipid metabolism in the small intestine, and the inhibition of MGAT2 activity may be a promising strategy for the treatment of obesity-related metabolic disorders.

  6. MGAT2 may play an important role in dietary fat absorption

  7. MGAT2 is a monoacylglycerol acyltransferase expressed in the small intestine

  8. investigated the expression of murine MGAT2 protein along the intestinal tract, determined its subcellular localization, and studied its regulation by diet and in db/db mouse

  9. analysis of developmental and nutritional regulation of monoacylglyceanalysis of developmental and nutritional regulation of monoacylglycerol lipase and monoacylglycerol acyltransferaserol lipase and monoacylglycerol acyltransferase

MGAT2 profil antigène

Profil protéine

The product of this gene is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in this gene may lead to carbohydrate-deficient glycoprotein syndrome, type II. The coding region of this gene is intronless. Transcript variants with a spliced 5' UTR may exist, but their biological validity has not been determined.

Gene names and symbols associated with MGAT2

  • mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (MGAT2) anticorps
  • CG7921 gene product from transcript CG7921-RB (Mgat2) anticorps
  • mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase L homeolog (mgat2.L) anticorps
  • mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (mgat2) anticorps
  • mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (Mgat2) anticorps
  • mannoside acetylglucosaminyltransferase 2 (Mgat2) anticorps
  • AA407964 anticorps
  • CDG2A anticorps
  • CDGS2 anticorps
  • CG7921 anticorps
  • CH73-301C19.1 anticorps
  • Dmel\\CG7921 anticorps
  • dMGAT2 anticorps
  • GlcNAc-TII anticorps
  • GlcNAcT2 anticorps
  • GLCNACTII anticorps
  • GNT-II anticorps
  • Gnt2 anticorps
  • MGC89475 anticorps
  • zgc:162268 anticorps

Protein level used designations for MGAT2

Beta-1,2-N-acetylglucosaminyltransferase II , N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II , UDP-N-acetylglucosamine:alpha-6-D-mannoside beta-1,2-N-acetylglucosaminyltransferase II , alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase , glcNAc-T II , mannoside acetylglucosaminyltransferase 2 , CG7921-PA , CG7921-PB , CG7921-PC , Mgat2-PA , Mgat2-PB , Mgat2-PC , mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase , alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase-like , GNT-II , beta-1,2-N-acetylglucosaminyltransferase II , beta-12-N-acetylglucosaminyltransferase II

4247 Homo sapiens
43563 Drosophila melanogaster
414590 Xenopus laevis
448439 Xenopus (Silurana) tropicalis
480312 Canis lupus familiaris
706426 Macaca mulatta
740608 Pan troglodytes
100023862 Monodelphis domestica
100348676 Oryctolagus cuniculus
100403225 Callithrix jacchus
100460559 Pongo abelii
100469937 Ailuropoda melanoleuca
94273 Rattus norvegicus
100151745 Sus scrofa
217664 Mus musculus
101122525 Ovis aries
100724305 Cavia porcellus
100000478 Danio rerio
Fournisseurs de qualité sélectionnés pour anti-MGAT2 (MGAT2) Anticorps
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