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MEIS2 encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. De plus, nous expédions MEIS2 Protéines (6) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 93 products:
Human Monoclonal MEIS2 Primary Antibody pour IF, IHC (p) - ABIN561794
García-Moreno, Pedraza, Di Giovannantonio, Di Salvio, López-Mascaraque, Simeone, De Carlos: A neuronal migratory pathway crossing from diencephalon to telencephalon populates amygdala nuclei. dans Nature neuroscience 2010
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Human Polyclonal MEIS2 Primary Antibody pour ICC, IF - ABIN4333477
He, Ebarasi, Zhao, Guo, Ojala, Hultenby, De Val, Betsholtz, Tryggvason: Lmx1b and FoxC combinatorially regulate podocin expression in podocytes. dans Journal of the American Society of Nephrology : JASN 2014
Human Polyclonal MEIS2 Primary Antibody pour ELISA, WB - ABIN4333476
Mercader, Leonardo, Azpiazu, Serrano, Morata, Martínez, Torres: Conserved regulation of proximodistal limb axis development by Meis1/Hth. dans Nature 1999
Cow (Bovine) Polyclonal MEIS2 Primary Antibody pour IHC, WB - ABIN2775951
Yang, Hwang, DSouza, Lee, Junn, Mouradian: Three-amino acid extension loop homeodomain proteins Meis2 and TGIF differentially regulate transcription. dans The Journal of biological chemistry 2000
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High expression of MEIS2 impairs repressive DNA binding of AML1 (Montrer RUNX1 Anticorps)-ETO, inducing increased expression of genes such as the druggable proto-oncogene (Montrer RAB1A Anticorps) YES1 (Montrer YES1 Anticorps).
we have identified a novel nonsense MEIS2 mutation in a female patient with cleft palate, cardiac septal defect, severe ID, developmental delay and feeding difficulty with gastro-esophageal reflux. Our findings strongly suggest neurocristopathy be included in the clinical features associated with MEIS2 alterations.
Meis2 as the target of miR (Montrer MLXIP Anticorps)-134 in the regulation of cardiomyocyte progenitor cell proliferation.
This is the first report showing a de novo small intragenic mutation in MEIS2 and further confirms the important role of this gene in normal development.
Our results show that MEIS2 is a gene needed for palate closure. In syndromic cases of cleft palate, MEIS2 should be considered among the candidate genes, for example, in cases without 22q11.2 deletions.
FOXM1 (Montrer FOXM1 Anticorps) is a direct target gene of MEIS2 and is required for MEIS2 to upregulate mitotic genes.
The data suggest existence of a complex regulatory pathway in the trabecular meshwork part of which includes interactions between FOXC1 (Montrer FOXC1 Anticorps), miR (Montrer MLXIP Anticorps)-204, MEIS2, and ITGbeta1.
Klf4 (Montrer KLF4 Anticorps) recruits a complex of Meis and Pbx proteins to DNA, resulting in Meis2 transcriptional activation domain-dependent activation of a subset of Klf4 (Montrer KLF4 Anticorps) target genes.
The Single Nucleotide Polymorphism in Meis homeobox 2 (MEIS2) mediated the effects of risperidone on hip circumference (q=0.004).
Transgenic mice lacking microRNAs miR (Montrer MLXIP Anticorps)-9-2 and miR (Montrer MLXIP Anticorps)-9-3 exhibit multiple defects of telencephalic structures which may be brought about by dysregulation of Foxg1 (Montrer FOXG1 Anticorps), Nr2e1 (Montrer NR2E1 Anticorps), Gsh2 (Montrer GSX2 Anticorps), and Meis2 expression.
MEIS2 associates with chromatin-bound PBX1 (Montrer PBX1 Anticorps), recruits PARP1/ARTD1 (Montrer PARP1 Anticorps), and initiates PARP1 (Montrer PARP1 Anticorps)-mediated eviction of H1 from the chromatin fiber.
An intrinsic constitutively activated feedforward signaling circuit composed of IkappaBalpha (Montrer NFKBIA Anticorps)/NF-kappaB (Montrer NFKB1 Anticorps)(p65 (Montrer NFkBP65 Anticorps)), miR (Montrer MLXIP Anticorps)-196b-3p, Meis2, and PPP3CC (Montrer PPP3CC Anticorps) is formed during the emergence of castration-resistant prostate cancer.
Hoxa2, Meis and Pbx proteins act cooperatively on the ECR, via a core 32 bp sequence, to regulate Hmx1 expression.
We found that expression of Emx2 (Montrer EMX2 Anticorps) and Lhx2 (Montrer LHX2 Anticorps) initiated between neuronal progenitor and neuronal precursor stages. As far as the sensory neurons of the vomeronasal organ are concerned, Meis1 (Montrer MEIS1 Anticorps) and Meis2 were only expressed in the apical layer, together with Gnai2 (Montrer GNAI2 Anticorps), but not in the basal layer.
we show that simultaneous deletion of Meis1 (Montrer MEIS1 Anticorps) and Meis2 in presumptive lens ectoderm results in arrested lens development in the pre-placodal stage, and neither lens placode nor lens is formed. We found that in the presumptive lens ectoderm of Meis1 (Montrer MEIS1 Anticorps)/Meis2 deficient embryos Pax6 (Montrer PAX6 Anticorps) expression is absent
Meis2-null mice are embryonic lethal. The results reveal a critical role of Meis2 during cranial and cardiac neural crest cells development in mouse.
Data suggest that the RING1 (Montrer RING1 Anticorps)-MEIS1 (Montrer MEIS1 Anticorps)/2 axis is regulated by early PD signals and contributes to the initiation or maintenance of the distal signal circuitry.
Interaction of Meis2 promoter with midbrain enhancer depends on RING1.
Meis2 cooperates with Pax6 (Montrer PAX6 Anticorps) in generic neurogenesis and dopaminergic fate specification in the adult subventricular zone-olfactory bulb system.
These data identify Meis2 as a marker for the study of amacrine cell diversity and development in addition to providing evidence for the stepwise specification of the glycinergic and GABAergic neurotransmitter phenotypes during AM cell differentiation.
This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcription regulators, and several members have been shown to be essential contributors to developmental programs. Multiple transcript variants encoding distinct isoforms have been described for this gene.
Meis homolog 2
, Meis1, myeloid ecotropic viral integration site 1 homolog 2
, Meis1-related gene 1
, TALE homeobox protein Meis2
, homeobox protein Meis2
, meis1-related protein 1
, Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2
, myeloid ecotropic viral integration site-related gene 1
, homeoprotein Meis2a.1
, homeoprotein Meis2a.2
, myeloid ecotropic viral insertion site-2a protein
, XMeis1-3 protein
, Meis homeobox 2
, homeobox protein Meis2-like