N-Acetyltransferase 8-Like (GCN5-Related, Putative) Protéines (NAT8L)

NAT8L encodes a single-pass membrane protein, which contains a conserved sequence of the GCN5 or NAT superfamily of N-acetyltransferases and is a member of the N-acyltransferase (NAT) superfamily. De plus, nous expédions N-Acetyltransferase 8-Like (GCN5-Related, Putative) Anticorps (26) et N-Acetyltransferase 8-Like (GCN5-Related, Putative) Kits (18) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
NAT8L 269642 Q3UGX3
Rat NAT8L NAT8L 289727 D3ZVU9
NAT8L 339983 Q8N9F0
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Top N-Acetyltransferase 8-Like (GCN5-Related, Putative) Protéines sur anticorps-enligne.fr

Showing 4 out of 5 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Souris rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Connectez-vous pour afficher 50 to 55 Days
$5,355.45
Détails
Cellules d'insectes Humain rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Connectez-vous pour afficher 50 to 55 Days
$7,626.01
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
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Escherichia coli (E. coli) Humain T7 tag,His tag 100 μg Connectez-vous pour afficher 15 to 18 Days
$698.00
Détails

NAT8L Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Mouse (Murine)

Human , ,
, ,

Plus protéines pour N-Acetyltransferase 8-Like (GCN5-Related, Putative) (NAT8L) partenaires d'interaction

Mouse (Murine) N-Acetyltransferase 8-Like (GCN5-Related, Putative) (NAT8L) interaction partners

  1. The findings of this study indicated that the striatal expression of N-acetylaspartate synthetase Shati/Nat8l plays a role in major depressive disorder via the metabotropic glutamate receptor 3 (Montrer GRM3 Protéines)-mediated functional control of the serotonergic neuronal system.

  2. Results showed that the Shati/Nat8L mRNA was increased by methamphetamine-induced CREB (Montrer CREB1 Protéines) pathway via dopamine D1 receptor (Montrer DRD1 Protéines) signaling in mouse nucleus accumbens. These findings may contribute to development of a clinical tool for methamphetamine addiction.

  3. Results showed that both Shati+/- and Shati-/- mice demonstrated lower levels of NAA in the brain than Shati+/+ mice, suggesting that SHATI predominantly regulates NAA content in the brain

  4. Study shows that Shati/Nat8l in the neuron may induce axon outgrowth by ATP synthesis and not through mGluR3 (Montrer GRM3 Protéines) signaling.

  5. Dysregulated expression of Nat8L is associated with deficits in oxidative phosphorylation in 5xFAD model of Alzheimer disease.

  6. results indicate that Shati/Nat8l in the Nucleus Accumbens, but not in the dorsal striatum, plays a suppressive role in the behavioral responses to METHamphetamine by controlling the dopaminergic system via activation of group II mGlutamate receptors

  7. The results of this study showed that Deletion of NAT8L increases dopamine D1 receptor on the cell surface in the nucleus accumbens, accelerating methamphetamine dependence in mice.

  8. Nat8l impacts on the brown adipogenic phenotype

  9. Deficiency of SHATI may affect behavior.

  10. shati expression affects emoutional behaivors in mice

Human N-Acetyltransferase 8-Like (GCN5-Related, Putative) (NAT8L) interaction partners

  1. Nat8l CpG island methylation ratios were lower in the patients with schizophrenia than in the healthy controls.

  2. Characterization and recombinant expression of the nat8l gene that codes for ANAT.

  3. NAA is produced specifically in NSCLC tumors through NAT8L overexpression, and its extracellular secretion can be detected in blood

  4. This study demonistrated that the human NAT8L gene related to reward dependence, a personality trait, and grey matter volume in the caudate nucleus in healthy subjects, suggesting that NAT8L might also affect human personality

  5. Nat8l impacts on the brown adipogenic phenotype

  6. Results indicated that NAT8L, but not NAT14 (Montrer NAT14 Protéines), catalysed the synthesis of NAA from L-aspartate and acetyl-CoA (Montrer LPCAT2 Protéines).

Profil protéine N-Acetyltransferase 8-Like (GCN5-Related, Putative) (NAT8L)

Profil protéine

This gene encodes a single-pass membrane protein, which contains a conserved sequence of the GCN5 or NAT superfamily of N-acetyltransferases and is a member of the N-acyltransferase (NAT) superfamily. This protein is a neuron-specific protein and is the N-acetylaspartate (NAA) biosynthetic enzyme, catalyzing the NAA synthesis from L-aspartate and acetyl-CoA. NAA is a major storage and transport form of acetyl coenzyme A specific to the nervous system. The gene mutation results in primary NAA deficiency (hypoacetylaspartia).

Gene names and symbols associated with NAT8L

  • N-acetyltransferase 8 like (NAT8L)
  • N-acetyltransferase 8-like (nat8l)
  • N-acetyltransferase 8-like protein (HPB8_615)
  • N-acetyltransferase 8-like (GCN5-related, putative) (nat8l)
  • N-acetyltransferase 8-like (Nat8l)
  • 1110038O08Rik Protéine
  • CML3 Protéine
  • NACED Protéine
  • NAT8-LIKE Protéine
  • RGD1305719 Protéine
  • sb:cb562 Protéine
  • Shati Protéine
  • zgc:162648 Protéine

Protein level used designations for NAT8L

N-acetyltransferase 8-like , N-acetylaspartate synthetase , N-acetyltransferase 8-like protein , NAA synthetase , camello 3 , protein Shati , camello-like protein 3

GENE ID SPECIES
422893 Gallus gallus
564754 Danio rerio
9349254 Helicobacter pylori B8
100124940 Xenopus (Silurana) tropicalis
269642 Mus musculus
289727 Rattus norvegicus
339983 Homo sapiens
612955 Canis lupus familiaris
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