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Required for vesicle-mediated transport. De plus, nous expédions NSF Anticorps (122) et NSF Protéines (9) et beaucoup plus de produits pour cette protéine.
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A large copy number variant (CNV) that encompasses part of the NSF gene contributes to cocaine dependence.
NSF deficiency in HeLa cells barely affected cell viability, anterograde trafficking of vesicular stomatitis virus glycoprotein G and transferrin endocytosis.
a processive helicase-like mechanism for NSF in which approximately 1 residue is unwound for every hydrolyzed ATP molecule.
Single and multiple-marker analyses revealed a strong association between cocaine dependence and the NSF gene.
Knockdown of TRX1 increases the level of S-nitrosylated NSF, prolongs the inhibition of exocytosis, and suppresses leukocyte
NSF independent fusion of Salmonella-containing late phagosomes with early endosomes.
analysis of human NSF possible binding mode to GABARAP and GATE-16
binding of NSF to GluR2-containing AMPARs in stabilizing these receptors in the synaptic membrane and impeding their regulated endocytosis.
role of interaction with GluR2 in regulation of AMPA receptors by brain-derived neurotrophic factor
Nitric oxide regulates exocytosis by S-nitrosylation of NSF.
Expressing a biochemically defined NSF mutant that lacks ATPase activity results in a dramatic inhibition of stimulated mast cell exocytosis.
NSF dissociates the VAMP-2.SNAP-25.syntaxin 13 complex, but has no effect on the Hrs-containing complex.
Pctaire1 phosphorylates N-ethylmaleimide-sensitive fusion protein
dual regulation on hbeta2AR trafficking and signaling by NSF through direct binding to cargo receptor and its ATPase activity.
Data show that NSF is an inclusion body component in neuronal intranuclear inclusion disease identified by anti-SUMO-1-immunocapture.
Data show that phosphorylation of N-ethylmaleimide-sensitive factor on tyrosine residues prevents its SNARE complex dissociation activity and establish a role for PTP1B in the modulation of the membrane fusion machinery.
Munc13-1 and Munc18-1, but not CAPS-1/2, stabilize primed synaptic vesicles by preventing NSF-dependent de-priming.
NSF may have a role in vascular instability in gram-positive lung infections
that mutant LRRK2 may impair synaptic vesicle dynamics via aberrant phosphorylation of N-ethylmaleimide sensitive fusion
identify conserved sequences in the 3'UTR of NSF as miR-33 responsive elements and show that Nsf is specifically recruited to the RNA-induced silencing complex following induction of miR-33
Arr1 and NSF interaction are necessary for both maintenance and modulation of normal photoreceptor synaptic regulation and NSF-RP2 interaction may play an important role in membrane protein trafficking in the photoreceptor.
These findings identify new roles for N-ethylmaleimide-sensitive factor and protein kinase C epsilon in regulating synaptic inhibition through downregulation of GABA(A) receptors
interaction of AMPA receptors with N-ethylmaleimide-sensitive factor plays a critical role in incorporation of AMPA receptors into synapses and for their subsequent removal during cerebellar long term depression
PICK1 and NSF dynamically regulate the synaptic delivery of GluR2-containing receptors during CARP and thus regulate the calcium permeability of AMPA receptors at excitatory synapses.
H(2)O(2) regulates exocytosis by inhibiting N-ethylmaleimide sensitive factor (NSF), a protein that regulates membrane fusion events necessary for exocytosis.
important role for NSF activity in regulating the cell surface stability of GABA(A) receptors.
These results indicate that phosphorylation of GluR2 S880 and NSF and PICK1 binding to GluR2 dynamically regulate GluR2 recycling.
Nitric oxide regulates exocytosis by S-nitrosylation of N-ethylmaleimide sensitive factor
Report depletion of the ATPase NSF from Golgi membranes with hypo-S-nitrosylation of vasorelevant proteins in endothelial cells exposed to monocrotaline pyrrole.
NSF- and SNARE-mediated membrane fusion events are essential steps during Nuclear envelope formation downstream of Nup107 recruitment, and upstream of membrane flattening and completion of nuclear pore complex assembly.
Molecular analysis of ndrg4 mutants shows that expression of snap25 and nsf are sharply decreased, revealing a role of ndrg4 in controlling vesicle exocytosis. This uncovers a previously unknown function of ndrg4 in regulating vesicle docking and nodes of Ranvier organization, at least through its ability to finely tune the expression of the t-SNARE/NSF machinery.
results establish a role for Nsf in the maintenance of synaptic contacts between hair cells and afferent neurons, mediated in part via the secretion of trophic signaling factors
Nsf is essential in the formation of the nodes of Ranvier in the vertebrate nervous system.
Activation of PKCgamma is necessary for the activity-dependent trafficking of AMPARs in embryonic zebrafish and is NMDA and SNARE-dependent and requires AMPARs to associate with both NSF and PICK1.
This study analyses of nsf mutant zebrafish reveal an unexpected role for NSF in hypothalamic development, with mutant 5 days post-fertilization larvae exhibiting a stage-dependent loss of neuroendocrine transcripts.
The mutant phenotype to the missense mutation D374N in the NSF gene, encoding the N-ethylmaleimide-sensitive factor, was linked a key component of membrane fusion.
Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seem to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling (By similarity).
N-ethylmaleimide-sensitive factor-like protein
, N-ethylmaleimide-sensitive fusion protein
, NEM-sensitive fusion protein
, vesicle-fusing ATPase
, vesicular-fusion protein NSF
, N-ethylmaleimide sensitive factor
, suppressor of K(+) transport growth defect 2
, N-ethylmaleimide sensitive fusion protein
, N-ethylmaleimide-sensitive factor
, vesicle-fusing ATPase-like
, Vesicle-fusing ATPase
, Vesicular-fusion protein NSF