Peroxisome Proliferator-Activated Receptor Gamma, Coactivator-Related 1 (PPRC1) Kits ELISA

The protein encoded by PPRC1 is similar to PPAR-gamma coactivator 1 (PPARGC1/PGC-1), a protein that can activate mitochondrial biogenesis in part through a direct interaction with nuclear respiratory factor 1 (NRF1). De plus, nous expédions PPRC1 Anticorps (35) et et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
PPRC1 226169 Q6NZN1
PPRC1 23082 Q5VV67
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Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain 0.078 ng/mL 0.156-10 ng/mL   96 Tests 2 to 3 Days
$713.90
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Souris
  96 Tests 15 to 18 Days
$875.60
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Plus Kits ELISA pour PPRC1 partenaires d'interaction

Mouse (Murine) Peroxisome Proliferator-Activated Receptor Gamma, Coactivator-Related 1 (PPRC1) interaction partners

  1. these results indicated an elevated basal metabolic rate and lipid metabolic alteration of male Pprc1(+/-) mice on high-fat diet, suggesting the significant role of Pprc1 in controlling mitochondrial gene expression and energy metabolic processes

  2. Homozygous deficient PPRC1 mice failed to form egg cylinders and died after implantation but before embryonic day 6.5, whereas mice heterozygous for PPRC1 were viable, fertile and indistinguishable from their wild-type littermates.

Human Peroxisome Proliferator-Activated Receptor Gamma, Coactivator-Related 1 (PPRC1) interaction partners

  1. PRC and c-MYC can act in concert through Akt-GSK-3 signaling to reprogram gene expression in response to mitochondrial stress.

  2. PRC is a negative regulator of endothelial inflammation; it negatively regulates endothelial adhesion of monocytes via inhibition of NF kappaB activity

  3. A general role for PRC in the adaptive response to cellular dysfunction.

  4. PRC has a role in the rapid modulation of metabolic functions in response to the status of the cell cycle

  5. overexpression of the PRC pathway is responsible for mitochondrial proliferation in the context of thyroid oncocytoma

  6. PGC-1 has a role in regulating gluconeogenic genes along with HNF-4alpha and SREBP-1

  7. This review focuses on the biologic and physiologic functions of the PGC-1 coactivators, with particular emphasis on striated muscle, liver, and other organ systems relevant to common diseases such as diabetes and heart failure.

  8. Upregulation of PGC-1alpha and PGC-1beta in the colorectal tumor cells can be part of an adaptation mechanism to help overcome the severe consequences of mtDNA mutations on oxidative phosphorylation.

  9. These results revealed that bile acid inhibits the promoter activity of PGC-1 in an SHP-dependent manner.

  10. Activation of the SIRT1/PGC-1 pathway, in a metabolic context promotes mitochondrial function and this pathway plays a role in neurodegerative disease. Review.

  11. The results are consistent with a pathway whereby PRC regulates NRF-2-dependent genes through a multiprotein complex involving HCF-1.

  12. support a role for PRC in the integration of pathways directing mitochondrial respiratory function and cell growth

  13. Coordinate regulation of nucleus-encoded mitochondrial transcription factors by NRFs and PGC-1 family coactivators is essential to the control of mitochondrial biogenesis

  14. PRC is a functional relative of PGC-1 that operates through NRF-1 and possibly other activators in response to proliferative signals

PPRC1 profil antigène

Antigen Summary

The protein encoded by this gene is similar to PPAR-gamma coactivator 1 (PPARGC1/PGC-1), a protein that can activate mitochondrial biogenesis in part through a direct interaction with nuclear respiratory factor 1 (NRF1). This protein has been shown to interact with NRF1. It is thought to be a functional relative of PPARGC1 that activates mitochondrial biogenesis through NRF1 in response to proliferative signals.

Gene names and symbols associated with PPRC1

  • peroxisome proliferative activated receptor, gamma, coactivator-related 1 (Pprc1) anticorps
  • peroxisome proliferator-activated receptor gamma, coactivator-related 1 (PPRC1) anticorps
  • A930018M19 anticorps
  • BC013720 anticorps
  • mKIAA0595 anticorps
  • PRC anticorps
  • RP11-302K17.6 anticorps

Protein level used designations for PPRC1

PGC-1-related coactivator , peroxisome proliferator-activated receptor gamma coactivator-related protein 1 , PGC-1 related co-activator , peroxisome proliferative activated receptor, gamma, coactivator-related 1

GENE ID SPECIES
226169 Mus musculus
23082 Homo sapiens
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