Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) Kits ELISA

The protein encoded by PPP1R14A belongs to the protein phosphatase 1 (PP1) inhibitor family. De plus, nous expédions Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A Anticorps (59) et Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A Protéines (13) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
PPP1R14A 94274 Q96A00
PPP1R14A 114004 Q99MC0
PPP1R14A 68458 Q91VC7
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Plus Kits ELISA pour Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A partenaires d'interaction

Zebrafish Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) interaction partners

  1. Hoxb1b is likely to directly regulate ppp1r14al expression in rhombomere 4. Furthermore, ppp1r14al is essential for establishment of the earliest hindbrain signaling-center in rhombomere 4 by regulating expression of fgf3 (Montrer FGF3 Kits ELISA).

Human Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) interaction partners

  1. CPI-17 drives Ras activity and tumorigenesis in melanomas in a two-fold way; inactivation of the tumor suppressor merlin and activation of the growth promoting ERM family.

  2. The authors call the mutual sequestration mechanism through which pCPI-17 and myosin light-chain phosphatase interact inhibition by unfair competition: myosin light-chain phosphatase protects pCPI-17 from other phosphatases, while pCPI-17 blocks other substrates from the active site of myosin light-chain phosphatase.

  3. Study finds that CPI-17 (PPP1R14A protein phosphatase 1 regulatory inhibitor subunit 14A, 17 kDa) is not expressed in the healthy peripheral nervous system or in nontumour pathologies of the peripheral nervous system. CPI-17 up-regulation, however, is observed in over 90% of schwannomas, but not in neurofibroma and only rarely in malignant peripheral nerve sheath tumour.

  4. CPI-17 has a role in restoring skin homoeostasis in cutaneous field of cancerization lesions

  5. analysis of the interaction between plakoglobin (Montrer JUP Kits ELISA) and CPI-17, which is affected by the phosphorylation status of CPI-17 in human lung microvascular endothelial cells

  6. The N-terminal 21-residue tail domain of CPI-17 is necessary for nuclear localization. Phospho-mimetic Asp (Montrer ASIP Kits ELISA)-substitution of CPI-17 at Ser12 attenuates the nuclear import.

  7. The study characterized the CPI-17 promoter and identified binding sites for GATA-6 (Montrer GATA6 Kits ELISA) and nuclear factor kappa B (NF-kappaB (Montrer NFKB1 Kits ELISA)).

  8. a novel signaling cascade that links RhoA (Montrer RHOA Kits ELISA)-mediated calcium sensitivity to MEF2 (Montrer MEF2A Kits ELISA)-dependent myocardin (Montrer MYOCD Kits ELISA) expression in VSMCs through a mechanism involving p38 MAPK (Montrer MAPK14 Kits ELISA), PP1alpha (Montrer PPP1CA Kits ELISA), and CPI-17.

  9. RACK1 (Montrer GNB2L1 Kits ELISA) may play a role in PKC/CPI-17 signaling pathway.

  10. cAMP/PKA regulates the endothelial barrier via inhibition of the contractile machinery, mainly by the activation of MLCP via inhibition of CPI-17 and RhoA (Montrer RHOA Kits ELISA)/Rock.

Mouse (Murine) Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) interaction partners

  1. Enhanced vasorelaxation in early endotoxemia is mediated by redox signaling through PKG-1alpha but in later endotoxemia by myosin phosphatase isoform shifts enhancing sensitivity to NO/cGMP as well as smooth muscle atrophy.

  2. The study characterized the CPI-17 promoter and identified binding sites for GATA-6 (Montrer GATA6 Kits ELISA) and nuclear factor kappa B (NF-kappaB (Montrer NFKB1 Kits ELISA)).

  3. a novel signaling cascade that links RhoA (Montrer RHOA Kits ELISA)-mediated calcium sensitivity to MEF2 (Montrer MEF2C Kits ELISA)-dependent myocardin (Montrer MYOCD Kits ELISA) expression in VSMCs through a mechanism involving p38 MAPK (Montrer MAPK14 Kits ELISA), PP1alpha (Montrer PPP1CA Kits ELISA), and CPI-17.

  4. Data suggest that CPI-17 and both conventional and novel PKC isozymes contribute to the phasic and tonic contractile components of BALB/c colonic circular smooth muscle.

  5. Organ-specific mechanisms involving MYPT1 (Montrer PPP1R12A Kits ELISA), M-RIP, and CPI-17 are critical to regulating basal LC20 (Montrer MYL9 Kits ELISA) phosphorylation in gastrointestinal smooth muscles.

  6. calcium-independent phospholipase A2beta has a role in high glucose-induced activation of RhoA (Montrer RHOA Kits ELISA), Rho kinase (Montrer ROCK2 Kits ELISA), and CPI-17 in cultured vascular smooth muscle cells and vascular smooth muscle hypercontractility in diabetic animals

  7. distribution of mouse and rat PPP1R14A was more specific and different from that of humans

  8. concluded that actions downstream of cGMP/PKG (Montrer PRKG1 Kits ELISA) can reverse PKC (Montrer PKC Kits ELISA)-mediated phosphorylation of CPI-17 and Ca(2 (Montrer CA2 Kits ELISA)+) sensitization in smooth muscle

  9. findings suggest that CPI-17 was downregulated during intestinal inflammation and that TNF-alpha (Montrer TNF Kits ELISA) plays a central role in this process. Downregulation of CPI-17 may play a role in motility impairments in inflammation.

  10. CPI-17 expression is reversibly controlled in response to the phenotype transition of smooth muscle cells that restricts the signal to differentiated smooth muscle cells and particular cell types.

Pig (Porcine) Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) interaction partners

  1. This study examined the protein expression and spatial-temporal distribution of PKCalpha (Montrer PKCa Kits ELISA) and CPI-17 in intact smooth muscle tissues.

Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A) profil antigène

Antigen Summary

The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene names and symbols associated with PPP1R14A

  • protein phosphatase 1 regulatory inhibitor subunit 14A L homeolog (ppp1r14a.L) anticorps
  • protein phosphatase 1 regulatory inhibitor subunit 14A (ppp1r14a) anticorps
  • protein phosphatase 1, regulatory (inhibitor) subunit 14Aa (ppp1r14aa) anticorps
  • protein phosphatase 1 regulatory inhibitor subunit 14A (PPP1R14A) anticorps
  • protein phosphatase 1, regulatory (inhibitor) subunit 14A (PPP1R14A) anticorps
  • protein phosphatase 1, regulatory (inhibitor) subunit 14A (Ppp1r14a) anticorps
  • 1110001M11Rik anticorps
  • CPI-17 anticorps
  • Cpi17 anticorps
  • im:7147597 anticorps
  • MGC81874 anticorps
  • PPP1INL anticorps
  • PPP1R14A anticorps
  • zgc:110700 anticorps

Protein level used designations for PPP1R14A

protein phosphatase 1, regulatory (inhibitor) subunit 14A , protein phosphatase 1 regulatory subunit 14A , 17 kDa PKC-potentiated inhibitory protein of PP1 , 17-KDa protein , 17-kDa PKC-potentiated inhibitory protein of PP1 , PKC-potentiated inhibitory protein of PP1 , protein kinase C-potentiated inhibitor protein of 17 kDa , CPI-17

GENE ID SPECIES
447728 Xenopus laevis
493331 Xenopus (Silurana) tropicalis
550561 Danio rerio
612579 Canis lupus familiaris
615348 Bos taurus
641304 Ovis aries
747250 Pan troglodytes
94274 Homo sapiens
114004 Rattus norvegicus
68458 Mus musculus
397610 Sus scrofa
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