Purinergic Receptor P2X, Ligand-Gated Ion Channel, 6 Protéines (P2RX6)

The protein encoded by P2RX6 belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. De plus, nous expédions P2RX6 Anticorps (76) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
P2RX6 9127 O15547
P2RX6 18440 O54803
Rat P2RX6 P2RX6 25041 P51579
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Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Souris rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Connectez-vous pour afficher 50 to 55 Days
$5,355.45
Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,869.04
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P2RX6 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human
,
Mouse (Murine)
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Plus protéines pour Purinergic Receptor P2X, Ligand-Gated Ion Channel, 6 (P2RX6) partenaires d'interaction

Human Purinergic Receptor P2X, Ligand-Gated Ion Channel, 6 (P2RX6) interaction partners

  1. one subunit of P2X2 (Montrer P2RX2 Protéines) and two subunits of P2X3 (Montrer P2RX3 Protéines) form P2X2 (Montrer P2RX2 Protéines)/3 heteromeric receptors, whereas two subunits of P2X2 (Montrer P2RX2 Protéines) and one subunit of P2X6 constitute P2X2 (Montrer P2RX2 Protéines)/6 receptors

  2. Results show that P2X4 (Montrer P2RX4 Protéines) and P2X6 receptors are associated with VE-cadherin (Montrer CDH5 Protéines) at HUVEC adherens junctions.

Mouse (Murine) Purinergic Receptor P2X, Ligand-Gated Ion Channel, 6 (P2RX6) interaction partners

  1. purinergic signaling via P2X6 is not significantly involved in the regulation of renal electrolyte handling under normal physiological conditions.

  2. once inside the nucleus, P2X6 subunit interacts with the splicing factor 3A1 (Montrer SF3A1 Protéines), which ultimately results in a reduction of the mRNA splicing activity

  3. Immunoreactivity for P2X3 (Montrer P2RX3 Protéines)-, P2X5 (Montrer P2RX5 Protéines)-, and P2X6-purinoceptors was observed in mouse retina.

  4. This study provides the first evidence that P2X8 receptors are expressed on LHRH (Montrer GNRH1 Protéines)-containing neurons.

Profil protéine P2RX6

Profil protéine

The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified.

Gene names and symbols associated with P2RX6

  • purinergic receptor P2X 6 (P2RX6)
  • purinergic receptor P2X, ligand-gated ion channel, 6 (P2rx6)
  • P2X purinoceptor 6 (LOC100051842)
  • P2X purinoceptor 6 (LOC100588488)
  • purinergic receptor P2X 6 (P2rx6)
  • P2rxl1 Protéine
  • P2x6 Protéine
  • P2xm Protéine
  • Rnap2x6 Protéine

Protein level used designations for P2RX6

ATP receptor , P2X purinoceptor 6 , purinergic receptor P2X-like 1, orphan receptor , purinoceptor P2X6 , purinoreceptor P2X6 , skeletal muscle-expressed P2X , purinergic receptor P2X, ligand-gated ion channel, 6 , P2X purinoceptor 6-like , p2X purinoceptor 6-like , P2X6 receptor , P2XM , purinergic receptor P2X-like 1 orphan receptor , purinergic receptor P2X6

GENE ID SPECIES
9127 Homo sapiens
18440 Mus musculus
486436 Canis lupus familiaris
618262 Bos taurus
695841 Macaca mulatta
745626 Pan troglodytes
100051842 Equus caballus
100397824 Callithrix jacchus
100445728 Pongo abelii
100588488 Nomascus leucogenys
25041 Rattus norvegicus
100515342 Sus scrofa
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