Receptor Protein Tyrosine Phosphatase (PTPRT) Kits ELISA

The protein encoded by PTPRT is a member of the protein tyrosine phosphatase (PTP) family. De plus, nous expédions PTPRT Anticorps (35) et PTPRT Protéines (6) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
PTPRT 11122 O14522
PTPRT 19281 Q99M80
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Top PTPRT Kits ELISA sur anticorps-enligne.fr

Showing 2 out of 4 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain < 0.188 ng/mL 0.313 ng/mL - 20 ng/mL   96 Tests Connectez-vous pour afficher 11 to 18 Days
$810.17
Détails
Souris < 46.9 pg/mL 78 pg/mL - 5000 pg/mL   96 Tests Connectez-vous pour afficher 11 to 18 Days
$810.17
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Plus Kits ELISA pour PTPRT partenaires d'interaction

Human Receptor Protein Tyrosine Phosphatase (PTPRT) interaction partners

  1. The single cell genotyping not only confirmed the co-occurrence of the PTPRT, CAND1 and DOCK6 mutations in the same AML clone but also revealed a clonal hierarchy, as the PTPRT mutation was likely acquired after the CAND1 and DOCK6 mutations.

  2. PTPRT promoter methylation is significantly associated with sensitivity to STAT3 inhibition in HNSCC cells, suggesting that PTPRT promoter methylation may serve as a predictive biomarker for responsiveness to STAT3 inhibitors in clinical development

  3. Data reported evidence that rs2866943 polymorphism in PTPRT 3'-UTR was involved in the occurrence of esophageal squamous cell carcinoma by acting as a protective factor while rs6029959 acts as a risk factor.

  4. Data show that hepatitis B virus X protein mutant HBxDelta127 enhances proliferation of hepatoma cells through up-regulating miR-215 targeting protein tyrosine phosphatase, receptor type T (PTPRT).

  5. tumor-specific mutational events in the PTPRT gene can serve as direct drivers for tumor growth by inducing hyperactivation of STAT3, a potent oncogenic transcription factor and PTPRT substrate

  6. The catalytic domain point mutants show a decreased thermal and thermodynamic stability and decreased activation energy relative to phosphatase activity, when compared to wild- type

  7. [review] High-throughput mutational analysis identifies loss-of-function mutations in six PTPs in human colon cancers, providing critical cancer genetics evidence that PTPs can act as tumour suppressor genes.

  8. Data show that paxillin is a direct substrate of PTPRT and that PTPRT specifically regulates paxillin phosphorylation at tyrosine residue 88(Y88).

  9. alterations of the PTPRT-mediated signaling pathway by PTPRT phosphatase domain mutation may not play a critical role in the development of common human cancers

  10. STAT3 is a substrate of receptor protein tyrosine phosphatase T

  11. brain-specific PTPRT regulates synapse formation through interaction with cell adhesion molecules, and this function and the phosphatase activity are attenuated through tyrosine phosphorylation by the synaptic tyrosine kinase Fyn.

Mouse (Murine) Receptor Protein Tyrosine Phosphatase (PTPRT) interaction partners

  1. Receptor protein tyrosine phosphatase rho (RPTPrho, gene symbol PTPRT) is a transmembrane protein expressed at high levels in the developing hippocampus, olfactory bulb, cortex, and cerebellum.

  2. These studies implicate PTPRT-modulated STAT3 signaling in the regulation of high-fat diet-induced obesity

  3. BCR is a novel substrate of PTPRT .

  4. Data show that paxillin is a direct substrate of PTPRT and that PTPRT specifically regulates paxillin phosphorylation at tyrosine residue 88(Y88).

PTPRT profil antigène

Antigen Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of this PTP suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.

Gene names and symbols associated with PTPRT

  • protein tyrosine phosphatase, receptor type T (PTPRT) anticorps
  • protein tyrosine phosphatase, receptor type, T (Ptprt) anticorps
  • mKIAA0283 anticorps
  • RPTP-rfo anticorps
  • RPTPrho anticorps

Protein level used designations for PTPRT

R-PTP-T , RPTP-rho , receptor protein tyrosine phosphatase , receptor-type tyrosine-protein phosphatase T , receptor-type tyrosine-protein phosphatase rho , RPTPmam4 , mRPTPrho , receptor protein tyrosine phosphatase-rho

GENE ID SPECIES
11122 Homo sapiens
19281 Mus musculus
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