anti-Secretoglobin, Family 1A, Member 1 (Uteroglobin) (SCGB1A1) Anticorps

SCGB1A1 encodes a member of the secretoglobin family of small secreted proteins. De plus, nous expédions SCGB1A1 Protéines (32) et SCGB1A1 Kits (30) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
SCGB1A1 7356 P11684
SCGB1A1 22287 Q06318
SCGB1A1 25575 P17559
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Top anti-SCGB1A1 Anticorps sur

Showing 10 out of 156 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Lapin Inconjugué IHC, WB Immunohistochemistry with Lung, respiratory epithelium tissue at an antibody concentration of 5µg/ml using anti-SCGB1A1 antibody (ARP41524_P050) Host:  Rabbit  Target Name:  SCGB1A1  Sample Type:  Human Thyroid  Antibody Dilution:  2.0 ug/ml 100 μL 2 to 3 Days
Humain Souris Inconjugué FACS, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 3: Western blot analysis using SCGB1A1 mAb against human SCGB1A1 recombinant protein. (Expected MW is 33.4 kDa) 0.1 mg 3 to 4 Days
Humain Souris Inconjugué ELISA, FACS 100 μg 11 to 14 Days
Humain Lapin Inconjugué IHC, IHC (p), WB Anti-SCGB1A1 / Uteroglobin antibody IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959025 concentration 5 ug/ml. Anti-SCGB1A1 / Uteroglobin antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconj ... 100 μL 11 to 14 Days
Souris Lapin Inconjugué IF (p), IHC (p) Formalin-fixed and paraffin embedded rat lung labeled with Anti-CC16/CCSP Polyclonal Antibody, Unconjugated (ABIN687262) followed by conjugation to the secondary antibody and DAB staining Antigen: 0.2ug/100ul, Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000, Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000, TMB staining, Read the data in MicroplateReader by 450nm 100 μL 3 to 7 Days
Humain Lapin Inconjugué ELISA, IHC, WB Western blot analysis of extracts of mouse lung , using SCGB1A1 antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6276844 at 1/100 staining Human Melanoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL 11 to 12 Days
Humain Lapin Inconjugué ELISA, IHC, IHC (p), WB Human Lung, Airway: Formalin-Fixed, Paraffin-Embedded (FFPE) 100 μg 11 to 14 Days
Humain Lapin Inconjugué ICC, IHC, WB 100 μL 15 to 18 Days
Souris Lapin Inconjugué ICC, IHC, WB 100 μL 15 to 18 Days
Rat Lapin Inconjugué ICC, IHC, WB 100 μL 15 to 18 Days

anti-SCGB1A1 Anticorps mieux référencés

  1. Human Monoclonal SCGB1A1 Primary Antibody pour FACS, ELISA - ABIN1098131 : Paantjens, Otten, van Ginkel, van Kessel, van den Bosch, Kwakkel-van Erp, van de Graaf: Clara cell secretory protein and surfactant protein-D do not predict bronchiolitis obliterans syndrome after lung transplantation. dans Transplantation 2010 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal SCGB1A1 Primary Antibody pour IA, IHC (fro) - ABIN2192038 : Geerts, Jorens, Willems, De Ley, Slegers: Natural inhibitors of neutrophil function in acute respiratory distress syndrome. dans Critical care medicine 2001 (PubMed)

  3. Human Monoclonal SCGB1A1 Primary Antibody pour ELISA - ABIN563338 : Archer, Abi-Rizk, Desloire, Dolmazon, Gineys, Guiguen, Cottin, Mornex, Leroux: Lung progenitors from lambs can differentiate into specialized alveolar or bronchiolar epithelial cells. dans BMC veterinary research 2014 (PubMed)

  4. Mouse (Murine) Polyclonal SCGB1A1 Primary Antibody pour IF (p), IHC (p) - ABIN687262 : Mori, Sasaki, Makabe, Yoshinari, Yajima: The genes Scgb1a1, Lpo and Gbp2 characteristically expressed in peri-implant epithelium of rats. dans Clinical oral implants research 2015 (PubMed)

Plus d’anticorps contre SCGB1A1 partenaires d’interaction

Human Secretoglobin, Family 1A, Member 1 (Uteroglobin) (SCGB1A1) interaction partners

  1. CC16 is a homodimeric pneumoprotein encoded by the SCGB1A1 gene and, although produced predominantly by club cells and nonciliated epithelial cells in the distal airways, it is easily detectable in the circulation.

  2. Long-term exposure to silica dust may lead to a decrease in serum CC16 levels

  3. Long-term exposure to silica dust may result in a reduction in CC16 levels in serum; additionally, CC16 can be used as a blood serum biomarker for higher accuracy in the diagnosis of silicosis.

  4. Low serum CC16 was associated with smoking-related decline in lung function, demonstrated the first time in a Chinese cohort. The data also lend support to the putative role of CC16 in protection against smoking-related bronchial epithelial damage.

  5. Concentrations of CC-16 and IL-6 were higher in grain dust exposed workers

  6. Donor CCSP G38A polymorphism is associated with a decreased risk of severe primary graft dysfunction after lung transplantation in a French cohort study

  7. In dramatic expansion of an SCGB1A1+ airway cell population.

  8. Serum CC-16 levels were significantly lower in patients with Asthma and COPD overlap and in those with severe obstruction with high reversibility and frequent exacerbations. Decreased serum CC-16 could possibly distinguish patients with Asthma and COPD overlap or frequent exacerbators in chronic inflammatory airway diseases.

  9. The uteroglobin gene may play an important role in the development of childhood idiopathic nephrotic syndrome, and the AA genotype of UG gene G38A polymorphism was found more frequently in those children

  10. There was no evidence that serum CC16 levels played a role in recurrent wheezing and a positive asthma predictive index in pre-school children

  11. Data suggest that the increase in plasma club cell protein (CC16) CC16 following inhaled allergen as a biomarker of epithelial dysfunction.

  12. We propose that increased CC-16 levels is a marker of lung inflammatory response that associated with ventilatory insufficiency are related to impending respiratory failure, not fully predicted by conventional respiratory tests

  13. Studied serum CC16 levels in The serum CC16 levels in Acute respiratory distress syndrome (ARDS) and non-ARDS patients; found CC16 to be were significantly higher in ARDS patients than that in non-ARDS patients.

  14. Studied serum CC16 levels in relation to atopy and previously manifested low respiratory tract diseases. Found low serum CC16 is associated with previously expressed pneumonia and chronic wheezing in atopic children.

  15. Our data suggest that rCC16 suppresses LPS-mediated inflammatory mediator TNF-alpha, IL-6, and IL-8 production by inactivating NF-kappaB and p38 MAPK but not AP-1 in RAW264.7 cells.

  16. There were associations between urinary CC16 and arsenic concentration in soil, water, house dust, and dust loading. In multiple analyses, only the concentration of arsenic in soil was associated with urinary CC16 levels after accounting for other factors.

  17. findings demonstrate that CC16 is upregulated in IPF patients suggesting that may participate in its pathogenesis.

  18. The G38A CCSP gene polymorphism may alter either the production of the protein and/or its activity in chronic obstructive pulmonary disease.

  19. CC16 levels differed among idiopathic pulmonary fibrosis, pulmonary sarcoidosis and chronic pulmonary obstructive disease.

  20. Lung-specific (CC-16) and novel (RelB) biomarkers are associated with systemic cardiovascular changes over time. CC-16 can predict subsequent exacerbations in subjects with severe COPD and may be an important biomarker of pulmonary and systemic stress in COPD.

Horse (Equine) Secretoglobin, Family 1A, Member 1 (Uteroglobin) (SCGB1A1) interaction partners

  1. role of Secretoglobin 1A1 and 1A1A in neutrophil reactive oxygen species production, phagocytosis and extracellular trap formation [secretoglobin 1A1][secretoglobi 1A1A]

Rabbit Secretoglobin, Family 1A, Member 1 (Uteroglobin) (SCGB1A1) interaction partners

  1. In the oviduct tissue, a decrease in the level of SCGB1A1 mRNA expression was observed from 144 h post-ovulation.In the endometrium a significant decline in the level of SCGB1A1 mRNA expression from 16 to 144 h post-ovulation induction was observed.

Mouse (Murine) Secretoglobin, Family 1A, Member 1 (Uteroglobin) (SCGB1A1) interaction partners

  1. In the mouse fulminant hepatitis (FH) model revealed that CC10 protects against MHV-3-induced FH via suppression of Fgl2 expression in macrophages. In vitro, CC10 was found to significantly inhibit the expression of Fgl2 in MHV-3-infected mouse peritoneal macrophages. Such effects may be mediated by the transcription factor HBP1.

  2. the present results demonstrate that rCC16 has therapeutic effects on COPD by downregulating proinflammatory factors via the NFkappaB pathway.

  3. This study extends the function of the Scgb1a1-expressing epithelial cell population as a major mediator of the antiviral response. It

  4. Chronic P. aeruginosa inflammation resulted in chronic bronchitis and emphysematous changes in CCSP-deficient mice.

  5. CC16 protects lungs from cigarette smoke (CS)-induced injury by reducing lung NF-kappaB activation. CS-induced airway CC16 deficiency increases CS-induced pulmonary inflammation and injury and likely contributes to the pathogenesis of COPD.

  6. Depletion of bone marrow CCSP-expressing cells delays airway regeneration.

  7. Suggest role for Scgb1a1(+) cells in the generation of p63(+) cells in the damaged lung parenchyma.

  8. Serum CC-16 is associated with disease progression in chronic obstructive pulmonary disease (COPD). However, the absence of CC-16 does not appear to modify the risk of cigarette-related COPD in mice.

  9. These findings indicate that CCSP has a regulatory role in obliterative bronchiolitis.

  10. the role of clara cells and clara cell secretory protein in lung radiation injury exacerbated by viral infection

  11. AAV2/9-CC10 vector virus guaranteed sufficient CC10 expression and had an anti-inflammatory effect in asthmatic mice.

  12. Claudin-3 and Clara cell 10 kDa protein were identified as possible markers of early tobacco smoke-induced epithelial injury along alveolar ducts.

  13. Scgb1a1-expressing cells, most likely Clara cells, are a major cell type that gives rise to alveolar type I and II cells during the regeneration of alveolar epithelia in response to severe pulmonary damage in mice.

  14. These results indicate that CC10 gene transfer may inhibit airway inflammation through suppressing the activation of NF-kappaB.

  15. Clara cell secretory protein expression is elevtaed in lungs after long-term n-hexane inhalation exposure.

  16. CCSP promoter has a role in alveolar development

  17. The expression of CC10 is downregulated in sinonasal mucosa in bacterial chronic rhinosinusitis.

  18. Expression of SCGB1A1 mRNA was not decreased in vivo in the absence of C/EBPs.

  19. In the context of allergic airway responses, CC10 can inhibit OPN expression and suppress the Th2-promoting function of OPN, resulting in CC10's inhibitory biological effects.

  20. The differential expression of mRNA by both airway level and lung region was determined for Clara cell secretory protein.

SCGB1A1 profil antigène

Profil protéine

This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma.

Gene names and symbols associated with SCGB1A1

  • secretoglobin family 1A member 1 (SCGB1A1) anticorps
  • secretoglobin, family 1A, member 1 (uteroglobin) (SCGB1A1) anticorps
  • secretoglobin, family 1A, member 1 (uteroglobin) (Scgb1a1) anticorps
  • secretoglobin family 1A member 1 (Scgb1a1) anticorps
  • CC10 anticorps
  • CC16 anticorps
  • CCPBP anticorps
  • CCSP anticorps
  • PCB-BP anticorps
  • PCBB anticorps
  • SCGB1A1 anticorps
  • UG anticorps
  • Ugb anticorps
  • UGL anticorps
  • UP-1 anticorps
  • UP1 anticorps
  • Utg anticorps

Protein level used designations for SCGB1A1

blastokinin , clara cell phospholipid-binding protein , clara cells 10 kDa secretory protein , urinary protein 1 , urine protein 1 , uteroglobin , secretoglobin family 1A member 1 , Blastokinin , CCPBP , PCB-binding protein , clara cell 17 kDa protein , clara cell secretory protein , Uteroglobin (Clara cell secretory protein) , secretoglobin, family 1A, member 1 (uteroglobin)

7356 Homo sapiens
767867 Bos taurus
100033916 Equus caballus
100009053 Oryctolagus cuniculus
22287 Mus musculus
25575 Rattus norvegicus
466634 Pan troglodytes
476060 Canis lupus familiaris
100431098 Ovis aries
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