anti-Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 7 (SLC12A7) Anticorps

Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. De plus, nous expédions SLC12A7 Protéines (7) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
SLC12A7 10723 Q9Y666
SLC12A7 308069 Q5RK27
SLC12A7 20499 Q9WVL3
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Top anti-SLC12A7 Anticorps sur anticorps-enligne.fr

Showing 10 out of 67 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Chèvre Inconjugué ELISA   100 μg 6 to 7 Days
$291.53
Détails
Humain Lapin Inconjugué WB WB Image Sample(30 μg of whole cell lysate) A:H1299 7.5% SDS PAGE antibody diluted at 1:500 100 μL 3 to 4 Days
$466.18
Détails
Humain Lapin Inconjugué IHC (p), WB Western blot analysis in HepG2 cell line lysates (35ug/lane). SLC12A7 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL 2 to 3 Days
$515.63
Détails
Hamster Chèvre Inconjugué ELISA   100 μg 11 to 14 Days
$507.83
Détails
Humain Lapin Inconjugué WB   100 μL 11 to 14 Days
$537.17
Détails
Humain Lapin Inconjugué ELISA, WB   100 μg 11 to 14 Days
$1,123.83
Détails
Souris Lapin Inconjugué ELISA, WB   100 μg 11 to 14 Days
$1,123.83
Détails
Humain Lapin Inconjugué WB Western blot analysis of extracts of various cell lines, using SLC12A7 antibody. 200 μL 12 to 14 Days
$438.90
Détails
Souris Lapin Inconjugué ELISA, WB   100 μL 11 to 14 Days
$1,079.83
Détails
Souris Lapin Inconjugué IF, IHC, ELISA, WB   100 μL 11 to 14 Days
$551.83
Détails

anti-SLC12A7 Anticorps mieux référencés

  1. Human Polyclonal SLC12A7 Primary Antibody pour ELISA - ABIN449541 : Simard, Bergeron, Frenette-Cotton, Carpentier, Pelchat, Caron, Isenring: Homooligomeric and heterooligomeric associations between K+-Cl- cotransporter isoforms and between K+-Cl- and Na+-K+-Cl- cotransporters. dans The Journal of biological chemistry 2007 (PubMed)

  2. Human Polyclonal SLC12A7 Primary Antibody pour IHC, IHC (p) - ABIN4328467 : Brown, Murtha, Rubinstein, Korah, Carling: SLC12A7 alters adrenocortical carcinoma cell adhesion properties to promote an aggressive invasive behavior. dans Cell communication and signaling : CCS 2019 (PubMed)

Plus d’anticorps contre SLC12A7 partenaires d’interaction

Human Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 7 (SLC12A7) interaction partners

  1. SLC12A7 alters adrenocortical carcinoma cell adhesion properties to promote an aggressive invasive behavior

  2. SLC12A7 gene amplification and overexpression occurs frequently in adrenocortical carcinoma and may play a role in adrenocortical carcinoma tumorigenesis.

  3. The Wnk3 protein isoforms have a similar effect on SLC12 cotransporters. NKCC1/2 and NCC were inhibited, even in hypertonicity, while KCCs were activated, even in isotonic conditions.

  4. KCC3 is the dominant isoform in erythrocytes, with variable expression of KCC1 and KCC4 that could result in modulation of KCC activity

  5. Negative stain transmission electron microscopy and single particle analysis of KCC4 and the aquaporin-1 AQP1 water channel, revealed the expected quaternary structures within homogeneous preparations, and thus correct protein folding and assembly.

  6. analysis of differences in large extracellular loop between the K(+)-Cl(-) cotransporters KCC2 and KCC4

  7. human osteoblasts express functional K-Cl cotransporters in their cell membrane that seem to be able to induce the indirect activation of volume-sensitive Cl- channels by KCl through an increase in the intracellular ions, water influx and cell swelling.

  8. KCC activation by IGF-1 plays an important role in IGF-1 signaling to promote growth and spread of gynecological cancers.

  9. Among patients with early-stage node-negative breast cancer, disease-free survival (DFS) and overall survival (OS) curves were significantly different based on IGF-1 and KCC expression.

  10. KCC4 and H+,K+-ATPase are the main machineries for basal HCl secretion in the apical canalicular membrane of the resting parietal cell. They also may contribute in part to massive acid secretion in the stimulated state.

  11. In the metastatic cancer tissues, KCC4 colocalizes with IGF-I or EGF.

  12. Mice lacking SLC12A7 function suffer from deafness and renal metabolic acidosis. The phenotype suggests a function in inner ear potassium recycling. A function in the proton secreting alpha-intercalating cells of the kidney is shown.

Mouse (Murine) Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 7 (SLC12A7) interaction partners

  1. During cell swelling PP1alpha and PP1gamma1 are involved in KCC4 regulation by WNK4, but that the kinase acts upon these phosphatases to inhibit their activity.

  2. Data are consistent with a role for KCC4 in salt reabsorption of the thick ascending loop of Henle's loop and acid secretion of the collecting duct.

  3. We propose that glycosylation is essential for the surface expression, stabilization, and bioactivity of KCC4

  4. KCC3 is the dominant isoform in erythrocytes, with variable expression of KCC1 and KCC4 that could result in modulation of KCC activity

  5. Mice lacking SLC12A7 function suffer from deafness and renal metabolic acidosis. The phenotype suggests a function in inner ear potassium recycling. A function in the proton secreting alpha-intercalating cells of the kidney is shown.

  6. Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1) with the cotransporters KCC3, NKCC1, and NKCC2 but not KCC1 and KCC4

  7. all of the CCCs examined (NKCC1, NKCC2, KCC1, KCC3, and KCC4) can promote NH4(+) translocation, presumably through binding of the ion at the K(+) site

  8. KCC4 and H+,K+-ATPase are the main machineries for basal HCl secretion in the apical canalicular membrane of the resting parietal cell. They also may contribute in part to massive acid secretion in the stimulated state.

SLC12A7 profil antigène

Profil protéine

Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification (By similarity).

Gene names and symbols associated with SLC12A7

  • solute carrier family 12 (potassium/chloride transporters), member 7 (SLC12A7) anticorps
  • solute carrier family 12 member 7 (SLC12A7) anticorps
  • solute carrier family 12 member 7 (Slc12a7) anticorps
  • solute carrier family 12, member 7 (Slc12a7) anticorps
  • AA408796 anticorps
  • D13Ertd261e anticorps
  • Kcc4 anticorps
  • Slc12a5 anticorps
  • SLC12A7 anticorps

Protein level used designations for SLC12A7

solute carrier family 12 (potassium/chloride transporters), member 7 , K-Cl cotransporter 4 , electroneutral potassium-chloride cotransporter 4 , potassium/chloride transporter KCC4 , solute carrier family 12 member 7 , K-Cl cotransporter KCC4 , furosemide-sensitive KCl cotransporter 4 , potassium-chloride cotransporter

GENE ID SPECIES
528038 Bos taurus
709581 Macaca mulatta
10723 Homo sapiens
308069 Rattus norvegicus
100008847 Oryctolagus cuniculus
20499 Mus musculus
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