TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C, 110kDa Protéines (TAF1C)

Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. De plus, nous expédions TAF1C Anticorps (33) et et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
TAF1C 21341 Q6PDZ2
Rat TAF1C TAF1C 361420 Q6P773
TAF1C 9013 Q15572
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Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,984.89
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,984.89
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails

TAF1C Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Mouse (Murine)

Human ,
,

Plus protéines pour TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C, 110kDa (TAF1C) partenaires d'interaction

Human TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C, 110kDa (TAF1C) interaction partners

  1. hCdc14B (Montrer CDC14B Protéines) promotes reactivation of rDNA transcription by dephosphorylating TAFI110. SIRT1 (Montrer SIRT1 Protéines) becomes transiently enriched in nucleoli at the onset of mitosis. SIRT1 (Montrer SIRT1 Protéines) deacetylates TAFI68 destabilizing SL1 (Montrer MMP3 Protéines) binding to the rDNA promoter

  2. Our results indicate that TAF1C gene harboured not only somatic frameshift mutations but also the mutational ITH, which together might play a role in tumourigenesis of gastric and colorectal cancer.

  3. SL1 (Montrer MMP3 Protéines) directs preinitiation complex formation, functioning in core promoter binding, RNA polymerase I (Montrer POLR1C Protéines) recruitment, and UBF (Montrer UBTF Protéines) stabilization.

  4. PTEN represses RNA Pol I transcription through a novel mechanism that involves disruption of the SL1 (Montrer MMP3 Protéines) complex

Profil protéine TAF1C

Profil protéine

Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with TAF1C

  • TATA-box binding protein associated factor, RNA polymerase I subunit C (TAF1C)
  • TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa (TAF1C)
  • TATA-box binding protein associated factor, RNA polymerase I, C (Taf1c)
  • TATA-box binding protein associated factor, RNA polymerase 1 subunit C (Taf1c)
  • MGC:39976 Protéine
  • mTAFI95 Protéine
  • SL1 Protéine
  • TAF1C Protéine
  • TAFI95 Protéine
  • TAFI110 Protéine

Protein level used designations for TAF1C

TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa , TBP-associated factor 1C , TATA box-binding protein-associated factor RNA polymerase I subunit C-like , RNA polymerase I-specific TBP-associated factor 95 kDa , TATA box binding protein (Tbp)-associated factor, RNA polymerase I, C; transcription factor TAFI95 , TATA box-binding protein-associated factor 1C , TATA box-binding protein-associated factor RNA polymerase I subunit C , TBP-associated factor RNA polymerase I 95 kDa , transcription factor TAFI95 , transcription initiation factor SL1/TIF-IB subunit C , TATA box-binding protein-associated factor, RNA polymerase I, subunit C , RNA polymerase I-specific TBP-associated factor 110 kDa , SL1, 110kD subunit , transcription factor SL1

GENE ID SPECIES
454279 Pan troglodytes
772287 Gallus gallus
100396141 Callithrix jacchus
100461311 Pongo abelii
100475343 Ailuropoda melanoleuca
100516196 Sus scrofa
21341 Mus musculus
361420 Rattus norvegicus
9013 Homo sapiens
609622 Canis lupus familiaris
509238 Bos taurus
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