anti-Tumor Protein P53 Binding Protein 2 (TP53BP2) Anticorps

TP53BP2 encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. De plus, nous expédions Tumor Protein P53 Binding Protein 2 Kits (4) et Tumor Protein P53 Binding Protein 2 Protéines (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
TP53BP2 7159 Q13625
TP53BP2 209456 Q8CG79
TP53BP2 305025  
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Top anti-Tumor Protein P53 Binding Protein 2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 77 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-TP53BP2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  Human Thymus 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué EIA, WB TP53BP2 Antibody (N-term) western blot analysis in T47D cell line lysates (35 µg/lane). This demonstrates the TP53BP2 antibody detected the TP53BP2 protein (arrow). 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Humain Lapin Inconjugué WB WB Image Sample (30 ug of whole cell lysate) A: NT2D1 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Connectez-vous pour afficher 1 to 2 Days
$358.60
Détails
Chien Lapin Inconjugué EIA, WB   0.1 mg Connectez-vous pour afficher 8 to 11 Days
$619.30
Détails
Humain Lapin Inconjugué IHC, ELISA, WB ASPP2 staining in human uterine cancer tissue. Paraffin-embedded human uterine cancer tissue is stained with ASPP2 Antibody used at 1:200 dilution. 0.1 mg Connectez-vous pour afficher 2 to 6 Days
$377.30
Détails
Humain Lapin Inconjugué WB TP53BP2 Antibody (N-term)  western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the TP53BP2 antibody detected the TP53BP2 protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Lapin Inconjugué IP, WB 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$556.31
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: 53BP2 Antibody [ABIN251338] - FFPE section of human prostate adenocarcinoma. Affinity purified rabbit anti-ASPP2 at a dilution of 1:500. 100 μL Connectez-vous pour afficher 7 to 9 Days
$556.31
Détails
Humain Lapin Inconjugué IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse lung labeled with Rabbit Anti-ASPP2/p53BP2 Polyclonal Antibody, Unconjugated (ABIN674394) at 1:200 followed by conjugation to the secondary antibody and DAB staining Lane 1: Mouse spleen lysate Lane 2: Mouse thymus lysate Lane 3: Mouse prostate lysate Lane 4: Mouse intestine lysate probed with Rabbit Anti-ASPP2/p53BP2 Polyclonal Antibody, Unconjugated (ABIN674394) at 1:300 overnight at 4 °C. Followed by conjugation to secondary antibody  at 1:5000 for 90 min at 37 °C. 100 μL Connectez-vous pour afficher 3 to 7 Days
$318.45
Détails
Humain Lapin Inconjugué ELISA, WB 100 μg Connectez-vous pour afficher 7 to 9 Days
$639.83
Détails

TP53BP2 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-Tumor Protein P53 Binding Protein 2 Anticorps mieux référencés

  1. Human Polyclonal TP53BP2 Primary Antibody pour IF (p), IHC (p) - ABIN674394 : Xie, Yang, Chi, Yang, Wang, Xu: Prognostic values of apoptosis-stimulating P53-binding protein 1 and 2 and their relationships with clinical characteristics of esophageal squamous cell carcinoma patients: a retrospective study. dans Chinese journal of cancer 2017 (PubMed)

  2. Human Polyclonal TP53BP2 Primary Antibody pour IHC, ELISA - ABIN1584022 : Matsumoto, Weckbecker, Cory: Antineoplastic effect of the combination of 2,3-dihydro-1H-pyrazole[2,3a]imidazole plus deoxyadenosine/erythro-9-(2-hydroxyl-3-nonyl)adenine in mice with L1210 leukemia cells. dans Cancer communications 1990 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre Tumor Protein P53 Binding Protein 2 partenaires d’interaction

Human Tumor Protein P53 Binding Protein 2 (TP53BP2) interaction partners

  1. These findings identify TP53BP2 as a strong candidate causative gene for central nervous system (CNS) defects in 1q41q42 microdeletion syndrome.

  2. Results showed that protein expression levels of ASPP2 and P53 (Montrer TP53 Anticorps) were significantly higher in esophageal squamous cell carcinoma tissues than in paired noncancerous tissues.

  3. Expression levels of TP53BP2, FBXO28 (Montrer FBXO28 Anticorps), and FAM53A (Montrer Fam53a Anticorps) genes were associated with patient survival specifically in ER-positive, TP53 (Montrer TP53 Anticorps)-mutated tumors.

  4. These data together implicated a critical impact of MiR (Montrer MLXIP Anticorps)-205/ASPP2 on promoting epithelial-mesenchymal transition.

  5. ASPP2 is a key regulator of BECN1 (Montrer BECN1 Anticorps)-dependent autophagy.

  6. ASPP2 suppresses invasion, peritoneal dissemination and TGF-beta1 (Montrer TGFB1 Anticorps)-induced EMT (Montrer ITK Anticorps) by inhibiting Smad7 (Montrer SMAD7 Anticorps) degradation mediated by ITCH in gastric cancer cells.

  7. Our results suggest that Gal-1 and ASPP2 functionally compete in nanocluster for active Ras on the plasma membrane. ASPP2 dominates the biological outcome, thus switching from a Gal-1 supported growth-promoting setting to a senescence inducing and stemness suppressive program in cancer cells. Our results support Ras nanocluster as major integrators of tumour fate decision events.

  8. ASPP2 suppresses p53 (Montrer TP53 Anticorps) target gene transactivation, promoter occupancy, and endogenous p53 (Montrer TP53 Anticorps) target gene expression in response to DNA damage

  9. In this study, in recombinant adenovirus-ASPP2-infected HepG2 cells, ASPP2 overexpression induces amphiregulin (Montrer AREG Anticorps) expression in a p53 (Montrer TP53 Anticorps)-dependent manner

  10. Downregulated expression of ASPP2 is associated with hepatocellular carcinoma.

Zebrafish Tumor Protein P53 Binding Protein 2 (TP53BP2) interaction partners

  1. These findings uncover a novel role of Aspp2 in regulating vertebrate embryonic growth.

Mouse (Murine) Tumor Protein P53 Binding Protein 2 (TP53BP2) interaction partners

  1. These results suggest that ASPP2 plays an important role in p53 (Montrer TP53 Anticorps)-mediated neuronal apoptosis under gp120 (Montrer ITIH4 Anticorps) stress.

  2. These findings identify TP53BP2 as a strong candidate causative gene for central nervous system (CNS) defects in 1q41q42 microdeletion syndrome.

  3. SPP2 dominates the biological outcome, thus switching from a Gal-1 supported growth-promoting setting to a senescence inducing and stemness suppressive program in cancer cells. Our results support Ras nanocluster as major integrators of tumour fate decision events.

  4. ASPP2 may participate in the lipid metabolism of non-alcoholic steatohepatitis and attenuate liver failure.

  5. ASPP2 prevents beta-catenin (Montrer CTNNB1 Anticorps) from transactivating ZEB1 (Montrer ZEB1 Anticorps) directly by forming an ASPP2-beta-catenin (Montrer CTNNB1 Anticorps)-E-cadherin (Montrer CDH1 Anticorps) ternary complex

  6. findings suggest that the identified STAT1 (Montrer STAT1 Anticorps)/ASPP2 pathway may connect tumor suppression and cell polarity to neuroinflammation

  7. our studies demonstrate the role of Siah2 (Montrer SIAH2 Anticorps) in regulation of tight junction integrity and cell polarity under hypoxia, through its regulation of ASPP2 stability.

  8. ASPP2 is a tumor suppressor that suppresses squamous cell carcinoma via inflammatory signaling through NF-kappaB (Montrer NFKB1 Anticorps)-mediated repression of p63 (Montrer CKAP4 Anticorps).

  9. Our study demonstrates a novel role for ASPP1 (Montrer PPP1R13B Anticorps) and ASPP2 in the death of retinal ganglion cells.

  10. regulates epithelial cell polarity in cooperation with PAR-3 (Montrer F2RL2 Anticorps) to form an active PAR (Montrer AFG3L2 Anticorps) complex

Tumor Protein P53 Binding Protein 2 (TP53BP2) profil antigène

Profil protéine

This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with TP53BP2

  • tumor protein p53 binding protein 2 (TP53BP2) anticorps
  • tumor protein p53 binding protein 2 L homeolog (tp53bp2.L) anticorps
  • tumor protein p53 binding protein 2 (tp53bp2) anticorps
  • tumor protein p53 binding protein, 2b (tp53bp2b) anticorps
  • transformation related protein 53 binding protein 2 (Trp53bp2) anticorps
  • tumor protein p53 binding protein, 2 (Tp53bp2) anticorps
  • tumor protein p53 binding protein, 2a (tp53bp2a) anticorps
  • tumor protein p53 binding protein 2 (Tp53bp2) anticorps
  • 53BP2 anticorps
  • AI746547 anticorps
  • ASPP2 anticorps
  • BBP anticorps
  • P53BP2 anticorps
  • PPP1R13A anticorps
  • Tp53bp2 anticorps
  • Trp53bp2 anticorps
  • wu:fa09h08 anticorps
  • wu:fb04e08 anticorps
  • X98550 anticorps
  • zgc:85720 anticorps

Protein level used designations for TP53BP2

BCL2-binding protein , apoptosis-stimulating of p53 protein 2 , apoptosis-stimulating protein of p53, 2 , renal carcinoma antigen NY-REN-51 , tumor suppressor p53-binding protein 2 , tumor protein p53 binding protein, 2 , apoptosis-stimulating of p53 protein 2-like , p53-binding protein 2 , p53BP2 , transformation related protein 53 binding protein 2 , fb04e08

GENE ID SPECIES
7159 Homo sapiens
421329 Gallus gallus
446947 Xenopus laevis
457766 Pan troglodytes
490397 Canis lupus familiaris
514474 Bos taurus
548790 Xenopus (Silurana) tropicalis
568138 Danio rerio
705383 Macaca mulatta
100055278 Equus caballus
100221962 Taeniopygia guttata
100445132 Pongo abelii
100519863 Sus scrofa
209456 Mus musculus
305025 Rattus norvegicus
407983 Danio rerio
100732221 Cavia porcellus
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