anti-Tyrosine Kinase, Non-Receptor, 1 (TNK1) Anticorps

The protein encoded by TNK1 belongs to the tyrosine protein kinase family. De plus, nous expédions TNK1 Kits (5) et TNK1 Protéines (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
TNK1 83813 Q99ML2
TNK1 8711 Q13470
TNK1 303247  
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Top anti-TNK1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 132 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Cobaye Lapin Inconjugué WB Host: RabbitTarget Name: TNK1Antibody Dilution: 1.0ug/mlSample Tissue: RPMI-8226 cell lysate 100 μL 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué IHC, WB Western blot analysis of extracts of L-540 cells, using Phospho-TNK1 (Tyr277) Antibody. ABIN6267199 at 1/100 staining Human thyroid cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL 11 to 12 Days
$390.77
Détails
Humain Souris Inconjugué ELISA, WB 100 μL 11 to 14 Days
$478.50
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB 0.4 mL 6 to 8 Days
$484.00
Détails
Humain Lapin Inconjugué IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse embryo labeled with Anti-Phospho-TNK1(Tyr277) Polyclonal Antibody, Unconjugated (ABIN746513) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL 3 to 7 Days
$339.90
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB Anti-TNK1 antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. This image was taken for the unconjugated form of this ... 100 μL 11 to 14 Days
$727.83
Détails
Humain Lapin Inconjugué IHC (p), WB Western blot analysis of anti-TNK1 pab in Hela cell line lysate. Dilution of anti-TNK1 was 1:100; dilution of secondary antibody (goat anti-rabbit-HRP) was 1:7000. Data and protocol courtesy of Dr. Richard Lu, Partners HealthCare System at Harvard University. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma; HC = hepatocarcinoma. 400 μL 2 to 3 Days
$515.63
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of TNK1 expression in RPMI-8226 cell lysate ,The lane on the left is treated with the antigen-specific peptide. 100 μL 11 to 12 Days
$390.77
Détails
Humain Lapin Inconjugué WB Western blot analysis of TNK1 Antibody in T47D cell line lysates (35ug/lane) 400 μL 2 to 3 Days
$515.63
Détails
Humain Lapin Inconjugué WB   100 μL 11 to 14 Days
$859.83
Détails

anti-TNK1 Anticorps mieux référencés

  1. Human Polyclonal TNK1 Primary Antibody pour IHC (p), ELISA - ABIN544399 : Jhiang: The RET proto-oncogene in human cancers. dans Oncogene 2000 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal TNK1 Primary Antibody pour ELISA, WB - ABIN1724711 : Hoare, Hoare, Smith, Kalmaz, Small, Stratford May: Kos1, a nonreceptor tyrosine kinase that suppresses Ras signaling. dans Oncogene 2003 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre TNK1 partenaires d’interaction

Mouse (Murine) Tyrosine Kinase, Non-Receptor, 1 (TNK1) interaction partners

  1. TNK1 was found to be deregulated in the gut in murine and porcine trauma models and human inflammatory bowel disease. Thus, TNK1 might be a target during MODS to prevent damage in several organs, notably the gut.

  2. The activated TNK1 potentiates JAK-STAT signaling through dual phosphorylation of STAT1 at tyrosine 701 and serine 727 amino acid positions.

  3. data support a negative regulatory role for Kos1 in regulating the Ras-Raf1-MAPK growth pathway by a mechanism that requires its autotyrosine kinase activity

  4. Tnk1/Kos1 is a tumor suppressor that functions to down-regulate Ras activity

  5. cellular stress reverses the repression of Tnk1/Kos1 and induces its expression through increased high affinity interactions between nuclear proteins Sp1, Sp3, AP2 and MED1 for the m-Tnk1 promoter

Human Tyrosine Kinase, Non-Receptor, 1 (TNK1) interaction partners

  1. TNK1 was found to be deregulated in the gut in murine and porcine trauma models and human inflammatory bowel disease. Thus, TNK1 might be a target during MODS to prevent damage in several organs, notably the gut.

  2. the Single nucleotide polymorphisms rs11136000 of CLU, rs541458 of PICALM, and rs1554948 of TNK1 according to the three age groups 50-65 years (group 1), 66-80 years (group 2), and 80+ years (group 3) in 569 older subjects without cognitive impairment (NoCI) and 520 Alzheimer's disease (AD) patients, were studied.

  3. The activated TNK1 potentiates JAK-STAT signaling through dual phosphorylation of STAT1 at tyrosine 701 and serine 727 amino acid positions.

  4. The application of functional genomics by using high-throughput-RNAi screens has allowed us to identify TNK1 as a growth-associated kinase in pancreatic cancer cells.

  5. Activated Tnk1 kinase is associated with Hodgkin's lymphoma.

  6. TNK1 therefore acts as a novel molecular switch that can determine the properties of TNFalpha signaling and therefore cell death.

TNK1 profil antigène

Profil protéine

The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with TNK1

  • tyrosine kinase non receptor 1 (TNK1) anticorps
  • tyrosine kinase, non-receptor, 1 (Tnk1) anticorps
  • tyrosine kinase non receptor 1 (Tnk1) anticorps
  • Ack-like anticorps
  • Kos1 anticorps
  • Tnk1a anticorps
  • Tnk1b anticorps

Protein level used designations for TNK1

kinase of embryonic stem cells , non-receptor tyrosine kinase , non-receptor tyrosine-protein kinase TNK1 , CD38 negative kinase 1

GENE ID SPECIES
100061776 Equus caballus
83813 Mus musculus
8711 Homo sapiens
303247 Rattus norvegicus
510356 Bos taurus
489470 Canis lupus familiaris
100735628 Cavia porcellus
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