Profil protéine

The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with TNK1

• tyrosine kinase non receptor 1 (TNK1) anticorps
• tyrosine kinase, non-receptor, 1 (Tnk1) anticorps
• tyrosine kinase non receptor 1 (Tnk1) anticorps

• Ack-like anticorps
• Kos1 anticorps
• Tnk1a anticorps
• Tnk1b anticorps

Protein level used designations for TNK1

kinase of embryonic stem cells , non-receptor tyrosine kinase , non-receptor tyrosine-protein kinase TNK1 , CD38 negative kinase 1