Zinc Finger, DHHC-Type Containing 13 Protéines (ZDHHC13)

Palmitoyltransferase for HD and GAD2 (By similarity). De plus, nous expédions ZDHHC13 Anticorps (53) et et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
Souris ZDHHC13 ZDHHC13 243983 Q9CWU2
ZDHHC13 54503 Q8IUH4
Rat ZDHHC13 ZDHHC13 365252  
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Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Connectez-vous pour afficher 50 to 55 Days
$7,493.38
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
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ZDHHC13 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human ,
,

Plus protéines pour Zinc Finger, DHHC-Type Containing 13 (ZDHHC13) partenaires d'interaction

Mouse (Murine) Zinc Finger, DHHC-Type Containing 13 (ZDHHC13) interaction partners

  1. The loss of ZDDHC13 in skin, impairs the multiple barrier functions and leads to a dermatitis lesion in response to microbial encounters.

  2. Homozygous Zdhhc13luc/Zdhhc13luc mice developed generalized hypotrichosis, associated with abnormal hair cycle, epidermal and sebaceous gland hyperplasia, hyperkeratosis, and increased epidermal thickness

  3. Data show that the ankyrin repeat (AR) domains of S-acyltransferases zDHHC17 and zDHHC13 recognize peptide sequence in several unrelated proteins.

  4. Zdhhc13 regulates Smad6 during BMP-dependent signaling and early lineage decisions in an in vitro cell model.

  5. Loss of Hip14 and Hip14l leads to early embryonic lethality at day embryonic day 10-11 due to failed chorioallantoic fusion.

  6. Zdhhc13 is a novel regulator of postnatal skeletal development and bone mass acquisition.

  7. Hip14l-deficient mice develop adult-onset, neuropathological deficits characteristic of Huntington disease.

  8. A second gene trap allele of Zdhhc13 has the same phenotypes, suggesting that this is a loss of function allele.

  9. huntingtin interacting protein genes, HIP14 and HIP14L, encode Mg2+ transport proteins that are regulated by their innate palmitoyl acyltransferases thus fulfilling the characteristics of "chanzymes."

Human Zinc Finger, DHHC-Type Containing 13 (ZDHHC13) interaction partners

  1. this is the first study to demonstrate that defects in ZDHHC13, a PAT, leads to phenotypes in mice, including non-thyroidal hypermetabolism, mitochondrial dysfunction, and abnormal lipid metabolism.

  2. This suggests that altered HIP14-HTT and HIP14L-HTT interactions in the presence of the HD mutation reduces palmitoylation and promotes mislocalization of HTT and other HIP14/HIP14L substrates

  3. Data show that deletion of huntingtin protein (HTT) amino acids 1-427 abolishes the interaction of HTT with palmitoyl acyltransferases huntingtin interacting protein 14 (HIP14) and huntingtin interacting protein 14-like (HIP14L).

  4. huntingtin interacting protein genes, HIP14 and HIP14L, encode Mg2+ transport proteins that are regulated by their innate palmitoyl acyltransferases thus fulfilling the characteristics of "chanzymes."

Profil protéine ZDHHC13

Profil protéine

Palmitoyltransferase for HD and GAD2 (By similarity). Mediates Mg(2+) transport (By similarity).

Gene names and symbols associated with ZDHHC13

  • zinc finger DHHC-type containing 13 (ZDHHC13)
  • zinc finger, DHHC domain containing 13 (Zdhhc13)
  • zinc finger, DHHC-type containing 13 (zdhhc13)
  • zinc finger, DHHC-type containing 13 (Zdhhc13)
  • 2410004E01Rik Protéine
  • C530010M18 Protéine
  • HIP3RP Protéine
  • HIP14L Protéine
  • kojak Protéine
  • skc4 Protéine
  • wu:fb06e01 Protéine
  • wu:fc39g10 Protéine
  • wu:fi22e09 Protéine
  • ZDHHC13 Protéine
  • zgc:101690 Protéine

Protein level used designations for ZDHHC13

zinc finger, DHHC-type containing 13 , DHHC-13 , HIP14-related protein , huntingtin-interacting protein 14-related protein , palmitoyltransferase ZDHHC13 , probable palmitoyltransferase ZDHHC13 , zinc finger DHHC domain-containing protein 13 , fi22e09 , huntingtin interacting protein HIP3RP , huntingtin-interacting protein HIP3RP , putative MAPK-activating protein PM03 , putative NF-kappa-B-activating protein 209 , zinc finger, DHHC domain containing 13 , Probable palmitoyltransferase ZDHHC13

GENE ID SPECIES
451071 Pan troglodytes
613004 Canis lupus familiaris
100071954 Equus caballus
243983 Mus musculus
494107 Danio rerio
422980 Gallus gallus
54503 Homo sapiens
514176 Bos taurus
365252 Rattus norvegicus
100174171 Pongo abelii
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