TNNI3 anticorps

N° du produit ABIN1045363

Détail du produit anti-TNNI3 anticorps

Antigène: TNNI3 (Cardiac Troponin I (TNNI3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TNNI3 est non-conjugé

Application: ELISA

Specificité: Reacts equally with free cardiac troponin I and cardiac troponin I forming complexes with other troponin components. Not affected by heparin, phosphorylation and oxidation.

Réactivité croisée: Humain

Réactivité croisée (Details): No cross-reactivity with skeletal muscle troponin I.

Purification: Protein G purified

Pureté: > 95 %

Immunogène: Recombinant Human Cardiac Troponin I protein

Clone: 11D2E10

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Other species are not tested. Please decide the specificity by homology

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Références pour anticorps anti-TNNI3 (ABIN1045363)

Stein, Janjua, Matta, Pathak, Jaweesh, Alrifai, Chughtai: "Prognosis based on creatine kinase isoenzyme MB, cardiac troponin I, and right ventricular size in stable patients with acute pulmonary embolism." dans: The American journal of cardiology, Vol. 107, Issue 5, pp. 774-7, (2011) (PubMed).

Goel, Beith: "Troponin I as a predictor for trastuzumab-related cardiotoxicity: current data do not provide mechanistic insights or allow for incorporation into clinical practice." dans: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 29, Issue 7, pp. e175-6, (2011) (PubMed).

Xue, Clopton, Peacock, Maisel: "Serial changes in high-sensitive troponin I predict outcome in patients with decompensated heart failure." dans: European journal of heart failure, Vol. 13, Issue 1, pp. 37-42, (2010) (PubMed).

Paparella, Scrascia, Paramythiotis, Guida, Magari, Malvindi, Favale, de Luca Tupputi Schinosa: "Preoperative cardiac troponin I to assess midterm risks of coronary bypass grafting operations in patients with recent myocardial infarction." dans: The Annals of thoracic surgery, Vol. 89, Issue 3, pp. 696-702, (2010) (PubMed).

John, Woodward, Wang, Yan, Fisher, Kinasewitz, Heiselman: "Troponin-I as a prognosticator of mortality in severe sepsis patients." dans: Journal of critical care, Vol. 25, Issue 2, pp. 270-5, (2010) (PubMed).

van Geene, van Swieten, Noyez: "Cardiac troponin I levels after cardiac surgery as predictor for in-hospital mortality." dans: Interactive cardiovascular and thoracic surgery, Vol. 10, Issue 3, pp. 413-6, (2010) (PubMed).

Napan, Kashinath, Kadri, Orig, Khadra: "Prognostic significance of preprocedural troponin-I in patients with non-ST elevation acute coronary syndromes undergoing percutaneous coronary intervention." dans: Coronary artery disease, Vol. 21, Issue 5, pp. 261-5, (2010) (PubMed).

Bonaca, Scirica, Sabatine, Dalby, Spinar, Murphy, Jarolim, Braunwald, Morrow: "Prospective evaluation of the prognostic implications of improved assay performance with a sensitive assay for cardiac troponin I." dans: Journal of the American College of Cardiology, Vol. 55, Issue 19, pp. 2118-24, (2010) (PubMed).

Tsutamoto, Kawahara, Nishiyama, Yamaji, Fujii, Yamamoto, Horie: "Prognostic role of highly sensitive cardiac troponin I in patients with systolic heart failure." dans: American heart journal, Vol. 159, Issue 1, pp. 63-7, (2010) (PubMed).

Oshima, Kunimoto, Takahashi, Mohara, Takeyoshi, Hinohara, Okawa, Saito: "Postoperative cardiac troponin I (cTnI) level and its prognostic value for patients undergoing mitral valve surgery." dans: International heart journal, Vol. 51, Issue 3, pp. 166-9, (2010) (PubMed).

Zahid, Good, Singla, Sonel: "Clinical significance of borderline elevated troponin I levels across different assays in patients with suspected acute coronary syndrome." dans: The American journal of cardiology, Vol. 104, Issue 2, pp. 164-8, (2009) (PubMed).

Fruchter, Yigla: "Cardiac troponin-I predicts long-term mortality in chronic obstructive pulmonary disease." dans: COPD, Vol. 6, Issue 3, pp. 155-61, (2009) (PubMed).

Alonso Martínez, Annicchérico Sánchez, Urbieta Echezarreta, García Sanchotena, Ezcurra Ibáñez, Lasa Inchausti: "[Clinical usefulness of troponin I in acute pulmonary embolism]." dans: Medicina clínica, Vol. 133, Issue 6, pp. 201-5, (2009) (PubMed).

Apple: "Tissue specificity of cardiac troponin I, cardiac troponin T and creatine kinase-MB." dans: Clinica chimica acta; international journal of clinical chemistry, Vol. 284, Issue 2, pp. 151-9, (1999) (PubMed).

Détails sur TNNI3

Antigène: TNNI3 (Cardiac Troponin I (TNNI3))

Autre désignation: TNNI3 (TNNI3 Produits)

Synonymes: anticorps CMD1FF, anticorps CMD2A, anticorps CMH7, anticorps RCM1, anticorps TNNC1, anticorps cTnI, anticorps CMD1Z, anticorps CMH13, anticorps TN-C, anticorps TNC, anticorps TNNC, anticorps Tn1, anticorps TnIc, anticorps ctnIc, anticorps XTnIc, anticorps c-troponin, anticorps cTNT, anticorps cmh7, anticorps ctni, anticorps tnnc1, anticorps TNNI3, anticorps TnI, anticorps cTNI, anticorps AI874626, anticorps TnC, anticorps cTnC, anticorps tncc, anticorps Tncc, anticorps troponin I3, cardiac type, anticorps troponin C1, slow skeletal and cardiac type, anticorps troponin I, cardiac 3, anticorps troponin I type 3 (cardiac), anticorps troponin I3, cardiac type S homeolog, anticorps troponin I3, cardiac type L homeolog, anticorps cardiac troponin I, anticorps troponin C, cardiac/slow skeletal, anticorps TNNI3, anticorps TNNC1, anticorps Tnni3, anticorps tnni3.S, anticorps tnni3.L, anticorps tnni3, anticorps LOC100462680, anticorps Tnnc1

Sujet:

Background: Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium.

Aliases: CTnI

UniProt: P19429