BATF anticorps (N-Term)

N° du produit ABIN1077388

Détail du produit anti-BATF anticorps

Antigène: BATF (Basic Leucine Zipper ATF-like Transcription Factor (BATF))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BATF est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Specificité: Multiple isoforms of BATF are known to exist. Despite its predicted molecular weight, BATF often migrates at a higher than expected molecular weight.

Purification: Affinity chromatography purified via peptide column

Immunogène: BATF antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BATF.

Isotype: IgG

Information d'application

Indications d'application: BATF antibody can be used for detection of BATF by Western blot at 0.5 μg/mL. For immunofluorescence start at 20 μg/mL.

Commentaires:

(NT) B-cell activating transcription factor

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C/-20 °C

Stockage commentaire: BATF antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Date de péremption: 12 months

Détails sur BATF

Antigène: BATF (Basic Leucine Zipper ATF-like Transcription Factor (BATF))

Autre désignation: BATF (BATF Produits)

Synonymes: anticorps B-ATF, anticorps si:ch211-153j24.4, anticorps BATF1, anticorps SFA-2, anticorps SFA2, anticorps basic leucine zipper transcription factor, ATF-like, anticorps basic leucine zipper ATF-like transcription factor, anticorps batf, anticorps BATF, anticorps Batf

Sujet: BATF is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events and blocks cellular transformation by Ras and Fos. BATF also is required for the differentiation of IL-17-producing T helper (TH17) cells, a CD4+ subset of T cells that coordinates the inflammatory response in host defense. In both T cells and B cells, BATF is required for the appropriate regulation of the class-switch recombination.
Synonyms: B-cell activating transcription factor, BATF1, basic leucine zipper transcriptional factor ATF-like, SF-HT-activated gene 2 protein, SFA-2, SFA2

Poids moléculaire: 14 kDa

ID gène: 10538

NCBI Accession: NP_006390