PANX1 anticorps (N-Term)

N° du produit ABIN1077400

Détail du produit anti-PANX1 anticorps

Antigène: PANX1 (Pannexin 1 (PANX1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PANX1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificité: Two transcript variants encoding different isoforms have been found for this gene.

Purification: Affinity chromatography purified via peptide column

Immunogène: Rabbit polyclonal PANX1 antibody was raised against a 17 amino acid peptide near the amino terminus of human PANX1.

Isotype: IgG

Information d'application

Indications d'application: PANX1 antibody can be used for detection of PANX1 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.

Commentaires:

(NT) Pannexin 1

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C

Stockage commentaire: PANX1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Date de péremption: 12 months

Détails sur PANX1

Antigène: PANX1 (Pannexin 1 (PANX1))

Autre désignation: PANX1 (PANX1 Produits)

Synonymes: anticorps panx1, anticorps zgc:55631, anticorps PANX1, anticorps px1, anticorps mrs1, anticorps pannexin1, anticorps Pannexin-1, anticorps MRS1, anticorps PX1, anticorps UNQ2529, anticorps AI847747, anticorps pannexin 1a, anticorps pannexin 1, anticorps Pannexin 1, anticorps panx1a, anticorps PANX1, anticorps panx1, anticorps Panx1

Sujet: The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.
Synonyms: Pannexin 1, Pannexin-1, PX1, MRS1, UNQ2529, UNQ2529/PRO6028

Poids moléculaire: 47 kDa

ID gène: 24145

NCBI Accession: NP_056183