BCL3 anticorps (C-Term)

N° du produit ABIN1077425

Détail du produit anti-BCL3 anticorps

Antigène: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCL3 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogène: Rabbit polyclonal BCL3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human BCL3.

Isotype: IgG

Information d'application

Indications d'application: BCL3 antibody can be used for detection of BCL3 by Western blot at 1 - 2 μg/mL.

Commentaires:

(CT) B-cell CLL/lymphoma 3

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C/-20 °C

Stockage commentaire: BCL3 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Date de péremption: 12 months

Détails sur BCL3

Antigène: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Autre désignation: BCL3 (BCL3 Produits)

Synonymes: anticorps BCL3, anticorps AI528691, anticorps Bcl-3, anticorps BCL4, anticorps D19S37, anticorps B-cell CLL/lymphoma 3, anticorps B cell leukemia/lymphoma 3, anticorps BCL3, anticorps Bcl3

Sujet: The proto-oncogene Bcl-3, believed to be involved in certain human B cell leukemias, encodes a protein that contributes to the regulation of transcriptional activation of NF-k-B target genes. BCL3 contains seven ankyrin repeats, which are most closely related to those found in I-k-B proteins. The expression of this gene can be induced by NF-k-B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-k-B. It contributes to the regulation of cell proliferation. A chromosomal aberration involving BCL3 may be a cause of B-cell chronic lymphocytic leukemia.
Synonyms: B-cell CLL/lymphoma 3, BCL-3, BCL4, D19S37, Proto-oncogene BCL3

Poids moléculaire: 50 kDa (calculated)

ID gène: 602

NCBI Accession: NP_005169

Pathways: Signalisation NF-kappaB, Maintenance of Protein Location, Protein targeting to Nucleus