CARM1 anticorps (N-Term)

N° du produit ABIN1077435

Détail du produit anti-CARM1 anticorps

Antigène: CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CARM1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogène: Rabbit polyclonal CARM1 antibody was raised against a 19 amino acid peptide near the amino terminus of human CARM1.

Isotype: IgG

Information d'application

Indications d'application: CARM1 antibody can be used for detection of CARM1 by Western blot at 1 - 2 μg/mL.

Commentaires:

(NT) Coactivator-associated arginine methyltransferase 1

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C

Stockage commentaire: CARM1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Date de péremption: 12 months

Détails sur CARM1

Antigène: CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))

Autre désignation: CARM1 (CARM1 Produits)

Synonymes: anticorps NV18905, anticorps prmt4, anticorps PRMT4, anticorps Prmt4, anticorps si:dkey-204f11.63, anticorps zgc:100805, anticorps coactivator associated arginine methyltransferase 1, anticorps coactivator associated arginine methyltransferase 1 L homeolog, anticorps coactivator-associated arginine methyltransferase 1, anticorps histone-arginine methyltransferase CARM1, anticorps CARM1, anticorps carm1.L, anticorps Carm1, anticorps carm1, anticorps LOC100352221

Sujet: Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction, metabolism of nascent pre-RNA, and transcriptional activation. CARM1 functions as a transcriptional co-activator for various nuclear receptors and NF-kB. It has also been shown to methylate histone H3 arginines, inhibiting the binding of corepressors and protecting chromatin from deacetylation, thereby facilitating transcription.
Synonyms: Coactivator-associated arginine methyltransferase 1, PRMT4

Poids moléculaire: 67 kDa (calculated)

ID gène: 10498

NCBI Accession: NP_954592

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of fat Cell Differentiation