FOXA1 anticorps
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- Antigène Voir toutes FOXA1 Anticorps
- FOXA1 (Forkhead Box A1 (FOXA1))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FOXA1 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Specificité
- Multiple isoforms of FOXA1 exists as a result of alternative splicing event.
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- Rabbit polyclonal FOXA1 antibody was raised against a 17 amino acid peptide near the center of human FOXA1.
- Isotype
- IgG
- Top Product
- Discover our top product FOXA1 Anticorps primaire
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- Indications d'application
- FOXA1 antibody can be used for detection of FOXA1 by Western blot at 1 - 2 μg/mL.
- Commentaires
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(IN) Forkhead box protein A1
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Stock
- 4 °C/-20 °C
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- Antigène
- FOXA1 (Forkhead Box A1 (FOXA1))
- Autre désignation
- FOXA1 (FOXA1 Produits)
- Synonymes
- anticorps HNF3A, anticorps TCF3A, anticorps Hnf-3a, anticorps Hnf3a, anticorps Tcf-3a, anticorps Tcf3a, anticorps fkd7, anticorps forkhead-7, anticorps HNF3-alpha, anticorps HNF3alpha, anticorps fkh2, anticorps foxa1, anticorps hnf3a, anticorps tFoxA1, anticorps tcf3a, anticorps xfkh2, anticorps fkh, anticorps FOXA1, anticorps Ci-fkh, anticorps HNF-3a, anticorps forkhead box A1, anticorps forkhead box A1 S homeolog, anticorps forkhead homolog, anticorps forkhead box A1 L homeolog, anticorps FOXA1, anticorps Foxa1, anticorps foxa1, anticorps foxa1.S, anticorps fkh, anticorps foxa1.L
- Sujet
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FOXA1 is one of three members of the FOXA family, a subset of the forkhead family of transcription factors which play vital roles in development. It has also been implicated in the development of a number of other organs including the androgen and estrogen regulated tissues of the breast and prostate. FOXA1 modulates the transcriptional activity of nuclear hormone receptors and regulates apoptosis by inhibiting the expression of BCL-2. It is an essential protein for the transcriptional activity of both androgen receptor (AR) and estrogen receptor-alpha (ER). FOXA1 plays a pivotal role from early stage cancer through to drug resistant and metastatic disease. FOXA1 is not only an attractive therapeutic target but could potentially function as a novel biomarker.
Synonyms: Forkhead box protein A1, hepatocyte nuclear factor 3-alpha, HNF3A, HNF-3A, HNF-3-alpha, Transcription factor 3A, TCF3A, TCF-3A - Poids moléculaire
- 52 kDa
- ID gène
- 3169
- NCBI Accession
- NP_004487
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis
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