SDPR anticorps (N-Term)

N° du produit ABIN1077452

Détail du produit anti-SDPR anticorps

Antigène: SDPR (Serum Deprivation Response (SDPR))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SDPR est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: It is predicted to not cross-react with other members of the cavin family.

Purification: Affinity chromatography purified via peptide column

Immunogène: Rabbit polyclonal SDPR antibody was raised against an 18 amino acid peptide near the amino terminus of human SDPR.

Isotype: IgG

Information d'application

Indications d'application: SDPR antibody can be used for detection of SDPR by Western blot at 1 - 2 μg/mL.

Commentaires:

(NT) Serum deprivation-response protein

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C/-20 °C

Détails sur SDPR

Antigène: SDPR (Serum Deprivation Response (SDPR))

Autre désignation: SDPR (SDPR Produits)

Synonymes: anticorps CAVIN2, anticorps PS-p68, anticorps SDR, anticorps cavin-2, anticorps sdr, anticorps MGC84112, anticorps sdprb, anticorps wu:fb39c08, anticorps wu:fk90b02, anticorps zgc:92231, anticorps caveolae associated protein 2, anticorps caveolae associated 2, anticorps caveolae associated protein 2 S homeolog, anticorps serum deprivation response, anticorps caveolae associated protein 2b, anticorps CAVIN2, anticorps Cavin2, anticorps cavin2.S, anticorps SDPR, anticorps cavin2b

Sujet: The serum deprivation-response protein (SDPR) is a calcium-independent phospholipid-binding protein whose expression is increased in serum-starved cells. SDPR is a substrate for protein kinase C (PKC) phosphorylation and recruits the polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation. Both SDPR and PTRF, as well as the other member of the cavin family PRKCDBP were down regulated in breast cancer cell lines and breast tumor tissue, suggesting that expression of the cavin family proteins could be a useful prognostic indicator of breast cancer progression.
Synonyms: Serum deprivation response, SDR, serum deprivation-response protein, CAVIN2, PS-p68, cavin-2, phosphatidylserine binding protein

Poids moléculaire: 47 kDa

ID gène: 8436

NCBI Accession: NP_004648