TSH receptor anticorps (Extracellular Domain)

N° du produit ABIN1104855

Détail du produit anti-TSH receptor anticorps

Antigène: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Épitope: AA 101-115, Extracellular Domain

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp TSH receptor est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: Human TSH Receptor. This antibody is expected to recognize reported isoform 1 (NP_000360.2) and isoform 2 (NP_001018046.1). The immunizing peptide sequence corresponds to a part of the extracellular domain.

Homologie: Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon (100%) Monkey, Marmoset, Sheep, Bovine (93%) Galago, Mouse, Rat, Elephant, Panda, Bat, Dog, Feline, Horse, Rabbit, Porcine, Opossum, Guinea pig, Turkey, Zebra finch, Chicken (87%).

Purification: Immunoaffinity purified

Immunogène: Synthetic peptide C-SKVTHIEIRNTRNLT from an internal region of human TSH Receptor (NP_000360.2, NP_001018046.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon (100%), Monkey, Marmoset, Sheep, Bovine (93%), Galago, Mouse, Rat, Elephant, Panda, Bat, Dog, Feline, Horse, Rabbit, Porcine, Opossum, Guinea pig, Turkey, Zebra finch, Chicken (87%).

Type of Immunogen: Synthetic peptide

Information d'application

Indications d'application: Approved: Peptide-ELISA (1:16000), WB (0.5 - 2 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:16000. Western blot: Approx 28kD band observed in Human Thyroid Gland lysates (calculated MW of 28.4kD according to NP_001018046.1). Recommended concentration: 0.5-2 μg/mL.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Minimize freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur TSH receptor

Antigène: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Autre désignation: TSH Receptor / TSHR (TSHR Produits)

Synonymes: anticorps CHNG1, anticorps LGR3, anticorps hTSHR-I, anticorps AI481368, anticorps hypothroid, anticorps hyt, anticorps pet, anticorps TSHRA, anticorps TSH-R, anticorps thyroid stimulating hormone receptor, anticorps tshr, anticorps TSHR, anticorps Tshr

Sujet: Name/Gene ID: TSHR
Subfamily: Glycoprotein hormone
Family: GPCR

Synonyms: TSHR, CHNG1, HTSHR-I, LGR3, Thyrotrophin receptor, TSH-R, TSH receptor, Thyrotropin receptor

ID gène: 7253

NCBI Accession: NP_000360, NP_001018046

UniProt: P16473

Pathways: Thyroid Hormone Synthesis