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c-MYC anticorps (AA 408-439)
MYC
Reactivité: Humain, Souris, Rat
WB, IF, IHC (p), IP
Hôte: Souris
Monoclonal
IMD-3
unconjugated
N° du produit ABIN1105578
Détail du produit anti-c-MYC anticorps
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Antigène
Voir toutes c-MYC (MYC) Anticorps
c-MYC (MYC)
(Myc Proto-Oncogene protein (MYC))
Épitope
Tous les épitopes à travers c-MYC Anticorps.
AA 408-439
Reactivité
Toutes les réactivités sur c-MYC Anticorps
Humain, Souris, Rat
Hôte
Toutes les hôtes sur c-MYC Anticorps
Souris
Clonalité
Toutes les clonalités sur c-MYC Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers c-MYC Anticorps
Cet anticorp c-MYC est non-conjugé
Application
Tous les applications à travers c-MYC Anticorps.
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
Specificité
This antibody recognizes Human c-Myc.
Purification
Affinity Chromatography
Immunogène
Synthetic peptide corresponding to residues 408-439 of the Human p62c-Myc protein.
Clone
IMD-3
Isotype
IgG2a
Top Product
Discover our top product MYC Anticorps primaire
Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Reconstitution
Restore with 1.2 % Sodium Acetate or Neutral PBS
Concentration
0.1 mg/mL
Buffer
1.2 % Sodium Acetate, 0.01 mg Sodium Azide, 2 mg BSA
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
-20 °C
Stockage commentaire
Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Détails sur c-MYC
(cache)
Antigène
c-MYC (MYC)
(Myc Proto-Oncogene protein (MYC))
Autre désignation
C-Myc (MYC Produits )
Synonymes
anticorps MRTL, anticorps MYCC, anticorps bHLHe39, anticorps c-Myc, anticorps CMYC, anticorps c-myc, anticorps C-MYC, anticorps LOC100136746, anticorps ARC, anticorps B430311C09Rik, anticorps MYC, anticorps NOP, anticorps Nop30, anticorps RNCMYC, anticorps mMyc, anticorps AU016757, anticorps Myc2, anticorps Niard, anticorps Nird, anticorps cmyc, anticorps zc-myc, anticorps c-myc II, anticorps myc-B, anticorps myc2, anticorps myc1, anticorps CMyc, anticorps zgc:55680, anticorps CG10798, anticorps D-Myc, anticorps DM, anticorps DMYc, anticorps Dm, anticorps Dmel\CG10798, anticorps Dmyc, anticorps EG:BACN5I9.1, anticorps anon-WO03040301.171, anticorps bHLHe57, anticorps c-MYC, anticorps d-myc, anticorps dMYC, anticorps dMyc, anticorps dMyc1, anticorps da, anticorps dm, anticorps dm/dMyc, anticorps dm/myc, anticorps dmyc, anticorps dmyc1, anticorps l(1)G0139, anticorps l(1)G0354, anticorps l(1)G0359, anticorps myc, anticorps MYC proto-oncogene, bHLH transcription factor, anticorps v-myc myelocytomatosis viral oncogene homolog, anticorps nucleolar protein 3 (apoptosis repressor with CARD domain), anticorps myelocytomatosis oncogene, anticorps MYC proto-oncogene, bHLH transcription factor a, anticorps MYC proto-oncogene, bHLH transcription factor L homeolog, anticorps MYC proto-oncogene, bHLH transcription factor S homeolog, anticorps v-myc myelocytomatosis viral oncogene homolog (avian), anticorps MYC proto-oncogene, bHLH transcription factor b, anticorps CG10798 gene product from transcript CG10798-RB, anticorps MYC, anticorps LOC100136746, anticorps Nol3, anticorps Myc, anticorps myca, anticorps myc.L, anticorps myc.S, anticorps mycb
Sujet
C-Myc is an oncogene that functions both in the stimulation of cell proliferation and in apoptosis. c-Myc elicits its oncogenic activity by causing immortalization, and to a lesser extent the transformation of cells,in addition to several other mechanisms. The c-MYC proto-oncogene encodes a transcription factor that is critical for cell growth and proliferation. It is one of the genes frequently altered in cancer cells in which it exhibits constitutive activity. Downregulation of c-Myc is critical for 2-Methoxyestradiol (2ME2)-induced oxidative stress and apoptosis in AML cells. And its up-regulation is important for promoting lymphocyte cell division, and demonstrating that GFP-c-Myc expression is a marker of proliferating lymphocytes in vivo.Synonyms: BHLHE39, Class E basic helix-loop-helix protein 39, Myc proto-oncogene protein, Transcription factor p64
ID gène
4609
NCBI Accession
NP_002458
UniProt
P01106
Pathways
Signalisation p53 , Cycle Cellulaire , Sensory Perception of Sound , Transition Metal Ion Homeostasis , Mitotic G1-G1/S Phases , Positive Regulation of Endopeptidase Activity , Regulation of Carbohydrate Metabolic Process , Positive Regulation of Response to DNA Damage Stimulus , L'effet Warburg
Vus récemment
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