PAK1 anticorps

N° du produit ABIN110588

L’anticorps anti-PAK1 Polyclonal Lapin est utilisé pour la détection de PAK1 dans des échantillons de Humain. Il a été validé pour WB et IP.

Aperçu rapide pour PAK1 anticorps (ABIN110588)

Antigène: PAK1 (P21-Activated Kinase 1 (PAK1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAK1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-PAK1 anticorps

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Stock: 4 °C

Détails sur PAK1

Antigène: PAK1 (P21-Activated Kinase 1 (PAK1))

Autre désignation: PAK1 (p21-GTPase-Activated Protein Kinase-1)

Sujet: Human p21-GTPase-activated protein kinase 1 (PAK1) is a functional homolog of STE20 of Saccharomyces cerevisiae. PAK1 is a downstream effector of the Rho-family small GTPases Rac and Cdc42. A serine/threonine kinase, PAK1 induces the formation of filopodia and lamelli- podia in Swiss 3T3 cells. PAK1 inhibits myosin light chain kinase, and appears to play a role in the regulation of apoptosis by phosphorylating the death agonist Bad. Membrane targeting of PAK1 induces neurite outgrowth. PAK1 may also regulate NF-.B activation.

Pathways: Signalisation MAPK, Signalisation RTK, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis