TLR4 anticorps

N° du produit ABIN110591

L’anticorps Lapin Polyclonal anti-TLR4 a été validé pour WB, FACS et IP. Il convient pour détecter TLR4 dans des échantillons de Humain.

Aperçu rapide pour TLR4 anticorps (ABIN110591)

Antigène: TLR4 (Toll-Like Receptor 4 (TLR4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR4 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Détail du produit anti-TLR4 anticorps

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Stock: 4 °C

Détails sur TLR4

Antigène: TLR4 (Toll-Like Receptor 4 (TLR4))

Autre désignation: TLR4 (Torr-Like Receptor)

Sujet: TLR4 (Toll-like receptor 4) is a mammalian homologue of the Drosophila Toll protein. The human TLR4 is a 799-residue type-1 trans-membrane protein. The extracellular domain has leucine-rich repeats and the intracellular domain is similar to that of the IL-1 receptor. TLR4 is a receptor for lipopolysaccharide (LPS). In mice that are genetically tolerant to endotoxin, mutations have been identified in the intracellular domain of TLR4 that abolish LPS responsiveness. TLR4 uses a mechanism similar to that of the IL-1 receptor for signal transduction that leads to activation of NF-.B.

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins