CD1b anticorps

N° du produit ABIN1106010

Détail du produit anti-CD1b anticorps

Antigène: CD1b (CD1B)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD1b est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: 100-1A5 binds with CD1b which is a 45 kDa membrane glycoprotein expressed together with beta-2 Microglobulin. This antibody reacts with cortical thymocytes, Langerhans cells interdigitating cells and with pyramidal cells in the brain. It can be applied for characterization of leukemia's and lymphomas.
Cellular Localization: Cell membrane and cytoplasm.

Purification: Purified

Clone: 100-1A5

Isotype: IgM

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur CD1b

Antigène: CD1b (CD1B)

Autre désignation: CD1b (CD1B Produits)

Synonymes: anticorps CD1, anticorps CD1A, anticorps R1, anticorps CD1B3, anticorps CD1B, anticorps CD1-b, anticorps CD1b molecule, anticorps T-cell surface glycoprotein CD1b-3, anticorps CD1b1 molecule, anticorps T-cell surface glycoprotein CD1b1, anticorps CD1B, anticorps LOC443423, anticorps CD1B1, anticorps LOC100720602

Sujet: CD1b which is associated with β2 microglobulin (1) is expressed on cortical thymocytes (moderate), Langerhans cells, interdigitating cells and brain pyramidal cells (1). It is up-regulated in peripheral neuropathy and inflammatory diseases (2,3). CD1b is the member of CD1 family. At least five CD1 genes (CD1a, b, c, d, and e) are identified (1). Unlike other members in CD1 family which have multiple splicing patterns, CD1b only revealed a single membrane RNA product (1). CD1 proteins including CD1b have been demonstrated to restrict T-cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation (4)Synonyms: T-cell surface glycoprotein CD1b

Poids moléculaire: 45 kDa

ID gène: 910