GFAP anticorps (C-Term)

N° du produit ABIN1107343

Détail du produit anti-GFAP anticorps

Antigène: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Épitope: C-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GFAP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects GFAP at C-term. No cross reactivity with other proteins.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Rat.

Purification: Immunogen affinity purified

Immunogène: Synthetic peptide corresponding to a sequence at the C-terminal of human GFAP .Remarks: Sequence is identical to the related rat and mouse sequence.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: 0.2 mL of distilled water will yield a concentration of 0.5 mg/mL.

Buffer: 0.2 mg Na2HPO4, 0.9 mg NaCl, 0.05 mg Thimerosal, 0.05 mg Sodium Azide, 5 mg BSA

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur GFAP

Antigène: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Autre désignation: GFAP (GFAP Produits)

Synonymes: anticorps GFAP, anticorps AI836096, anticorps cb345, anticorps etID36982.3, anticorps gfapl, anticorps wu:fb34h11, anticorps wu:fk42c12, anticorps xx:af506734, anticorps zgc:110485, anticorps glial fibrillary acidic protein, anticorps GFAP, anticorps LOC100136168, anticorps gfap, anticorps Gfap

Sujet: GGlial fibrillary acidic protein (GFAP) is an intermediate-filament (IF) protein that is highly specific for cells of astroglial lineage, although its tissue-specific role is speculative. GFAP has been located in rat kidney glomeruli and peritubular fibroblasts, leydig cells of testis, skin keratinocytes, osteocytes of bones, chondrocytes of epiglottis, bronchus, and stellate-shaped cells of the pancreas and liver. Its expression is essential for normal white matter architecture and blood-brain barrier integrity, and its absence leads to late-onset CNS dysmyelination. GFAP has also been shown to play a role in mitosis by adjusting the filament network present in the cell. During mitosis, there is an increase in the amount of phosphorylated GFAP, and a movement of this modified protein to the cleavage furrow.Synonyms: Glial Fibrillary Acidic Protein

ID gène: 2670

NCBI Accession: NP_001124491

UniProt: P14136