GNRHR anticorps (Extracellular Domain, N-Term)

N° du produit ABIN1107412

Détail du produit anti-GNRHR anticorps

Antigène: GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))

Épitope: AA 1-29, Extracellular Domain, N-Term

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GNRHR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Séquence: MANSASPEQN QHCSAINNSI PLMQGNLPY

Specificité: This Monoclonal antibody A9E4 reacts with GnRH receptors in the anterior pituitary. A9E4 showed specificity for the synthetic peptide in ELISA and Dot blot, it has a higher affinity for the antigen than the GnRH receptor antibody clone F1G4 (Cat.-No. AM32064PU-N). A9E4 specifically stains human GnRH receptors on frozen tissue of the anterior pituitary. Recognition was supported by Western blotting.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Purified

Immunogène: Synthetic peptide corresponding to the amino acids 1-29 of the Human GnRH receptor extracellular domain conjugated to BSA. Splenocytes were fused with SP2/0 mouse myeloma cells. Stability was established by subcloning four times.

Clone: A9E4

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C

Détails sur GNRHR

Antigène: GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))

Autre désignation: GnRH Receptor / GNRHR (GNRHR Produits)

Synonymes: anticorps GNRHR1, anticorps GRHR, anticorps HH7, anticorps LHRHR, anticorps LRHR, anticorps GNRHR, anticorps GH1, anticorps Lhrhr, anticorps GNRHR1/III, anticorps GNRHR2, anticorps xgnrhr, anticorps gnrhr3/ii, anticorps gnrh-r, anticorps gonadotropin releasing hormone receptor, anticorps gonadotropin-releasing hormone receptor, anticorps GNRHR, anticorps Gnrhr, anticorps gnrhr, anticorps gnrh-r

Sujet: Gonadotropin releasing hormone (GnRH) receptor is a protein of 54-60 kDa. GnRH receptor contains seven hydrophobic transmembrane domains connected by hydrophilic extracellular and intracellular loops characteristic of G-protein coupled receptors. GnRH stimulates the gonadotrophs of the anterior pituitary to secrete luteinizing hormone (LH) as well as follicle-stimulated hormone (FSH). The receptor contains of seven hydrophobic transmembrane domains connected by hydrophillic extracellular, and intracellular loops characteristic of G-protein coupled receptors.Synonyms: GRHR, GnRH-R, Gonadotropin-releasing hormone receptor

ID gène: 2798

NCBI Accession: NP_000397

UniProt: P30968