KATNA1 anticorps (C-Term)

N° du produit ABIN1107914

Détail du produit anti-KATNA1 anticorps

Antigène: KATNA1 (Katanin P60 (ATPase Containing) Subunit A 1 (KATNA1))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KATNA1 est non-conjugé

Application: Western Blotting (WB)

Séquence: DDPSKMVMVL AATNFPWDID EALRRRLEKR IYIPLPSAKG REELLRISLR

Réactivité croisée (Details): Species reactivity (tested):Mouse, human.

Purification: Immunoaffinity column

Immunogène: Synthetic peptide directed towards the C-terminal region of mouse Katna1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store lyophilized at 2-8 °C for one month or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Détails sur KATNA1

Antigène: KATNA1 (Katanin P60 (ATPase Containing) Subunit A 1 (KATNA1))

Autre désignation: KATNA1 (KATNA1 Produits)

Synonymes: anticorps si:dkey-15j16.1, anticorps zgc:110580, anticorps katna1, anticorps katanin catalytic subunit A1, anticorps katanin p60 (ATPase containing) subunit A 1, anticorps katanin p60 (ATPase-containing) subunit A1, anticorps KATNA1, anticorps katna1, anticorps Katna1

Sujet: Katna1 severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays, such as that seen during disassembly of interphase microtubules at the G2-M transition.It may also be required for microtubule release from the centrosome after nucleation. In mitotic spindles this could allow depolymerization of the microtubule end proximal to the centrosome, and subsequent poleward microtubule flux. In neurons, microtubule release within the cell body allows their subsequent transport into neuronal processes by microtubule dependent motor proteins. This transport is required for axonal growth.Synonyms: Katanin p60 ATPase-containing subunit A1, Katanin p60 subunit A1, p60 katanin

Poids moléculaire: Katna1: 54 kDa

ID gène: 23924

NCBI Accession: NM_011835

Pathways: Dynamique des Microtubules