MTF1 anticorps (C-Term)

N° du produit ABIN1108308

Détail du produit anti-MTF1 anticorps

Antigène: MTF1 (Metal-Regulatory Transcription Factor 1 (MTF1))

Épitope: C-Term

Reactivité: Humain, Souris, Chien, Rat, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MTF1 est non-conjugé

Application: Western Blotting (WB)

Séquence: QSSLVMGEQN LQWILNGATS SPQNQEQIQQ ASKVEKVFFT TAVPVASSPG

Réactivité croisée (Details): Species reactivity (expected):Mouse (100 %), Rat (100 %), Dog (100 %), Bovine (100 %), Horse (100 %), Guinea Pig (92 %), Rabbit (92 %).
Species reactivity (tested):Human.

Purification: Purified on Protein A affinity column.

Immunogène: The immunogen for anti-MTF1 antibody: synthetic peptide directed towards the C terminal of human MTF1.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Add 100 μL of distilled water to a final concentration of 1 mg/mL

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the lyophised antibody at -20 °C for up to one year. Store reconstitued antibody undiluted for one month or in aliquots at -20 °C long term.

Date de péremption: 12 months

Détails sur MTF1

Antigène: MTF1 (Metal-Regulatory Transcription Factor 1 (MTF1))

Autre désignation: MTF1 (MTF1 Produits)

Synonymes: anticorps MTF-1, anticorps MTF1, anticorps mtf1, anticorps MGC86485, anticorps Thyls, anticorps ZRF, anticorps metal regulatory transcription factor 1, anticorps metal-regulatory transcription factor 1, anticorps metal-regulatory transcription factor 1 L homeolog, anticorps metal response element binding transcription factor 1, anticorps MTF1, anticorps mtf1, anticorps mtf1.L, anticorps Mtf1

Sujet: The zinc finger transcription factor MTF-1 (metal-responsive transcription factor-1) is conserved from insects to vertebrates. The major role of MTF-1 in both organisms is to control the transcription of genes involved in the homeostasis and detoxification of heavy metal ions such as Cu2+, Zn2+ and Cd2+. In mammals, MTF-1 serves at least two additional roles. First, targeted disruption of the MTF-1 gene results in death at embryonic day 14 due to liver degeneration, revealing a stage-specific developmental role. Second, under hypoxic-anoxic stress, MTF-1 helps to activate the transcription of the gene placental growth factor (PIGF), an angiogenic protein.Synonyms: MRE-binding transcription factor, Metal regulatory transcription factor 1, Transcription factor MTF-1

Poids moléculaire: 81 kDa (753 amino acids)

ID gène: 4520

NCBI Accession: NP_005946