Muscarinic Acetylcholine Receptor M2 anticorps (C-Term)

N° du produit ABIN1108326

Détail du produit anti-Muscarinic Acetylcholine Receptor M2 anticorps

Antigène: Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))

Épitope: AA 451-466, C-Term

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Muscarinic Acetylcholine Receptor M2 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibopdy detects Muscarinic acetylcholine receptor M2 (C-term). It shows no cross reactivity with other proteins.

Réactivité croisée (Details): Species reactivity (tested):Rat

Purification: Immunogen affinity chromatography

Immunogène: Synthetic peptide corresponding to a sequence at the C-terminal of human CHRM2 (451-466aa), identical to the related rat sequence

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur Muscarinic Acetylcholine Receptor M2

Antigène: Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))

Autre désignation: Muscarinic Acetylcholine Receptor M2 (CHRM2 Produits)

Synonymes: anticorps HM2, anticorps AChR-M2, anticorps Chrm-2, anticorps M2, anticorps chrm2, anticorps Acm2, anticorps GPM2, anticorps cholinergic receptor muscarinic 2, anticorps cholinergic receptor, muscarinic 2, cardiac, anticorps cholinergic receptor, muscarinic 2a, anticorps cholinergic receptor, muscarinic 2, anticorps CHRM2, anticorps Chrm2, anticorps chrm2a

Sujet: The muscarinic acetylcholine receptor M2, also known as the cholinergic receptor, muscarinic 2, is a muscarinic acetylcholine receptor. The M2 muscarinic receptors are located in the heart, where they act to slow the heart rate down to normal sinus rhythm after stimulatory actions of the sympathetic nervous system, by slowing the speed of depolarization. The CHRM2 gene inhibits the release of acetylcholine from cholinergic fibers in the lungs and elsewhere. In airway parasympathetic neurons, it is decreased by viral infections and by interferon-gamma, increasing actylcholine release. This gene is thought to be involved in neuronal excitability, synaptic plasticity and feedback regulation of acetylcholine release and has previously been implicated in higher cognitive processing. In a sample of 667 individuals from 304 families, Gosso MF et al. genotyped three single-nucleotide polymorphisms (SNPs) in the CHRM2 gene on 7q31-35. CHRM2 is implicated in memory and cognition, functions impaired in many neuropsychiatric disorders.Synonyms: CHRM2, mAChR M2, mAChR-M2

ID gène: 81645

NCBI Accession: NP_112278

UniProt: P10980