NEFL anticorps

N° du produit ABIN1108415

Détail du produit anti-NEFL anticorps

Antigène: NEFL (Neurofilament, Light Polypeptide (NEFL))

Reactivité: Humain, Rat, Porc

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NEFL est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: This antibody reacts to Neurofilament L (68 kDa).

Purification: Affinity chromatography

Clone: NF-68

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 1.2 % sodium acetate or neutral PBS

Concentration: 0,1 mg/mL

Buffer: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur NEFL

Antigène: NEFL (Neurofilament, Light Polypeptide (NEFL))

Autre désignation: Neurofilament L (68kDa) (NEFL Produits)

Synonymes: anticorps NEFL, anticorps nefl, anticorps zgc:136626, anticorps AI847934, anticorps CMT2E, anticorps NF-L, anticorps NF68, anticorps Nfl, anticorps CMT1F, anticorps NFL, anticorps XNF-L, anticorps neurofilament light, anticorps neurofilament, light polypeptide, anticorps neurofilament, light polypeptide b, anticorps neurofilament, light L homeolog, anticorps NEFL, anticorps neflb, anticorps Nefl, anticorps nefl.L

Sujet: Neurofilaments are composed of 3 neuron-specific proteins with apparent molecular masses of 68 Kd (NFL), 125 kD (NFM) and 200 kD (NFH) on SDS-gel electrophoresis. And they have a role in the maturation of regenerating myelinated axons. Neurofilament 68 (NF68), also called Neurofilament rotein, Light Chain (NFL). It is one of the most abundant cytoskeletal omponents of the neuron.Mutations in this gene were reported as a cause for autosomal dominant Charcot-Marie-Tooth type 2E (CMT2E) linked to chromosome 8p21. NFL was identified repeatedly in both screenings and found to interact with Myotubularin-related 2 gene, MTMR2 in both Schwann cells and neurons.Synonyms: 68 kDa neurofilament protein, NEFL, NF-L, NF68, Neurofilament L

ID gène: 4747

NCBI Accession: NP_006149

UniProt: P07196